Role of protein kinase C-ε in hypertrophy of cultured neonatal rat ventricular myocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 2 49-2, 2001, Pages

  Strait III, James B ^a   Martin, Jody L ^a   Bayer, Allison ^a   Mestril, Ruben ^a   Eble, Diane M ^a   Samarel, Allen M ^a,b  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Adenovirus; Endothelin 1; Extracellular signal regulated kinase; Heart; Signal transduction

Indexed keywords

ATRIAL NATRIURETIC FACTOR; ENDOTHELIN; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; MYOSIN HEAVY CHAIN; PROTEIN KINASE C;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL GROWTH; CELL SHAPE; CELL SURFACE; CONTROLLED STUDY; ENZYME SUBUNIT; GENE OVEREXPRESSION; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART VENTRICLE; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

EID: 0035010371     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.2.h756     Document Type: Article

References (47)

1. Aoki H, Richmond M, Izumo S, and Sadoshima J. Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro. Biochem J 347: 275-284, 2000.
2. Barr E, Carroll J, Kalynych AM, Tripathy SK, Kozarsky K, Wilson JM, and Leiden JM. Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus. Gene Ther 1: 51-58, 1994.
3. Benjamin EJ and Levy D. Why is left ventricular hypertrophy so predictive of morbidity and mortality? Am J Med Sci 317: 168-175, 1999.
4. Bogoyevitch MA, Glennon PE, Andersson MB, Clerk A, Lazou A, Marshall CJ, Parker PJ, and Sugden PH. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy. J Biol Chem 269: 1110-1119, 1994.
5. Bogoyevitch MA, Ketterman AJ, and Sugden PH. Cellular stresses differentially activate c-Jun N-terminal protein kinases and extracellular signal-regulated protein kinases in cultured ventricular myocytes. J Biol Chem 270: 29710-29717, 1995.
6. Bogoyevitch MA, Parker PJ, and Sugden PH. Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-ε is a major isotype present, and it is activated by phorbol esters, epinephrine, and endothelin. Circ Res 72: 757-767, 1993.
7. Borg TK, Goldsmith EC, Price R, Carver W, Terracio L, and Samarel AM. Specialization at the Z line of cardiac myocytes. Cardiovasc Res 46: 277-285, 2000.
8. Cadre BM, Qi M, Eble DM, Shannon TR, Bers DM, and Samarel AM. Cyclic stretch down-regulates calcium transporter gene expression in neonatal rat ventricular myocytes. J Mol Cell Cardiol 30: 2247-2259, 1998.
9. Chassagne C, Wisnewsky C, and Schwartz K. Antithetical accumulation of myosin heavy chain but not α-actin mRNA isoforms during early stages of pressure-overload-induced rat cardiac hypertrophy. Circ Res 72: 857-864, 1993.
10. Chiloeches A, Paterson HF, Marais R, Clerk A, Marshall CJ, and Sugden PH. Regulation of Ras, GTP loading and Ras-Raf association in neonatal rat ventricular myocytes by G protein-coupled receptor agonists and phorbol ester activation of the extracellular signal-regulated kinase cascade by phorbol ester is mediated by Ras. J Biol Chem 274: 19762-19770, 1999.
11. Chomczynski P and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
12. Choukroun G, Hajjar R, Kyriakis JM, Bonventre JV, Rosenzweig A, and. Force T. Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy. J Clin Invest 102: 1311-1320, 1998.
