-
1
-
-
0036533649
-
Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
-
Asokananthan N, Graham PT, Fink J, Knight DA, Bakker AJ, McWilliam AS, Thompson PJ Stewart GA. 2002. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J Immunol 168:3577-3585.
-
(2002)
J Immunol
, vol.168
, pp. 3577-3585
-
-
Asokananthan, N.1
Graham, P.T.2
Fink, J.3
Knight, D.A.4
Bakker, A.J.5
McWilliam, A.S.6
Thompson, P.J.7
Stewart, G.A.8
-
2
-
-
0018932068
-
Protease-nexin: A cellular component that links thrombin and plasminogen activator and mediates their binding to cells
-
Baker JB, Low DA, Simmer RL, Cunningham DD. 1980. Protease-nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells. Cell 21:37-45.
-
(1980)
Cell
, vol.21
, pp. 37-45
-
-
Baker, J.B.1
Low, D.A.2
Simmer, R.L.3
Cunningham, D.D.4
-
3
-
-
0022632088
-
Collagenase activity in skin fibroblasts of patients with amyotrophic lateral sclerosis
-
Beach RL, Rao JS, Festoff BW, Reyes ET, Yanagihara R, Gajdusek DC. 1986. Collagenase activity in skin fibroblasts of patients with amyotrophic lateral sclerosis. J Neurol Sci 72:49-60.
-
(1986)
J Neurol Sci
, vol.72
, pp. 49-60
-
-
Beach, R.L.1
Rao, J.S.2
Festoff, B.W.3
Reyes, E.T.4
Yanagihara, R.5
Gajdusek, D.C.6
-
4
-
-
0028085095
-
Thrombin receptor peptides induce shape change in neonatal murine astrocytes in culture
-
Beecher KL, Andersen TT, Fenton JW 2nd, Festoff BW. 1994. Thrombin receptor peptides induce shape change in neonatal murine astrocytes in culture. J Neurosci Res 37:108-115.
-
(1994)
J Neurosci Res
, vol.37
, pp. 108-115
-
-
Beecher, K.L.1
Andersen, T.T.2
Fenton J.W. II3
Festoff, B.W.4
-
5
-
-
0029072476
-
Exogenous thrombin inhibits neuritogenesis in cultured neuroblastoma cells but not in rat hippocampal neurons
-
Brewer GJ. 1995. Exogenous thrombin inhibits neuritogenesis in cultured neuroblastoma cells but not in rat hippocampal neurons. Brain Res 683:258-263.
-
(1995)
Brain Res
, vol.683
, pp. 258-263
-
-
Brewer, G.J.1
-
6
-
-
0029938079
-
Thrombin causes cell spreading and redistribution of beta-amyloid immunoreactivity in cultured hippocampal neurons
-
Brewer GJ. 1996. Thrombin causes cell spreading and redistribution of beta-amyloid immunoreactivity in cultured hippocampal neurons. J Neurochem 67:119-130.
-
(1996)
J Neurochem
, vol.67
, pp. 119-130
-
-
Brewer, G.J.1
-
7
-
-
0037341150
-
Thrombin induces in vivo degeneration of nigral dopaminergic neurones along with the activation of microglia
-
Carreno-Muller E, Herrera AJ, de Pablos RM, Tomas-Camardiel M, Venero JL, Cano J, Machado A. 2003. Thrombin induces in vivo degeneration of nigral dopaminergic neurones along with the activation of microglia. J Neurochem 84:1201-1214.
-
(2003)
J Neurochem
, vol.84
, pp. 1201-1214
-
-
Carreno-Muller, E.1
Herrera, A.J.2
De Pablos, R.M.3
Tomas-Camardiel, M.4
Venero, J.L.5
Cano, J.6
Machado, A.7
-
8
-
-
0025255579
-
Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1
-
Cavanaugh KP, Gurwitz D, Cunningham DD, Bradshaw RA. 1990. Reciprocal modulation of astrocyte stellation by thrombin and protease nexin-1. J Neurochem 54:1735-1743.
