Differentiation-dependent p53 regulation of nucleotide excision repair in keratinocytes

American Journal of Pathology

Volumn 150, Issue 4, 1997, Pages 1457-1464

  Li, Gang ^a   Ho, Vincent C ^a   Mitchell, David L ^b   Trotter, Martin J ^a   Tron, Victor A ^a,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF TEXAS   (United States)

^c VANCOUVER GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA DAMAGE; EXCISION REPAIR; GROWTH REGULATION; HUMAN; HUMAN CELL; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN CANCER; SKIN CARCINOGENESIS; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; DNA REPAIR; HUMANS; KERATINOCYTES; MICE; MICE, TRANSGENIC; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 0031002037     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Hollstein M, Sidransky D, Vogelstein B, Harris CC: p53 mutations in human cancers. Science 1991, 253:49-53
2. Levine AJ, Monand J, Finlay CA: The p53 tumour suppressor gene. Nature 1991, 351:453-456
3. Brash DE, Rudolph JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, Ponten JA: A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 1991, 88: 10124-10128
4. Burns JE, Baird MC, Clark LJ, Burns PA, Edington K, Chapman C, Mitchell R, Robertson G, Soutar D, Parkinson EK: Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines. Br J Cancer 1993, 67:1274-1284
5. Kress S, Christian S, Strickland PT, Mukhtar H, Schweizer J, Schwarz M: Carcinogen-specific mutational pattern in the p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin. Cancer Res 1992, 52:6400-6403
6. Kanjilal S, Pierceall WE, Cummings KK, Kripke ML, Anathaswamy HN: High frequency of p53 mutations in ultraviolet radiation-induced murine skin tumors: evidence for strand bias and tumor heterogeneity. Cancer Res 1993, 53:2961-2964
7. Rady P, Scinicaiello F, Wagner RF Jr, Tyring SK: p53 mutations in basal cell carcinomas. Cancer Res 1992, 52:3804-3806
8. Dumaz N, Drougard C, Sarasin A, Daya-Grosjean L: Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients. Proc Natl Acad Sci USA 1993, 90:10529-10533
9. Taguchi M, Watanabe S, Sato Y, Kameya T, Munakata N, Ishihara K, Nakane PK, Hisatome H, Ikeda S: Immunohistochemical examination of tumor-suppressor gene p53 product and pyrimidine dimer in solar keratosis. J Cancer Res Clin Oncol 1993, 119:260-262
10. McGregor JM, Yu CC, Dublin EA, Levison Da, MacDonald DM: Aberrant expression of p53 tumour-suppressor protein in non-melanoma skin cancer. Br J Dermatol 1992, 127:463-469
11. Sim CS, Slater S, McKee PH: Mutant p53 expression in solar keratosis: an immunohistochemical study. J Cutan Pathol 1992, 19:302-308
12. Ziegler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, Kimmelman J, Remington L, Jacks T, Brash DE: Sunburn and p53 in the onset of skin cancer. Nature 1994, 372:773-776
13. Laviguer A, Maltby V, Mock D, Rossant J, Pawson T, Bernstein A: High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene. Mol Cell Biol 1989, 9:3982-3991
14. Li G, Ho VC, Berean K, Tron VA: Ultraviolet radiation induction of squamous cell carcinomas in p53 transgenic mice. Cancer Res 1995, 55:2070-2074
15. Kastan MB, Canman CE, Leonard CJ: p53, cell cycle control and apoptosis: implications for cancer. Cancer Metastasis Rev 1995, 14:3-15
16. Hainaut P: The tumor suppressor protein p53: a receptor to genotoxic stress that controls cell growth and survival. Curr Opin Oncol 1995, 7:76-82
17. Hall PA, McKee PH, Menage HD, Dover R, Lane DP: High levels of p53 protein in UV-irradiated normal human skin. Oncogene 1993, 8:203-207
18. Yamaizumi M, Sugano T: U.V.-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycle. Oncogene 1994, 9:2775-2784
19. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW: Participation of p53 protein in the cellular response to DNA damage. Cancer Res 1991, 51: 6304-6311
20. Kastan MB, Zhan Q, el-Deiry WS, Carrier F, Jacks T, Walsh WV, Plunkett BS, Vogelstein B, Fornace AJ Jr: A mammalian cell cycle checkpoint pathway, Cell 1992, 71:587-597
21. Li G, Mitchell DL, Ho VC, Reed JC, Tron VA: Decreased DNA repair but normal apoptosis in ultraviolet-irradiated skin of p53-transgenic mice. Am J Pathol 1996, 148:1113-1123
22. Smith ML, Chen IT, Zhan Q, O'Connor PM, Fornace AJ Jr: Involvement of the p53 tumor suppressor in repair of U.V.-type DNA. Oncogene 1995, 10:1053-1059
23. Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T: p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 1993, 362:847-849
24. Miyashita T, Harigai M, Hanada M, Reed JC: Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res 1994, 54:3131-3135