13. Clerk A, Bogoyevitch MA, Anderson MB, and Sugden PH. Differential activation of protein kinase C isoforms by endothelin-1 and phenylephrine and subsequent stimulation of p42 and p44 mitogen-activated protein kinases in ventricular myocytes cultured from neonatal rat hearts. J Biol Chem 269: 32848-32857, 1994.
14. Dabiri GA, Turnacioglu KK, Sanger JM, and Sanger JW. Myofibrillogenesis visualized in living embryonic cardiomyocytes. Proc Natl Acad Sci USA 94: 9493-9498, 1997.
15. Decock JB, Gillespie-Brown J, Parker PJ, Sugden PH, and Fuller SJ. Classical, novel and atypical isoforms of PKC stimulate ANF- and TRE/AP-1-regulated-promoter activity in ventricular cardiomyocytes. FEBS Lett 356: 275-278, 1994.
16. Disatnik MH, Buraggi G, and Mochly-Rosen D. Localization of protein kinase C isozymes in cardiac myocytes. Exp Cell Res 210: 287-297, 1994.
17. Doble BW, Ping P, and Kardami E. The ε subtype of protein kinase C is required for cardiomyocyte connexin-43 phosphorylation. Circ Res 86: 293-301, 2000.
18. Eble DM, Qi M, Waldschmidt S, Lucchesi PA, Byron KL, and Samarel AM. Contractile activity is required for sarcomeric assembly in phenylephrine-induced cardiac myocyte hypertrophy. Am J Physiol Cell Physiol 274: C1226-C1237, 1998.
19. Eble DM, Strait JB, Govindarajan G, Lou J, Byron KL, and Samarel AM. Endothelin-induced cardiac myocyte hypertrophy: role for focal adhesion kinase. Am J Physiol Heart Circ Physiol 278: H1695-H1707, 2000.
20. Fuller SJ, Gillespie-Brown J, and Sugden PH. Oncogenic src, raf, and ras stimulate a hypertrophic pattern of gene expression and increase cell size in neonatal rat ventricular myocytes. J Biol Chem 273: 18146-18152, 1998.
21. Ho PD, Zechner DK, He H, Dillmann WH, Glembotski CC, and McDonough PM. The Raf-MEK-ERK cascade represents a common pathway for alteration of intracellular calcium by Ras and protein kinase C in cardiac myocytes. J Biol Chem 273: 21730-21735, 1998.
22. Hodge CW, Mehmert KK, Kelley SP, McMahon T, Haywood A, Olive MF, Wang D, Sanchez-Perez AM, and Messing RO. Supersensitivity to allosteric GABA(A) receptor modulators and alcohol in mice lacking PKCepsilon. Nature 2: 997-1002, 1999.
23. Ito H, Hirata Y, Hiroe M, Tsujino M, Adachi S, Takamoto T, Nitta M, Taniguchi K, and Marumo F. Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes. Circ Res 69: 209-215, 1991.
24. Jiang T, Pak E, Zhang HL, Kline RP, and Steinberg SF. Endothelin-dependent actions in cultured AT-1 cardiac myocytes. The role of the ε isoform of protein kinase C. Circ Res 78: 724-736, 1996.
25. Kariya K, Karns LR, and Simpson PC. Expression of a constitutively activated mutant of the β-isozyme of protein kinase C in cardiac myocytes stimulates the promoter of the beta-myosin heavy chain isogene. J Biol Chem 266: 10023-10026, 1991.
26. Khasar SG, Lin YH, Martin A, Dadgar J, McMahon T, Wang D, Hundle B, Aley KO, Isenberg W, McCarter G, Green PG, Hodge CW, Levine JD, and Messing RO. A novel nociceptor signaling pathway revealed in protein kinase C ε mutant mice. Neuron 24: 253-260, 1999.
27. Kim L, Lee T, Fu J, and Ritchie ME. Characterization of MAP kinase and PKC isoform and effect of ACE inhibition in hypertrophy in vivo. Am J Physiol Heart Circ Physiol 277: H1808-H1816, 1999.
28. Mochly-Rosen D, Wu G, Hahn H, Osinska H, Liron T, Lorenz JN, Yatani A, Robbins J, and Dorn GW II. Cardiotrophic effects of protein kinase C ε: analysis by in vivo modulation of PKCε translocation. Circ Res 86: 1173-1179, 2000.
29. Montessuit C and Thorburn A. Activation of Ras by phorbol esters in cardiac myocytes. Role of guanine nucleotide exchange factors. FEBS Lett 460: 57-60, 1999.
