Dissecting interdomain communication within cAPK regulatory subunit type IIβ using enhanced amide hydrogen/deuterium exchange mass spectrometry (DXMS)

Protein Science

Volumn 12, Issue 9, 2003, Pages 1980-1990

  Zawadzki, Kerri M ^a   Hamuro, Yoshitomo ^a,c   Kim, Jack S ^a   Garrod, Siv ^a   Stranz, David D ^b   Taylor, Susan S ^a   Woods Jr , Virgil L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Sierra Analytics LLC   (United States)

^c ExSAR Corporation   (United States)

Author keywords

Amide hydrogen exchange; cAPK; Mass spectrometry; PKA; Regulatory subunit

Indexed keywords

AMIDE; ARGININE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIMER; LYSINE; MUTANT PROTEIN; PROTEIN SUBUNIT; REGULATOR PROTEIN;

ALLOSTERISM; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; DEUTERIUM EXCHANGE MASS SPECTROMETRY; DYNAMICS; ENZYME ACTIVATION; ENZYME BINDING; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; REGULATORY MECHANISM;

ALLOSTERIC SITE; AMINO ACID SEQUENCE; ARGININE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DEUTERIUM; DIMERIZATION; ESCHERICHIA COLI; HYDROGEN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TIME FACTORS;

EID: 0042010184     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.03166903     Document Type: Article

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