25. Miyashita T, Krajewski S, Krajewska M, Wang HG, Lin HK, Liebermann DA, Hoffman B, Reed JC: Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 1994, 9:1799-1805
26. El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B: WAF1, a potential mediator of p53 tumor suppression. Cell 1993, 75:817-825
27. Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ: The p21 Cdk-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993, 75:805-816
28. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R, Beach D: p21 is a universal inhibitor of cyclin kinases. Science 1993, 366:701-704
29. Sancar A: Mechanisms of DNA excision repair. Science 1994, 266:1954-1956
30. Wang XW, Forrester K, Yeh H, Feitelson MA, Gu JR, Harris CC: Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc Natl Acad Sci USA 1994, 91:2230-2234
31. Wang XW, Yeh H, Schaeffer L, Roy R, Moncollin V, Egly JM, Wang Z, Freidberg EC, Evans MK, Taffe BG: p53 modulation of TFIIH-associated nucleotide excision repair activity. Nature Genet 1995, 10:188-195
32. Coverley D, Kenny MK, Lane DP, Wood RD: A role for the human single-stranded DNA binding protein HSSB/ RPA in an early stage of nucleotide excision repair. Nucleic Acids Res 1992, 20:3873-3880
33. Dutta A, Ruppert JM, Aster JC, Winchester E: Inhibition of DNA replication factor RPA by p53. Nature 1993, 365:79-82
34. Bakalkin G, Yakovleva T, Selivanova G, Magnusson KP, Szekely L, Kiseleva E, Klein G, Terenius L, Wiman KG: p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer. Proc Natl Acad Sci USA 1994, 91:413-417
35. Ford JM, Hanawalt PC: Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance. Proc Natl Acad Sci USA 1995, 92:8876-8880
36. Mirzayans R, Enns L, Dietrich K, Barley RD, Paterson MC: Faulty DNA polymerase δ/ε-mediated excision repair in response to γ-radiation or ultraviolet light in p53-deficient fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome. Carcinogenesis 1996, 17:691-698
37. Yin Y, Tainsky MA, Bischoff FZ, Strong LC, Geoffrey MW: Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 1992, 70:937-948
38. Livingstone LR, White A, Sprouse J, Livanos E, Jacks T, Tlsty TD: Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 1992, 70:923-935
39. Donahower LA, Harvey M, Slagle BL, McArther MJ, Montgomery CA Jr, Butel JS, Bradley A: Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 1992, 356:215-221
40. Mitchell DL: Radioimmunoassay of DNA damaged by ultraviolet light, Technologies for Detection of DNA Damage and Mutations. Edited by G Pfeifer. New York, Plenum, pp 73-85
41. Mood AM, Graybill FA, Boes DC: Introduction of the Theory of Statistics, ed 3. Edited by AM Mood, FA Graybill, DC Boes. Toronto, McGraw-Hill, 1974, pp 175-218
42. Athas WF, Hedayati MA, Matanosk GM, Farmer ER, Grossman L: Development and field-test validation of an assay for DNA repair in circulating human lymphocytes. Cancer Res 1991, 51:5786-5793
43. Weinberg WC, Azzoli CG, Chapman K, Levine AJ, Yuspa SH: p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein. Oncogene 1995, 10:2271-2279
44. Boyce ST, Ham RG: Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture. J Invest Dermatol 1983, 33s-40s
45. Harvey M, Vogel H, Morris D, Bradley A, Bernstein A, Donehower LA: A mutant p53 transgenic accelerates tumor development in heterozygous but not nullizygous p53-deficient mice. Nature Genet 1995, 9:305-311
46. Donner EM, Preston RJ: The relationship between p53 status, DNA repair and chromatid aberration induction in G2 mouse embryo fibroblast cells treated with bleomycin. Carcinogenesis 1996, 17:1161-1165
47. Ishizaki K, Ejima Y, Matsunaga T, Hara R, Sakamoto A, Ikenaga M, Ikawa Y, Aizawa S: Increased UV-induced SCEs but normal repair of DNA damage in p53-deficient mouse cells. Int J Cancer 1994, 58:254-257
48. Scherer SJ, Welter C, Zang KD, Dooley S: Specific in vitro binding of p53 to the promoter region of the human mismatch repair gene hMSH2. Biochem Biophys Res Commun 1996, 221:722-728
49. Boulikas T: DNA lesion-recognizing proteins and the p53 connection. Anticancer Res 1996, 16:225-242
50. Leveillard T, Andera L, Bissonnette N, Schaeffer L, Bracco L, Egly JM, Wasylyk B: Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations. EMBO J 1996, 15:1615-1624
51. McWhir J, Selfridge J, Harrison DJ, Squires S, Melton DW: Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning. Nature Genet 1993, 5:217-224
52. Lee JM, Bernstein A: p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci USA 1993, 90:5742-5746
53. Gilchrest BA, Soter NA, Stoff JS, Mihm MC Jr: The human sunburn reaction: histologic and biochemical studies. J Am Acad Dermatol 1981, 5:411-422