메뉴 건너뛰기




Volumn 9, Issue 6, 2002, Pages 435-442

Calcium signaling as a molecular target in cancer

Author keywords

Angiogenesis; Invasion; Signal transduction; Tumor growth

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CYTOKINE; IMIDAZOLE; TRIAZOLE; TUMOR MARKER; TYROSINE KINASE RECEPTOR;

EID: 0042193225     PISSN: 1071894X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (5)

References (63)
  • 1
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumor-host invasion field
    • Liotta, L.A. and Kohn, E.C. (2001). The microenvironment of the tumor-host invasion field. Nature 411, 375-379.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 2
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D. and Weinberg, R.A. (2000). The hallmarks of cancer. Cell 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 3
    • 0028944106 scopus 로고
    • Molecular insights into cancer invasion: Strategies for prevention and intervention
    • Kohn, E.C. and Liotta, L.A. (1995). Molecular insights into cancer invasion: strategies for prevention and intervention. Cancer Res 55, 1856-1862.
    • (1995) Cancer Res , vol.55 , pp. 1856-1862
    • Kohn, E.C.1    Liotta, L.A.2
  • 4
    • 0035964367 scopus 로고    scopus 로고
    • Linking molecular therapeutics to molecular diagnostics: Inhibition of the FRAP/RAFT/TOR component of the phosphatidylinositol 3 kinase pathway preferentially blocks PTEN mutant cells in vitro and in vivo
    • Mills, G.B., Lu, Y., and Kohn, E.C. (2001). Linking molecular therapeutics to molecular diagnostics: Inhibition of the FRAP/RAFT/TOR component of the phosphatidylinositol 3 kinase pathway preferentially blocks PTEN mutant cells in vitro and in vivo. Proc Natl Acad Sci USA 98, 10031-10033.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10031-10033
    • Mills, G.B.1    Lu, Y.2    Kohn, E.C.3
  • 5
    • 0023883647 scopus 로고
    • G proteins in clinical medicine
    • Spiegel, A.M. (1988). G proteins in clinical medicine. Hosp Pract (Off Ed) 23, 93-100, 105-106, 111-102.
    • (1988) Hosp Pract (Off Ed) , vol.23 , pp. 93-100
    • Spiegel, A.M.1
  • 6
    • 0027943282 scopus 로고
    • Voltage-independent calcium channels. Regulation by receptors and intracellular calcium stores
    • Felder, C.C., Singer-Lahat, D., and Mathes, C. (1994). Voltage-independent calcium channels. Regulation by receptors and intracellular calcium stores. Biochem Pharmacol, 48, 1997-2004.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1997-2004
    • Felder, C.C.1    Singer-Lahat, D.2    Mathes, C.3
  • 7
    • 0029314844 scopus 로고
    • Calcium signaling and cell proliferation
    • Berridge, M. (1995). Calcium signaling and cell proliferation. Bioessays 17, 491-500.
    • (1995) Bioessays , vol.17 , pp. 491-500
    • Berridge, M.1
  • 8
    • 0030932943 scopus 로고    scopus 로고
    • Elementary and global aspects of calcium signaling
    • Berridge, M.J. (1997). Elementary and global aspects of calcium signaling. Journal of Physiology 499, 290-306.
    • (1997) Journal of Physiology , vol.499 , pp. 290-306
    • Berridge, M.J.1
  • 9
    • 0023118075 scopus 로고
    • Alteration of the tumorigenic and metastatic properties of neoplastic cells is associated with the process of calcium phosphate-mediated DNA transfection
    • Kerbel, R.S., Waghome, C., Man, M.S., Elliott, B., and Breitman, M. L. (1987). Alteration of the tumorigenic and metastatic properties of neoplastic cells is associated with the process of calcium phosphate-mediated DNA transfection. Proc Natl Acad Sci U S A 84, 1263-1267.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 1263-1267
    • Kerbel, R.S.1    Waghome, C.2    Man, M.S.3    Elliott, B.4    Breitman, M.L.5
  • 10
    • 0024346141 scopus 로고
    • Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells
    • Takemura, H., Hughes, A.R., Thastrup, O., and Putney, J.W. (1989). Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. J Biol Chem 264, 12266-12271.
