Activation by prion peptide PrP106-126 induces a NF-κB-driven proinflammatory response in human monocyte-derived dendritic cells

Journal of Leukocyte Biology

Volumn 74, Issue 1, 2003, Pages 118-125

  Bacot, Silvia M ^a   Lenz, Petra ^b   Frazier Jessen, Michelle R ^a   Feldman, Gerald M ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Cell signaling; Inflammation; TSE

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PRION PROTEIN; PRP 106 126 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; FORMYLMETHIONYLLEUCYLPHENYLALANINE; PEPTIDE FRAGMENT; PRION PROTEIN (106 126); PRION PROTEIN (106-126);

ARTICLE; AUTOCRINE EFFECT; CELL ACTIVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; HUMAN; HUMAN CELL; MONOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION; BIOSYNTHESIS; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION REGULATION; IMMUNOLOGY; INFLAMMATION; METABOLISM; PHYSIOLOGY; PRION; PRION DISEASE;

CYTOKINES; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; MONOCYTES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NF-KAPPA B; PEPTIDE FRAGMENTS; PRION DISEASES; PRIONS;

EID: 0042570765     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1102521     Document Type: Article

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