-
(1990)
J Neurochem
, vol.54
, pp. 1735-1743
-
-
Cavanaugh, K.P.1
Gurwitz, D.2
Cunningham, D.D.3
Bradshaw, R.A.4
-
9
-
-
0034194405
-
Inflammation-coagulation network: Are serine protease receptors the knot?
-
Cirino G, Napoli C, Bucci M, Cicala C. 2000. Inflammation-coagulation network: are serine protease receptors the knot? Trends Pharmacol Sci 21:170-172.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 170-172
-
-
Cirino, G.1
Napoli, C.2
Bucci, M.3
Cicala, C.4
-
10
-
-
0030868155
-
Quantitative PCR analysis reveals novel expression of prothrombin mRNA and regulation of its levels in developing mouse muscle
-
Citron BA, Smirnova IV, Zoubine MN, Festoff BW: 1997a. Quantitative PCR analysis reveals novel expression of prothrombin mRNA and regulation of its levels in developing mouse muscle. Thromb Res 87:303-313.
-
(1997)
Thromb Res
, vol.87
, pp. 303-313
-
-
Citron, B.A.1
Smirnova, I.V.2
Zoubine, M.N.3
Festoff, B.W.4
-
11
-
-
0031564833
-
Apoptotic, injury-induced cell death in cultured mouse murine motor neurons
-
Citron BA, Zhang SX, Smirnova IV, Festoff BW. 1997b. Apoptotic, injury-induced cell death in cultured mouse murine motor neurons. Neurosci Lett 230:25-28.
-
(1997)
Neurosci Lett
, vol.230
, pp. 25-28
-
-
Citron, B.A.1
Zhang, S.X.2
Smirnova, I.V.3
Festoff, B.W.4
-
12
-
-
0033662889
-
Upregulation of neurotoxic serine proteases, prothrombin, and protease-activated receptor 1 early after spinal cord injury
-
Citron BA, Smirnova IV, Arnold PM, Festoff BW. 2000. Upregulation of neurotoxic serine proteases, prothrombin, and protease-activated receptor 1 early after spinal cord injury. J Neurotrauma 17:1191-1203.
-
(2000)
J Neurotrauma
, vol.17
, pp. 1191-1203
-
-
Citron, B.A.1
Smirnova, I.V.2
Arnold, P.M.3
Festoff, B.W.4
-
13
-
-
0034161592
-
Protease-activated receptors: Sentries for inflammation?
-
Cocks TM, Moffatt JD. 2000. Protease-activated receptors: sentries for inflammation? Trends Pharmacol Sci 21:103-108.
-
(2000)
Trends Pharmacol Sci
, vol.21
, pp. 103-108
-
-
Cocks, T.M.1
Moffatt, J.D.2
-
14
-
-
0030008312
-
Role of the thrombin receptor in development and evidence for a second receptor
-
Connolly AJ, Ishihara H, Kahn ML, Farese RV Jr, Coughlin SR. 1996. Role of the thrombin receptor in development and evidence for a second receptor. Nature 381:516-519.
-
(1996)
Nature
, vol.381
, pp. 516-519
-
-
Connolly, A.J.1
Ishihara, H.2
Kahn, M.L.3
Farese R.V., Jr.4
Coughlin, S.R.5
-
15
-
-
0034921205
-
Protease-activated receptors in vascular biology
-
Coughlin SR. 2001. Protease-activated receptors in vascular biology. Thromb Haemost 86:298-307.
-
(2001)
Thromb Haemost
, vol.86
, pp. 298-307
-
-
Coughlin, S.R.1
-
17
-
-
0028979722
-
[Ca2+]i oscillations in single rat glioma cells induced by thrombin through activation of cell surface receptors
-
Czubayko U, Reiser G. 1995. [Ca2+]i oscillations in single rat glioma cells induced by thrombin through activation of cell surface receptors. Neuroreport 6:1249-1252.