    • (1989) J Biol Chem , vol.264 , pp. 12266-12271
    • Takemura, H.1    Hughes, A.R.2    Thastrup, O.3    Putney, J.W.4
  • 11
    • 0031044227 scopus 로고    scopus 로고
    • Thapsigargin-induced gene expression in non-excitable cells is dependent on calcium influx
    • Rodland, K.D., Wersto, R.P., Hobson, S., and Kohn, E.C. (1997). Thapsigargin-induced gene expression in non-excitable cells is dependent on calcium influx. Mol Endocrinol 11, 281-291.
    • (1997) Mol Endocrinol , vol.11 , pp. 281-291
    • Rodland, K.D.1    Wersto, R.P.2    Hobson, S.3    Kohn, E.C.4
  • 12
    • 0027534894 scopus 로고
    • Tumor-suppressor function of muscarinic acetylcholine receptors is associated with activation of receptor-operated calcium influx
    • Felder, C.C., MacArthur, L., Ma, A.L., Gusovsky, F., and Kohn, E.C. (1993). Tumor-suppressor function of muscarinic acetylcholine receptors is associated with activation of receptor-operated calcium influx. Proc Natl Acad Sci U S A 90, 1706-1710.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 1706-1710
    • Felder, C.C.1    MacArthur, L.2    Ma, A.L.3    Gusovsky, F.4    Kohn, E.C.5
  • 14
    • 0029447016 scopus 로고
    • Stimulation and regulation of tumor cell motility in invasion and metastasis
    • Levine, M.D., Liotta, L.A., and Stracke, M.L. (1995). Stimulation and regulation of tumor cell motility in invasion and metastasis. EXS 74, 157-179.
    • (1995) EXS , vol.74 , pp. 157-179
    • Levine, M.D.1    Liotta, L.A.2    Stracke, M.L.3
  • 15
    • 0027184752 scopus 로고
    • Autocrine motility factor is a growth factor
    • Silletti, S. and Raz, A. (1993). Autocrine motility factor is a growth factor. Biochem Biophys 194, 446-457.
    • (1993) Biochem Biophys , vol.194 , pp. 446-457
    • Silletti, S.1    Raz, A.2
  • 17
    • 0025991235 scopus 로고
    • Comparison of autocrine mechanisms promoting motility in two metastatic cell lines: Human melanoma and ras-transfected NIH3T3 cells
    • Seiki, M., Sato, H., Liotta, L.A., and Schiffmann, E. (1991). Comparison of autocrine mechanisms promoting motility in two metastatic cell lines: human melanoma and ras-transfected NIH3T3 cells. Int J Cancer 49, 717-720.
    • (1991) Int J Cancer , vol.49 , pp. 717-720
    • Seiki, M.1    Sato, H.2    Liotta, L.A.3    Schiffmann, E.4
  • 20
    • 0030044360 scopus 로고    scopus 로고
    • Role of transactivation of the EGF receptro in signalling by G-protien-coupled receptors
    • Daub, H., Weiss, F.U., Wallasch, C., and Ullrich, A. (1996). Role of transactivation of the EGF receptro in signalling by G-protien-coupled receptors. Nature 379, 557-560.
    • (1996) Nature , vol.379 , pp. 557-560
    • Daub, H.1    Weiss, F.U.2    Wallasch, C.3    Ullrich, A.4
  • 21
    • 0021443856 scopus 로고
    • Inositol trisphosphate and diacylglycerol as second messengers
    • Berridge, M.J. (1984). Inositol trisphosphate and diacylglycerol as second messengers. Biochem J 220, 345-360.
    • (1984) Biochem J , vol.220 , pp. 345-360
    • Berridge, M.J.1
  • 23
    • 0033860695 scopus 로고    scopus 로고
    • The EGF receptor: A nexus for trafficking and signaling
    • Carpenter, G. (2000). The EGF receptor: a nexus for trafficking and signaling. Bioessays 22, 697-707.
    • (2000) Bioessays , vol.22 , pp. 697-707
    • Carpenter, G.1
  • 24
    • 0036500831 scopus 로고    scopus 로고
    • Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: A new paradigm for cancer therapy
    • Herbst, R.S. and Shin, D.M. (2002). Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy. Cancer 94, 1593-1611.
    • (2002) Cancer , vol.94 , pp. 1593-1611
    • Herbst, R.S.1    Shin, D.M.2
  • 25
    • 0027412271 scopus 로고
    • Epidermal growth factor-mediated signaling of G(i)-protein to activation of phospholipases in rat-cultured hepatocytes
    • Yang, L., Camoratto, A.M., Baffy, G., Raj, S., Manning, D.R., and Williamson, J.R. (1993). Epidermal growth factor-mediated signaling of G(i)-protein to activation of phospholipases in rat-cultured hepatocytes. J Biol Chem 268, 3739-3746.