30. Ping P, Zhang J, Cao X, Li RC, Kong D, Tang XL, Qiu Y, Manchikalapudi S, Auchampach JA, Black RG, and Bolli R. PKC-dependent activation of p44/p42 MAPKs during myocardial ischemia-reperfusion in conscious rabbits. Am J Physiol Heart Circ Physiol 276: H1468-H1481, 1999.
31. Puceat M, Hilal-Dandan R, Strulovici B, Brunton LL, and Brown JH. Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes. J Biol Chem 269: 16938-16944, 1994.
32. 2+-ATPase gene expression in cultured neonatal rat heart cells. Am J Physiol Heart Circ Physiol 271: H1031-H1039, 1996.
33. Qi M, Ojamaa K, Eleftheriades EG, Klein I, and Samarel AM. Regulation of rat ventricular myosin heavy chain expression by serum and contractile activity. Am J Physiol Cell Physiol 267: C520-C528, 1994.
34. i and contractile activity. Am J Physiol Cell Physiol 273: C394-C403, 1997.
35. Rybin VO and Steinberg SF. Protein kinase C isoform expression and regulation in the developing rat heart. Circ Res 74: 299-309, 1994.
36. Samarel AM and Engelmann GL. Contractile activity modulates myosin heavy chain-β expression in neonatal rat heart cells. Am J Physiol Heart Circ Physiol 261: H1067-H1077, 1991.
37. Samarel AM, Spragia ML, Maloney V, Kamal SA, and Engelmann GL. Contractile arrest accelerates myosin heavy chain degradation in neonatal rat heart cells. Am J Physiol Cell Physiol 263: C642-C652, 1992.
38. Sharp WW, Simpson DG, Borg TK, Samarel AM, and Terracio L. Mechanical forces regulate focal adhesion and costamere assembly in cardiac myocytes. Am J Physiol Heart Circ Physiol 273: H546-H556, 1997.
39. Shubeita HE, Martinson EA, Van Bilsen M, Chien KR, and Brown JH. Transcriptional activation of the cardiac myosin light chain 2 and atrial natriuretic factor genes by protein kinase C in neonatal rat ventricular myocytes. Proc Natl Acad Sci USA 89: 1305-1309, 1992.
40. Shubeita HE, McDonough PM, Harris AN, Knowlton KU, Glembotski CC, Brown JH, and Chien KR. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy. J Biol Chem 265: 20555-20562, 1990.
41. Strait JB and Samarel AM. Isoenzyme-specific protein kinase C and c-Jun N-terminal kinase activation by electrically stimulated contraction of neonatal rat ventricular myocytes. J Mol Cell Cardiol 32: 1553-1566, 2000.
42. Sugden PH and Clerk A. Cellular mechanisms of cardiac hypertrophy. J Mol Med 76: 725-746, 1998.
43. Takeishi Y, Ping P, Bolli R, Kirkpatrick DL, Hoit BD, and Walsh RA. Transgenic overexpression of constitutively active protein kinase C ε causes concentric cardiac hypertrophy. Circ Res 86: 1218-1223, 2000.
44. Thorburn A, Thorburn J, Chen SY, Powers S, Shubeita HE, Feramisco JR, and Chien KR. HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. J Biol Chem 268: 2244-2249, 1993.
45. Ueyama T, Kawashima S, Sakoda T, Rikitake Y, Ishida T, Kawai M, Yamashita T, Ishido S, Hotta H, and Yokayama M. Requirement of activation of the extracellular signal-regulated kinase cascade in myocardial cell hypertrophy. J Mol Cell Cardiol 32: 947-960, 2000.
46. 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes. J Clin Invest 85: 1206-1214, 1990.
47. Wotton D, Ways DK, Parker PJ, and Owen MJ. Activity of both Raf and Ras is necessary for activation of transcription of the human T cell receptor beta gene by protein kinase C, Ras plays multiple roles. J Biol Chem 268: 17975-17982, 1993.