-
(1995)
Neuroreport
, vol.6
, pp. 1249-1252
-
-
Czubayko, U.1
Reiser, G.2
-
18
-
-
8044253419
-
Biological consequences of thrombin receptor deficiency in mice
-
Darrow AL, Fung-Leung WP, Ye RD, Santulli RJ, Cheung WM, Derian CK, Burns CL, Damiano BP, Zhou L, Keenan CM, Peterson PA, Andrade-Gordon P. 1996. Biological consequences of thrombin receptor deficiency in mice. Thromb Haemost 76:860-866.
-
(1996)
Thromb Haemost
, vol.76
, pp. 860-866
-
-
Darrow, A.L.1
Fung-Leung, W.P.2
Ye, R.D.3
Santulli, R.J.4
Cheung, W.M.5
Derian, C.K.6
Burns, C.L.7
Damiano, B.P.8
Zhou, L.9
Keenan, C.M.10
Peterson, P.A.11
Andrade-Gordon, P.12
-
19
-
-
0033014958
-
Proteinase-activated receptors: A growing family of heptahelical receptors for thrombin, trypsin and tryptase
-
Dery O, Bunnett NW. 1999. Proteinase-activated receptors: a growing family of heptahelical receptors for thrombin, trypsin and tryptase. Biochem Soc Trans 27:246-254.
-
(1999)
Biochem Soc Trans
, vol.27
, pp. 246-254
-
-
Dery, O.1
Bunnett, N.W.2
-
20
-
-
0025857712
-
Prothrombin mRNA is expressed by cells of the nervous system
-
Dihanich M, Kaser M, Reinhard E, Cunningham D, Monard D. 1991. Prothrombin mRNA is expressed by cells of the nervous system. Neuron 6:575-581.
-
(1991)
Neuron
, vol.6
, pp. 575-581
-
-
Dihanich, M.1
Kaser, M.2
Reinhard, E.3
Cunningham, D.4
Monard, D.5
-
21
-
-
0032557654
-
Signaling pathways involved in thrombin-induced cell protection
-
Donovan FM, Cunningham DD. 1998. Signaling pathways involved in thrombin-induced cell protection. J Biol Chem 273:12746-12752.
-
(1998)
J Biol Chem
, vol.273
, pp. 12746-12752
-
-
Donovan, F.M.1
Cunningham, D.D.2
-
22
-
-
0018326133
-
Neurotrophic control of 16S acetylcholinesterase at the vertebrate neuromuscular junction
-
Fernandez HL, Duell MJ, Festoff BW. 1979. Neurotrophic control of 16S acetylcholinesterase at the vertebrate neuromuscular junction. J Neurobiol 10:441-454.
-
(1979)
J Neurobiol
, vol.10
, pp. 441-454
-
-
Fernandez, H.L.1
Duell, M.J.2
Festoff, B.W.3
-
23
-
-
0018876727
-
Neuromuscular junction macromolecules in the pathogenesis of amyotrophic lateral sclerosis
-
Festoff BW. 1980. Neuromuscular junction macromolecules in the pathogenesis of amyotrophic lateral sclerosis. Med Hypotheses 6:121-131.
-
(1980)
Med Hypotheses
, vol.6
, pp. 121-131
-
-
Festoff, B.W.1
-
24
-
-
0023075339
-
Proteases, their inhibitors and the extracellular matrix: Factors in nerve-muscle development and maintenance
-
Festoff BW. 1987. Proteases, their inhibitors and the extracellular matrix: factors in nerve-muscle development and maintenance. Adv Exp Med Biol 209:25-39.