    • (1993) J Biol Chem , vol.268 , pp. 3739-3746
    • Yang, L.1    Camoratto, A.M.2    Baffy, G.3    Raj, S.4    Manning, D.R.5    Williamson, J.R.6
  • 26
    • 0023192181 scopus 로고
    • Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell
    • Kadowaki, T., Koyasu, S., Nishida, E., Tobe, K., Izumi, T., Takaku, F., Sakai, H., Yahara, I., and Kasuga, M. (1987). Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell. J Biol Chem 262, 7342-7350.
    • (1987) J Biol Chem , vol.262 , pp. 7342-7350
    • Kadowaki, T.1    Koyasu, S.2    Nishida, E.3    Tobe, K.4    Izumi, T.5    Takaku, F.6    Sakai, H.7    Yahara, I.8    Kasuga, M.9
  • 27
    • 0025144659 scopus 로고
    • Insulin-like growth factor-I stimulates diacylglycerol production via multiple pathways in Balb/c 3T3 cells
    • Kojima, I., Kitaoka, M., and Ogata, E. (1990). Insulin-like growth factor-I stimulates diacylglycerol production via multiple pathways in Balb/c 3T3 cells. J Biol Chem 265, 16846-16850.
    • (1990) J Biol Chem , vol.265 , pp. 16846-16850
    • Kojima, I.1    Kitaoka, M.2    Ogata, E.3
  • 28
    • 0025012854 scopus 로고
    • L651582, a novel anti-proliferative and antimetastasis agent
    • Kohn, E.C. and Liotta, L.A. (1990). L651582, a novel anti-proliferative and antimetastasis agent. J Natl Cancer Inst 82, 54-60.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 54-60
    • Kohn, E.C.1    Liotta, L.A.2
  • 29
    • 0026740712 scopus 로고
    • In vivo efficacy of a novel inhibitor of selected signal transduction pathways including calcium, arachidonate, and inositol phosphates
    • Kohn, E.C., Sandeen, M.A., and Liotta, L.A. (1992). In vivo efficacy of a novel inhibitor of selected signal transduction pathways including calcium, arachidonate, and inositol phosphates. Cancer Res 52, 3208-3212.
    • (1992) Cancer Res , vol.52 , pp. 3208-3212
    • Kohn, E.C.1    Sandeen, M.A.2    Liotta, L.A.3
  • 30
    • 0028205812 scopus 로고
    • Structure-function analysis of signal and growth inhibition by carboxyamido-triazole, CAI
    • Kohn, E.C., Felder, C.C., Jacobs, W., Holmes, K.A., Day, A., Freer, R., and Liotta, L.A. (1994). Structure-function analysis of signal and growth inhibition by carboxyamido-triazole, CAI. Cancer Res 54, 935-942.
    • (1994) Cancer Res , vol.54 , pp. 935-942
    • Kohn, E.C.1    Felder, C.C.2    Jacobs, W.3    Holmes, K.A.4    Day, A.5    Freer, R.6    Liotta, L.A.7
  • 32
    • 0023228346 scopus 로고
    • Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by anti-androgens (flutamide, hydroxyflutamide, RU23908, cyproterone acetate) in vitro
    • Ayub, M., and Levell, M.J. (1987). Inhibition of rat testicular 17 alpha-hydroxylase and 17,20-lyase activities by anti-androgens (flutamide, hydroxyflutamide, RU23908, cyproterone acetate) in vitro. J Steroid Biochem 28, 43-47.
    • (1987) J Steroid Biochem , vol.28 , pp. 43-47
    • Ayub, M.1    Levell, M.J.2
  • 33
    • 0023601787 scopus 로고
    • Inhibition of testicular 17 alpha-hydroxylase and 17,20-lyase but not 3 beta-hydroxysteroid dehydrogenase-isomerase or 17 beta-hydroxysteroid oxidoreductase by ketoconazole and other imidazole drugs
    • Ayub, M., and Levell, M.J. (1987). Inhibition of testicular 17 alpha-hydroxylase and 17,20-lyase but not 3 beta-hydroxysteroid dehydrogenase-isomerase or 17 beta-hydroxysteroid oxidoreductase by ketoconazole and other imidazole drugs. J Steroid Biochem 28, 521-531.
