Bidirectional transcriptional activity of PGK-neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice

Genesis

Volumn 30, Issue 4, 2001, Pages 259-263

  Scacheri, P C ^a,b   Crabtree, J S ^a,b   Novotny, E A ^a,b   Garrett Beal, L ^a,b   Chen, A ^a,b   Edgemon, K A ^a,b   Marx, S J ^a,b   Spiegel, A M ^a,b   Chandrasekharappa, S C ^a,b   Collins, F S ^a,b  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; MEN1 PROTEIN; PGK NEOMYCIN PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EMBRYO DEATH; GENE DISRUPTION; GENE TARGETING; HETEROZYGOTE; IMMUNOPRECIPITATION; KNOCKOUT MOUSE; MOUSE; MULTIPLE ENDOCRINE NEOPLASIA; NONHUMAN; NORTHERN BLOTTING; OMPHALOCELE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CHIMERA; EMBRYO; EMBRYO LOSS; EXONS; GENE DELETION; GENE TARGETING; GENES, DOMINANT; GENES, LETHAL; GENES, REPORTER; HERNIA, UMBILICAL; HETEROZYGOTE; MICE; MICE, KNOCKOUT; MUTAGENESIS, INSERTIONAL; NEOMYCIN; NEOPLASM PROTEINS; PHENOTYPE; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0034876289     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.1072     Document Type: Article

References (9)

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