-
(1987)
Adv Exp Med Biol
, vol.209
, pp. 25-39
-
-
Festoff, B.W.1
-
25
-
-
0000028974
-
Clinical potential of agents that affect thrombin signaling in degenerative and traumatic neurologic disorders
-
Mattson MP, ed, Totowa, NJ: Humana Press
-
Festoff BW. 1997. Clinical potential of agents that affect thrombin signaling in degenerative and traumatic neurologic disorders. In: Mattson MP, ed. Neuroprotective signal transduction, Totowa, NJ: Humana Press. p 221-241.
-
(1997)
Neuroprotective Signal Transduction
, pp. 221-241
-
-
Festoff, B.W.1
-
26
-
-
0023611560
-
Plasminogen activators and inhibitors: Roles in muscle and neuromuscular regeneration
-
Festoff BW, Hantaï D. 1987. Plasminogen activators and inhibitors: roles in muscle and neuromuscular regeneration. Progr Brain Res 71:423-431.
-
(1987)
Progr Brain Res
, vol.71
, pp. 423-431
-
-
Festoff, B.W.1
Hantaï, D.2
-
27
-
-
0020077984
-
Plasminogen activator: The major secreted neutral protease of cultured skeletal muscle cells
-
Festoff BW, Patterson MR, Romstedt K. 1982. Plasminogen activator: the major secreted neutral protease of cultured skeletal muscle cells. J Cell Physiol 110:90-195.
-
(1982)
J Cell Physiol
, vol.110
, pp. 90-195
-
-
Festoff, B.W.1
Patterson, M.R.2
Romstedt, K.3
-
28
-
-
0023024927
-
Plasminogen activator in mammalian skeletal muscle: Characteristics of effect of denervation on urokinase-like and tissue activator
-
Festoff BW, Hantaï D, Soria J, Thomaidis A, Soria C. 1986. Plasminogen activator in mammalian skeletal muscle: characteristics of effect of denervation on urokinase-like and tissue activator. J Cell Biol 103:1415-1421.
-
(1986)
J Cell Biol
, vol.103
, pp. 1415-1421
-
-
Festoff, B.W.1
Hantaï, D.2
Soria, J.3
Thomaidis, A.4
Soria, C.5
-
29
-
-
0025877805
-
Plasminogen activators and inhibitors in the neuromuscular system: III. The serpin protease nexin I is synthesized by muscle and localized at neuromuscular synapses
-
Festoff BW, Bao JS, Hantaï D. 1991. Plasminogen activators and inhibitors in the neuromuscular system: III. The serpin protease nexin I is synthesized by muscle and localized at neuromuscular synapses. J Cell Physiol 147:76-86.
-
(1991)
J Cell Physiol
, vol.147
, pp. 76-86
-
-
Festoff, B.W.1
Bao, J.S.2
Hantaï, D.3
-
30
-
-
0029948143
-
Prevention of activity-dependent neuronal death: Vasoactive intestinal polypeptide stimulates astrocytes to secrete the thrombin-inhibiting neurotrophic serpin protease nexin 1
-
Festoff BW, Nelson PG, Brenneman DE. 1996. Prevention of activity-dependent neuronal death: vasoactive intestinal polypeptide stimulates astrocytes to secrete the thrombin-inhibiting neurotrophic serpin protease nexin 1. J Neurobiol 30:255-266.
-
(1996)
J Neurobiol
, vol.30
, pp. 255-266
-
-
Festoff, B.W.1
Nelson, P.G.2
Brenneman, D.E.3
-
31
-
-
0034186091
-
Motor neuron cell death in wobbler mutant mice follows overexpression of the G-protein-coupled, protease-activated receptor for thrombin
-
Festoff BW, D'Andrea MR, Citron BA, Salcedo RM, Smirnova IV, Andrade-Gordon P. 2000. Motor neuron cell death in wobbler mutant mice follows overexpression of the G-protein-coupled, protease-activated receptor for thrombin. Mol Med 6:410-429.
