The Stimulation of Inducible Nitric-oxide Synthase by the Prion Protein Fragment 106-126 in Human Microglia is Tumor Necrosis Factor-α-dependent and Involves p38 Mitogen-activated Protein Kinase

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 25692-25696

  Fabrizi, Cinzia ^a   Silei, Valerio ^a   Menegazzi, Marta ^b   Salmona, Mario ^c   Bugiani, Orso ^d   Tagliavini, Fabrizio ^d   Suzuki, Hisanori ^b   Lauro, Giuliana Maria ^a  

^a ROMA TRE UNIVERSITY   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; ENZYME INHIBITION; GENES; TUMORS;

MICROGLIAL ACTIVATION;

BIOCHEMISTRY;

AMINO ACID; BLOCKING ANTIBODY; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE SYNTHASE; PRION PROTEIN; PRION PROTEIN[102-126]; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG; MITOGEN ACTIVATED PROTEIN KINASE; NOS2A PROTEIN, HUMAN; PEPTIDE FRAGMENT; PRION PROTEIN (106 126); PRION PROTEIN (106-126);

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; MICROGLIA; NEUROTOXICITY; NOS II GENE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PRION; SIGNAL TRANSDUCTION;

CELLS, CULTURED; GENE EXPRESSION REGULATION; HUMANS; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE FRAGMENTS; PRIONS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035854802     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100133200     Document Type: Article

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