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Volumn 15, Issue 5, 1997, Pages 1985-1993

Phase I trial of micronized formulation carboxyamidotriazole in patients with refractory solid tumors: Pharmacokinetics, clinical outcome, and comparison of formulations

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 1 [3,5 DICHLORO 4 (4 CHLOROBENZOYL)BENZYL] 1H 1,2,3 TRIAZOLE 4 CARBOXAMIDE; UNCLASSIFIED DRUG;

EID: 0030991528     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1997.15.5.1985     Document Type: Article
Times cited : (67)

References (22)
  • 1
    • 0029314844 scopus 로고
    • Calcium signalling and cell proliferation
    • Berridge MJ: Calcium signalling and cell proliferation. Bioessays 17:491-500, 1995
    • (1995) Bioessays , vol.17 , pp. 491-500
    • Berridge, M.J.1
  • 2
    • 0028009848 scopus 로고
    • Calcium-mediated signal transduction: Biology, biochemistry, and therapy
    • Cole KA, Kohn EC: Calcium-mediated signal transduction: Biology, biochemistry, and therapy. Cancer Met Rev 13:33-41, 1994
    • (1994) Cancer Met Rev , vol.13 , pp. 33-41
    • Cole, K.A.1    Kohn, E.C.2
  • 4
    • 0025012854 scopus 로고
    • L651582, a novel antiproliferative and antimetastasis agent
    • Kohn EC, Liotta LA: L651582, a novel antiproliferative and antimetastasis agent. J Natl Cancer Inst 82:54-60, 1990
    • (1990) J Natl Cancer Inst , vol.82 , pp. 54-60
    • Kohn, E.C.1    Liotta, L.A.2
  • 5
    • 0026740712 scopus 로고
    • In vivo efficacy of a novel inhibitor of selected signal transduction pathways including calcium, arachidonate, and inositol phosphates
    • Kohn EC, Sandeen MA, Liotta LA: In vivo efficacy of a novel inhibitor of selected signal transduction pathways including calcium, arachidonate, and inositol phosphates. Cancer Res 52:3208-3212, 1992
    • (1992) Cancer Res , vol.52 , pp. 3208-3212
    • Kohn, E.C.1    Sandeen, M.A.2    Liotta, L.A.3
  • 6
    • 0028913347 scopus 로고
    • Angiogenesis: Role of calcium-mediated signal transduction
    • Kohn EC, Alessandro R, Spoonster J, et al: Angiogenesis: Role of calcium-mediated signal transduction. Proc Natl Acad Sci USA 92:1307-1311, 1995
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1307-1311
    • Kohn, E.C.1    Alessandro, R.2    Spoonster, J.3
  • 7
    • 0025772585 scopus 로고
    • The antiproliferative and antimetastatic compound L651582, inhibits muscarinic acetylcholine receptor-stimulated calcium influx and arachidonic acid release
    • Felder CC, Ma AL, Liotta LA, et al: The antiproliferative and antimetastatic compound L651582, inhibits muscarinic acetylcholine receptor-stimulated calcium influx and arachidonic acid release. J Pharm Exp Ther 257:967-971, 1991
    • (1991) J Pharm Exp Ther , vol.257 , pp. 967-971
    • Felder, C.C.1    Ma, A.L.2    Liotta, L.A.3
  • 8
    • 0027503305 scopus 로고
    • Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma: Alternative mechanism for cholinergic receptor-induced phosphoinositide breakdown
    • Gusovsky F, Lueders JE, Kohn EC, et al: Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma: Alternative mechanism for cholinergic receptor-induced phosphoinositide breakdown. J Biol Chem 268:7768-7772, 1993
    • (1993) J Biol Chem , vol.268 , pp. 7768-7772
    • Gusovsky, F.1    Lueders, J.E.2    Kohn, E.C.3
  • 9
    • 0025912644 scopus 로고
    • The inhibition of receptor-mediated and voltage-dependent calcium entry by the antiproliferative L-651,582
    • Hupe DJ, Boltz R, Cohen CJ, et al: The inhibition of receptor-mediated and voltage-dependent calcium entry by the antiproliferative L-651,582. J Biol Chem 266:10136-10142, 1991
    • (1991) J Biol Chem , vol.266 , pp. 10136-10142
    • Hupe, D.J.1    Boltz, R.2    Cohen, C.J.3
  • 10
    • 0028205812 scopus 로고
    • Stucture function analysis of signal and growth inhibition by carboxyamido-triazole, CAI