-
(2000)
Mol Med
, vol.6
, pp. 410-429
-
-
Festoff, B.W.1
D'Andrea, M.R.2
Citron, B.A.3
Salcedo, R.M.4
Smirnova, I.V.5
Andrade-Gordon, P.6
-
32
-
-
0035167784
-
Inflammo-coagulatory response, extrinsic pathway thrombin generation and a new theory of activated clotting time interpretation
-
Gil W. 2001. Inflammo-coagulatory response, extrinsic pathway thrombin generation and a new theory of activated clotting time interpretation. Perfusion 16:27-35.
-
(2001)
Perfusion
, vol.16
, pp. 27-35
-
-
Gil, W.1
-
33
-
-
0030944432
-
Cholinergic stimulation increases thrombin activity and gene expression in cultured mouse muscle
-
Glazner GW, Yadav K, Fitzgerald S, Coven E, Brenneman DE, Nelson PG. 1997. Cholinergic stimulation increases thrombin activity and gene expression in cultured mouse muscle. Brain Res Dev Brain Res 99:148-154.
-
(1997)
Brain Res Dev Brain Res
, vol.99
, pp. 148-154
-
-
Glazner, G.W.1
Yadav, K.2
Fitzgerald, S.3
Coven, E.4
Brenneman, D.E.5
Nelson, P.G.6
-
34
-
-
0022897760
-
A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins
-
Gloor S, Odink K, Guenther J, Nick H, Monard D. 1986. A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins. Cell 47:687-693.
-
(1986)
Cell
, vol.47
, pp. 687-693
-
-
Gloor, S.1
Odink, K.2
Guenther, J.3
Nick, H.4
Monard, D.5
-
35
-
-
0028873060
-
Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: Involvement of tyrosine phosphorylation
-
Grabham P, Cunningham DD. 1995. Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. J Neurochem 64:583-591.
-
(1995)
J Neurochem
, vol.64
, pp. 583-591
-
-
Grabham, P.1
Cunningham, D.D.2
-
36
-
-
0022110035
-
A glia-derived neurite-promoting factor with protease inhibitory activiy
-
Guenther J, Nick H, Monard D. 1985. A glia-derived neurite-promoting factor with protease inhibitory activiy. EMBO J 4:1963-1966.
-
(1985)
EMBO J
, vol.4
, pp. 1963-1966
-
-
Guenther, J.1
Nick, H.2
Monard, D.3
-
37
-
-
0011811083
-
Thrombin modulates and reverses neuroblastoma neurite outgrowth
-
Gurwitz D, Cunningham DD. 1988. Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proc Natl Acad Sci U S A 85:3440-3444.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 3440-3444
-
-
Gurwitz, D.1
Cunningham, D.D.2
-
38
-
-
0025189336
-
Neurite outgrowth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition
-
Gurwitz D, Cunningham DD. 1990. Neurite outgrowth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition. J Cell Physiol 142:155-162.
-
(1990)
J Cell Physiol
, vol.142
, pp. 155-162
-
-
Gurwitz, D.1
Cunningham, D.D.2
-
39
-
-
0023149288
-
Degradation of muscle basement membrane zone by locally generated plasmin
-
Hantaï D, Festoff BW. 1987. Degradation of muscle basement membrane zone by locally generated plasmin. Exp Neurol 95:44-55.
-
(1987)
Exp Neurol
, vol.95
, pp. 44-55
-
-
Hantaï, D.1
Festoff, B.W.2
-
40
-
-
0024269638
-
Serine proteases and serpins: Their possible roles in the motor system
-
Hantaï D, Rao JS, Festoff BW. 1988. Serine proteases and serpins: their possible roles in the motor system. Rev Neurol 144:680-687.