    • (1987) J Steroid Biochem , vol.28 , pp. 521-531
    • Ayub, M.1    Levell, M.J.2
  • 34
    • 0024327180 scopus 로고
    • Nitroimidazole derivatives inhibit anterior pituitary cell function apparently by a direct effect on the catalytic subunit of the adenylate cyclase holoenzyme
    • Stalla, G.K., Stalla, J., von Werder, K., Muller, O.A., Gerzer, R., Hollt, V., and Jakobs, K.H. (1989). Nitroimidazole derivatives inhibit anterior pituitary cell function apparently by a direct effect on the catalytic subunit of the adenylate cyclase holoenzyme. Endocrinology 125, 699-706.
    • (1989) Endocrinology , vol.125 , pp. 699-706
    • Stalla, G.K.1    Stalla, J.2    Von Werder, K.3    Muller, O.A.4    Gerzer, R.5    Hollt, V.6    Jakobs, K.H.7
  • 35
    • 0025782262 scopus 로고
    • Reversal of daunorubicin resistance in P388/ADR cells by itraconazole
    • Gupta, S., Kim, J., and Gollapudi, S. (1991). Reversal of daunorubicin resistance in P388/ADR cells by itraconazole. J Clin Invest 87, 1467-1469.
    • (1991) J Clin Invest , vol.87 , pp. 1467-1469
    • Gupta, S.1    Kim, J.2    Gollapudi, S.3
  • 36
    • 0026347077 scopus 로고
    • Comparative studies of steroidogenesis inhibitors (econazole, ketoconazole) on human breast cancer MCF-7 cell proliferation by growth experiments, thymidine incorporation and flow cytometric DNA analysis
    • Najid, A. and Ratinaud, M.H. (1991). Comparative studies of steroidogenesis inhibitors (econazole, ketoconazole) on human breast cancer MCF-7 cell proliferation by growth experiments, thymidine incorporation and flow cytometric DNA analysis. Tumori 77, 385-390.
    • (1991) Tumori , vol.77 , pp. 385-390
    • Najid, A.1    Ratinaud, M.H.2
  • 37
    • 0034769376 scopus 로고    scopus 로고
    • Effects of azoles on human acute myelogenous leukemia blasts and T lymphocytes derived from acute leukemia patients with chemotherapy-induced cytopenia
    • Bruserud, O. (2001). Effects of azoles on human acute myelogenous leukemia blasts and T lymphocytes derived from acute leukemia patients with chemotherapy-induced cytopenia. Int Immunopharmacol 1, 2183-2195.
    • (2001) Int Immunopharmacol , vol.1 , pp. 2183-2195
    • Bruserud, O.1
  • 38
    • 0027439833 scopus 로고
    • Control of Ca2+ entry into HL60 and U937 human leukaemia cells by the filling state of the intracellular Ca2+ stores
    • Alonso-Torre, S.R., Alvarez, J., Montero, M., Sanchez, A., and Garcia-Sancho, J. (1993). Control of Ca2+ entry into HL60 and U937 human leukaemia cells by the filling state of the intracellular Ca2+ stores. Biochem J 289:761-766.
    • (1993) Biochem J , vol.289 , pp. 761-766
    • Alonso-Torre, S.R.1    Alvarez, J.2    Montero, M.3    Sanchez, A.4    Garcia-Sancho, J.5
  • 39
    • 0026729362 scopus 로고
    • Inhibition of voltage-gated Ca2+ entry into GH3 and chromaffin cells by imidazole antimycotics and other cytochrome P450 blockers
    • Villalobos, C., Fonteriz, R., Lopez, M.G., Garcia, A.G., and Garcia-Sancho, J. (1992). Inhibition of voltage-gated Ca2+ entry into GH3 and chromaffin cells by imidazole antimycotics and other cytochrome P450 blockers. FASEB J 6, 2742-2747.
    • (1992) FASEB J , vol.6 , pp. 2742-2747
    • Villalobos, C.1    Fonteriz, R.2    Lopez, M.G.3    Garcia, A.G.4    Garcia-Sancho, J.5
  • 41
    • 0030070894 scopus 로고    scopus 로고
    • Clotrimazole and efaroxan inhibit red cell Gardos channel independently of imidazoline I1 and I2 binding sites
    • Coupry, I., Armsby, C.C., Alper, S.L., Brugnara, C., and Parini, A. (1996). Clotrimazole and efaroxan inhibit red cell Gardos channel independently of imidazoline I1 and I2 binding sites. Eur J Pharmacol 2295, 109-112.
