Ontogenic differences in human liver 4-hydroxynonenal detoxification are associated with in vitro injury to fetal hematopoietic stem cells

Toxicology and Applied Pharmacology

Volumn 191, Issue 2, 2003, Pages 95-106

  Gardner, James L ^a   Doi, Adriana M ^a   Pham, Robert T ^a   Huisden, Christiaan M ^a   Gallagher, Evan P ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

4 Hydroxynon 2 enal metabolism; Hematopoietic stem cells; Human liver; Ontogeny

Indexed keywords

4 HYDROXYNONENAL; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; ALDEHYDE REDUCTASE; GLUTATHIONE TRANSFERASE;

ARTICLE; CELL FRACTIONATION; CELL PROTECTION; CELL SUBPOPULATION; CELL VIABILITY; COMPLEX FORMATION; CONJUGATION; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVITY; ENZYME PURIFICATION; FETUS; FETUS LIVER; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN TISSUE; LIPID PEROXIDATION; LIVER NECROSIS; MOLECULAR WEIGHT; OXIDATION REDUCTION REACTION; PRENATAL PERIOD; SECOND TRIMESTER PREGNANCY; TARGET CELL DESTRUCTION;

EID: 0042233969     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(03)00220-5     Document Type: Article

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