-
(1988)
Rev Neurol
, vol.144
, pp. 680-687
-
-
Hantaï, D.1
Rao, J.S.2
Festoff, B.W.3
-
41
-
-
0344605433
-
Decrease in plasminogen activator correlates with synapse elimination during neonatal development of mouse skeletal muscle
-
Hantaï D, Rao JS, Kahler C, Festoff BW. 1989. Decrease in plasminogen activator correlates with synapse elimination during neonatal development of mouse skeletal muscle. Proc Natl Acad Sci USA 86:362-366.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 362-366
-
-
Hantaï, D.1
Rao, J.S.2
Kahler, C.3
Festoff, B.W.4
-
42
-
-
0025261803
-
Rapid neural regulation of muscle urokinase-like plasminogen activator as defined by nerve crush
-
Hantaï D, Rao JS, Festoff BW. 1990. Rapid neural regulation of muscle urokinase-like plasminogen activator as defined by nerve crush. Proc Natl Acad Sci USA 87:2926-2930.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 2926-2930
-
-
Hantaï, D.1
Rao, J.S.2
Festoff, B.W.3
-
43
-
-
0028685537
-
Serine proteases and their inhibitors: Their role in the differentiation in neuromuscular system
-
Hantai D, Akaaboune M, Verdiere-Sahuque M, Lachkar S, Festoff BW. 1994. Serine proteases and their inhibitors: their role in the differentiation in neuromuscular system. C R Seances Soc Biol Fil 188:541-552.
-
(1994)
C R Seances Soc Biol Fil
, vol.188
, pp. 541-552
-
-
Hantai, D.1
Akaaboune, M.2
Verdiere-Sahuque, M.3
Lachkar, S.4
Festoff, B.W.5
-
44
-
-
0042427857
-
Thrombin-induced apoptosis in motor neurons implicates specific MAP kinase signaling events and redistribution of gp130 in neurites
-
in press
-
Haynes LW, Heywood D, Mellor AH, Citron BA, Festoff BW. 2003. Thrombin-induced apoptosis in motor neurons implicates specific MAP kinase signaling events and redistribution of gp130 in neurites. J Neurobiol (in press).
-
(2003)
J Neurobiol
-
-
Haynes, L.W.1
Heywood, D.2
Mellor, A.H.3
Citron, B.A.4
Festoff, B.W.5
-
45
-
-
0001761205
-
Thrombin induces apoptosis in primary motoneurons in vitro: Localization of PAR-1, Rho-A and MAP kinase activation
-
February
-
Heywood D, Rawle H, Desoutter A, Citron BA, Festoff BW, Haynes LW. 1999. Thrombin induces apoptosis in primary motoneurons in vitro: localization of PAR-1, Rho-A and MAP kinase activation. Br Neurosci Assoc Abstr, February.
-
(1999)
Br Neurosci Assoc Abstr
-
-
Heywood, D.1
Rawle, H.2
Desoutter, A.3
Citron, B.A.4
Festoff, B.W.5
Haynes, L.W.6
-
46
-
-
0033168827
-
Protease-activated receptors: PAR4 and counting: How long is the course?
-
Hollenberg MD. 1999. Protease-activated receptors: PAR4 and counting: how long is the course? Trends Pharmacol Sci 20:271-273.
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 271-273
-
-
Hollenberg, M.D.1
-
47
-
-
0026748742
-
Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers
-
Jalink K, Moolenaar WH. 1992. Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers. J Cell Biol 118:411-419.
-
(1992)
J Cell Biol
, vol.118
, pp. 411-419
-
-
Jalink, K.1
Moolenaar, W.H.2
-
48
-
-
0028021308
-
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein rho
-
Jalink K, van Corren EJ, Hengeveld T, Morii N, Narumiya S, Moolenaar WH. 1994. Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein rho. J Cell Biol 126:801-810.
-
(1994)
J Cell Biol
, vol.126
, pp. 801-810
-
-
Jalink, K.1
Van Corren, E.J.2
Hengeveld, T.3
Morii, N.4
Narumiya, S.5
Moolenaar, W.H.6
-
49
-
-
0032911415
-
Evaluation of proteinase-activated receptor-1 (PAR1 ) agonists and antagonists using a cultured cell receptor desensitization assay: Activation of PAR2 by PAR1-targeted ligands
-
Kawabata A, Saifeddine M, Al-Ani B, Leblond L, Hollenberg MD. 1999. Evaluation of proteinase-activated receptor-1 (PAR1 ) agonists and antagonists using a cultured cell receptor desensitization assay: activation of PAR2 by PAR1-targeted ligands. J Pharmacol Exp Ther 288:358-370.