    • (1996) Eur J Pharmacol , vol.2295 , pp. 109-112
    • Coupry, I.1    Armsby, C.C.2    Alper, S.L.3    Brugnara, C.4    Parini, A.5
  • 42
    • 0028944824 scopus 로고
    • Oral administration of clotrimazole and blockade of human erythrocyte Ca(++)-activated K+ channel: The imidazole ring is not required for inhibitory activity
    • Brugnara, C., Armsby, C.C., Sakamoto, M., Rifai, N., Alper, S.L., and Platt, O. (1995). Oral administration of clotrimazole and blockade of human erythrocyte Ca(++)-activated K+ channel: the imidazole ring is not required for inhibitory activity. J Pharmacol Exp Ther 273, 266-272.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 266-272
    • Brugnara, C.1    Armsby, C.C.2    Sakamoto, M.3    Rifai, N.4    Alper, S.L.5    Platt, O.6
  • 43
    • 0026598916 scopus 로고
    • Cytochrome P450 may regulate plasma membrane Ca2+ permeability according to the filling state of the intracellular Ca2+ stores
    • Alvarez, J., Montero, M., and Garcia-Sancho, J. (1992). Cytochrome P450 may regulate plasma membrane Ca2+ permeability according to the filling state of the intracellular Ca2+ stores. FASEB J 6, 786-792.
    • (1992) FASEB J , vol.6 , pp. 786-792
    • Alvarez, J.1    Montero, M.2    Garcia-Sancho, J.3
  • 44
    • 0026795792 scopus 로고
    • Calcium influx evoked by Ca2+ store depletion in human platelets is more susceptible to cytochrome P-450 inhibitors than receptor-mediated calcium entry
    • Sargeant, P., Clarkson, W.D., Sage, S.O., and Heemskerk, J.W. (1992). Calcium influx evoked by Ca2+ store depletion in human platelets is more susceptible to cytochrome P-450 inhibitors than receptor-mediated calcium entry. Cell Calcium 13, 553-564.
    • (1992) Cell Calcium , vol.13 , pp. 553-564
    • Sargeant, P.1    Clarkson, W.D.2    Sage, S.O.3    Heemskerk, J.W.4
  • 45
    • 0026338011 scopus 로고
    • Agonist-induced Ca2+ influx into human platelets is secondary to the emptying of intracellular Ca2+ stores
    • Alonso, M.T., Alvarez, J., Montero, M., Sanchez, A., and Garcia-Sancho, J. (1991). Agonist-induced Ca2+ influx into human platelets is secondary to the emptying of intracellular Ca2+ stores. Biochem J 280, 783-789.
    • (1991) Biochem J , vol.280 , pp. 783-789
    • Alonso, M.T.1    Alvarez, J.2    Montero, M.3    Sanchez, A.4    Garcia-Sancho, J.5
  • 46
    • 0028945544 scopus 로고
    • Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo
    • Ludden, L.K., Strong, J.M., Kohn, E.C., and Collins, J.M. (1995). Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo. Clin Cancer Research 1, 399-405.
    • (1995) Clin Cancer Research , vol.1 , pp. 399-405
    • Ludden, L.K.1    Strong, J.M.2    Kohn, E.C.3    Collins, J.M.4
  • 48
    • 0036010918 scopus 로고    scopus 로고
    • Purging of contaminating breast cancer cells from hematopoietic progenitor cell preparations using activation enhanced cell death
    • Zhang, Y., Crump, M., and Berge, S.A. (2002). Purging of contaminating breast cancer cells from hematopoietic progenitor cell preparations using activation enhanced cell death. Breast Cancer Res Treat 72, 265-278.
    • (2002) Breast Cancer Res Treat , vol.72 , pp. 265-278
    • Zhang, Y.1    Crump, M.2    Berge, S.A.3
  • 49
    • 0025772585 scopus 로고
    • The antiproliferative and antimetastatic compound L651582, inhibits muscarinic acetylcholine receptor-stimulated calcium influx and arachidonic acid release
    • Felder, C.C., Ma, A.L., Liotta, L.A., and Kohn, E.C. (1991). The antiproliferative and antimetastatic compound L651582, inhibits muscarinic acetylcholine receptor-stimulated calcium influx and arachidonic acid release. J Pharmacol Exp Ther 257, 967-971.
