Ca2+-independent protein kinase C activity is required for α1-adrenergic-receptor-mediated regulation of ribosomal protein S6 kinases in adult cardiomyocytes

Biochemical Journal

Volumn 373, Issue 2, 2003, Pages 603-611

  Wang, Lijun ^a   Rolfe, Mark ^a   Proud, Christopher G ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Cardiac hypertrophy; p70 S6 kinase; Phenylephrine; Protein kinase C; Protein synthesis; Translation initiation

Indexed keywords

BIOLOGICAL MEMBRANES; CALCIUM; SYNTHESIS (CHEMICAL);

PHENYLEPHRINE (PE);

PROTEINS;

ADENOVIRUS VECTOR; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; BISINDOLYLMALEIMIDE; CALCIUM ION; ELONGATION FACTOR 2; INITIATION FACTOR 4E; MITOGEN ACTIVATED PROTEIN KINASE; PHENYLEPHRINE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RAPAMYCIN; S6 KINASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE TRANSFER; HEART HYPERTROPHY; HEART MUSCLE CELL; IMMUNOBLOTTING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; RNA TRANSLATION; SIGNAL TRANSDUCTION; TRANSLATION INITIATION;

ACETOPHENONES; ADENOVIRIDAE; ADRENERGIC ALPHA-AGONISTS; ANIMALS; BENZOPYRANS; CALCIUM; ENZYME ACTIVATION; ENZYME INHIBITORS; GENES, DOMINANT; INDOLES; MALEIMIDES; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCYTES, CARDIAC; PHENYLEPHRINE; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN KINASE C; PROTEIN TRANSPORT; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SIGNAL TRANSDUCTION; SIROLIMUS;

ADENOVIRIDAE; ANIMALIA; EUKARYOTA; MAMMALIA;

EID: 0042346242     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030454     Document Type: Article

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