    • Kohn EC, Felder CC, Jacobs W, et al: Stucture function analysis of signal and growth inhibition by carboxyamido-triazole, CAI. Cancer Res 54:935-942, 1994
    • (1994) Cancer Res , vol.54 , pp. 935-942
    • Kohn, E.C.1    Felder, C.C.2    Jacobs, W.3
  • 12
    • 9044229717 scopus 로고    scopus 로고
    • Clinical investigation of a cytostatic calcium influx inhibitor in patients with refractory cancers
    • Kohn EC, Reed E, Sarosy E, et al: Clinical investigation of a cytostatic calcium influx inhibitor in patients with refractory cancers. Cancer Res 56:569-573, 1996
    • (1996) Cancer Res , vol.56 , pp. 569-573
    • Kohn, E.C.1    Reed, E.2    Sarosy, E.3
  • 13
    • 0029116458 scopus 로고
    • Pharmacokinetics of orally administered carboxyamidotriazole (CAI), an inhibitor of calcium-mediated signal transduction
    • Figg WD, Cole KA, Reed E, et al: Pharmacokinetics of orally administered carboxyamidotriazole (CAI), an inhibitor of calcium-mediated signal transduction. Clin Cancer Res 1:797-803, 1995
    • (1995) Clin Cancer Res , vol.1 , pp. 797-803
    • Figg, W.D.1    Cole, K.A.2    Reed, E.3
  • 14
    • 0018387530 scopus 로고
    • A program package for simulation and parameter estimation in pharmacokinetic systems
    • D'Argenia DZ, Schumitzky A: A program package for simulation and parameter estimation in pharmacokinetic systems. Comp Prog Biomed 9:115-134, 1979
    • (1979) Comp Prog Biomed , vol.9 , pp. 115-134
    • D'Argenia, D.Z.1    Schumitzky, A.2
  • 15
    • 0018091195 scopus 로고
    • Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations
    • Yamaoka K, Nakagawa J, Uno T: Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations. J Pharmacokinet Biop 2:165-175, 1978
    • (1978) J Pharmacokinet Biop , vol.2 , pp. 165-175
    • Yamaoka, K.1    Nakagawa, J.2    Uno, T.3
  • 17
    • 0028006219 scopus 로고
    • Commentary: Rethinking cancer
    • Astrow AB: Commentary: Rethinking cancer. Lancet 343: 494-495, 1994
    • (1994) Lancet , vol.343 , pp. 494-495
    • Astrow, A.B.1
  • 18
    • 0028097472 scopus 로고
    • Pharmaceutical research in molecular oncology
    • Gibbs JB, Oliff A: Pharmaceutical research in molecular oncology. Cell 79:193-198, 1994
    • (1994) Cell , vol.79 , pp. 193-198
    • Gibbs, J.B.1    Oliff, A.2
  • 19
    • 0028913573 scopus 로고
    • Shifting the cancer paradigm: Must we kill to cure?
    • Schipper H, Goh CR, Wang TL: Shifting the cancer paradigm: Must we kill to cure? J Clin Oncol 13:801-807, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 801-807
    • Schipper, H.1    Goh, C.R.2    Wang, T.L.3
  • 20
    • 0028040432 scopus 로고
    • Calcium influx modulates expression of matrix metalloproteinase-2 (72 kDa type IV collagenase, gelatinase A) expression
    • Kohn EC, Jacobs W, Kim YS, et al: Calcium influx modulates expression of matrix metalloproteinase-2 (72 kDa type IV collagenase, gelatinase A) expression. J Biol Chem 269:21505-21511, 1994
    • (1994) J Biol Chem , vol.269 , pp. 21505-21511
    • Kohn, E.C.1    Jacobs, W.2    Kim, Y.S.3
  • 21
    • 0028944106 scopus 로고
    • Molecular insights into cancer invasion: Strategies for prevention and intervention
    • Kohn EC, Liotta LA: Molecular insights into cancer invasion: Strategies for prevention and intervention. Cancer Res 55:1856-1862, 1995
    • (1995) Cancer Res , vol.55 , pp. 1856-1862
    • Kohn, E.C.1    Liotta, L.A.2
  • 22
    • 0029819854 scopus 로고    scopus 로고
    • Signal transduction therapy for prostate cancer: Sensitivities of human prostate tumor cell lines to the calcium influx inhibitor carboxyamido-triazole
    • Wasilenko WJ, Palad AJ, Somers KD, et al: Signal transduction therapy for prostate cancer: Sensitivities of human prostate tumor cell lines to the calcium influx inhibitor carboxyamido-triazole. Int J Cancer 68:259-264, 1996
    • (1996) Int J Cancer , vol.68 , pp. 259-264
    • Wasilenko, W.J.1    Palad, A.J.2    Somers, K.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.