    • (1991) J Pharmacol Exp Ther , vol.257 , pp. 967-971
    • Felder, C.C.1    Ma, A.L.2    Liotta, L.A.3    Kohn, E.C.4
  • 50
    • 0027503305 scopus 로고
    • Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma: Alternative mechanism for cholinergic receptor-induced phosphoinositide breakdown
    • Gusovsky, F., Lueders, J.E., Kohn, E.C., and Felder, C.C. (1993). Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma: alternative mechanism for cholinergic receptor-induced phosphoinositide breakdown. J Biol Chem 268, 7768-7772.
    • (1993) J Biol Chem , vol.268 , pp. 7768-7772
    • Gusovsky, F.1    Lueders, J.E.2    Kohn, E.C.3    Felder, C.C.4
  • 51
    • 0028040432 scopus 로고
    • Calcium influx regulates matrix metalloproteinase-2 (72 kDa type IV collagenase, gelatinase A) expression
    • Kohn, E.C., Jacobs, W., Kim, Y.S., Alessandro, R., Stetler-Stevenson, W.G., and Liotta, L.A. (1994). Calcium influx regulates matrix metalloproteinase-2 (72 kDa type IV collagenase, gelatinase A) expression. J Biol Chem 269, 21505-21511.
    • (1994) J Biol Chem , vol.269 , pp. 21505-21511
    • Kohn, E.C.1    Jacobs, W.2    Kim, Y.S.3    Alessandro, R.4    Stetler-Stevenson, W.G.5    Liotta, L.A.6
  • 54
    • 0030788471 scopus 로고    scopus 로고
    • Regulation of cell spreading during differentiation in the muscarinic m5 receptor tumor suppressor model
    • Spoonster, J.R., Masiero, L., Savage, S.A., Probst, J., and Kohn, E.C. (1997). Regulation of cell spreading during differentiation in the muscarinic m5 receptor tumor suppressor model. Int J Cancer 72, 362-368.
    • (1997) Int J Cancer , vol.72 , pp. 362-368
    • Spoonster, J.R.1    Masiero, L.2    Savage, S.A.3    Probst, J.4    Kohn, E.C.5
  • 57
    • 0032581417 scopus 로고    scopus 로고
    • Endothelial cell spreading on type IV collagen and spreading induced FAK phosphorylation is regulated by calcium influx
    • Alessandro, R., Masiero, L., Lapidos, K., Spoonster, J., and Kohn, E.C. (1998). Endothelial cell spreading on type IV collagen and spreading induced FAK phosphorylation is regulated by calcium influx. Biochem Biophys Res Commun 248, 635-640.
    • (1998) Biochem Biophys Res Commun , vol.248 , pp. 635-640
    • Alessandro, R.1    Masiero, L.2    Lapidos, K.3    Spoonster, J.4    Kohn, E.C.5
  • 58
    • 0032746309 scopus 로고    scopus 로고
    • Regulation of the RhoA$pathway in human endothelial cell spreading on type IV collagen: Role of calcium influx
    • Masiero, L., Lapidos, K.A., Ambudkar, I., and Kohn, E.C. (1999). Regulation of the RhoA$pathway in human endothelial cell spreading on type IV collagen: role of calcium influx. Journal Cell Sci 112, 3205-3213.
    • (1999) Journal Cell Sci , vol.112 , pp. 3205-3213
    • Masiero, L.1    Lapidos, K.A.2    Ambudkar, I.3    Kohn, E.C.4
  • 59
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld, G., Cohen, T., Gengrinovitch, S., and Poltorak, Z. (1999). Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 13, 9-22.
    • (1999) FASEB J , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 61
    • 0030991528 scopus 로고    scopus 로고
    • Phase I trial of micronized formulation CAI in patients with refractory solid tumors: Pharmacokinetics, clinical outcome and comparison of formulations
    • Kohn, E.C., Figg, W.D., Sarosy, G.A., Bauer, K.S., Davis, P.A., Soltis, M.J., Thompkins, A., Liotta, L.A., and Reed, E. (1997). Phase I trial of micronized formulation CAI in patients with refractory solid tumors: pharmacokinetics, clinical outcome and comparison of formulations. Journal Clin Oncol 15, 1985-1993.
    • (1997) Journal Clin Oncol , vol.15 , pp. 1985-1993
    • Kohn, E.C.1    Figg, W.D.2    Sarosy, G.A.3    Bauer, K.S.4    Davis, P.A.5    Soltis, M.J.6    Thompkins, A.7    Liotta, L.A.8    Reed, E.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.