-
(1999)
J Pharmacol Exp Ther
, vol.288
, pp. 358-370
-
-
Kawabata, A.1
Saifeddine, M.2
Al-Ani, B.3
Leblond, L.4
Hollenberg, M.D.5
-
50
-
-
0032496148
-
Transcriptional regulation of the prothrombin gene in muscle
-
Kim S, Nelson PG. 1998. Transcriptional regulation of the prothrombin gene in muscle. J Biol Chem 273:11923-11929.
-
(1998)
J Biol Chem
, vol.273
, pp. 11923-11929
-
-
Kim, S.1
Nelson, P.G.2
-
51
-
-
0032146182
-
Regulation of prothrombin, thrombin receptor, and protease nexin-1 expression during development and after denervation in muscle
-
Kim S, Buonanno A, Nelson PG. 1998. Regulation of prothrombin, thrombin receptor, and protease nexin-1 expression during development and after denervation in muscle. J Neurosci Res 53:304-311.
-
(1998)
J Neurosci Res
, vol.53
, pp. 304-311
-
-
Kim, S.1
Buonanno, A.2
Nelson, P.G.3
-
52
-
-
0035866068
-
Pertussis toxin-sensitive G-protein and protein kinase C activity are involved in normal synapse elimination in the neonatal rat muscle
-
Lanuza MA, Garcia N, Santafe M, Nelson PG, Fenoll-Brunet MR, Tomas J. 2001. Pertussis toxin-sensitive G-protein and protein kinase C activity are involved in normal synapse elimination in the neonatal rat muscle. J Neurosci Res 63:330-340.
-
(2001)
J Neurosci Res
, vol.63
, pp. 330-340
-
-
Lanuza, M.A.1
Garcia, N.2
Santafe, M.3
Nelson, P.G.4
Fenoll-Brunet, M.R.5
Tomas, J.6
-
53
-
-
0029603565
-
Intracerebral infusion of thrombin as a cause of brain edema
-
Lee KR, Betz AL, Keep RF, Chenevert TL, Kim S, Hoff JT 1995. Intracerebral infusion of thrombin as a cause of brain edema. J Neurosurg 83:1045-1050.
-
(1995)
J Neurosurg
, vol.83
, pp. 1045-1050
-
-
Lee, K.R.1
Betz, A.L.2
Keep, R.F.3
Chenevert, T.L.4
Kim, S.5
Hoff, J.T.6
-
54
-
-
0027948168
-
Proteolytic action of thrombin is required for electrical activity-dependent synapse reduction
-
Liu Y, Fields RD, Festoff BW, Nelson PG. 1994a. Proteolytic action of thrombin is required for electrical activity-dependent synapse reduction. Proc Natl Acad Sci USA 91:10300-10304.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10300-10304
-
-
Liu, Y.1
Fields, R.D.2
Festoff, B.W.3
Nelson, P.G.4
-
55
-
-
0028296632
-
Proteolytic activity, synapse elimination, and the Hebb synapse
-
Liu Y, Fields RD, Fitzgerald S, Festoff BW, Nelson PG. 1994b. Proteolytic activity, synapse elimination, and the Hebb synapse. J Neurobiol 25:325-335.
-
(1994)
J Neurobiol
, vol.25
, pp. 325-335
-
-
Liu, Y.1
Fields, R.D.2
Fitzgerald, S.3
Festoff, B.W.4
Nelson, P.G.5
-
56
-
-
0035019636
-
Proteinase-activated receptors
-
Macfarlane SR, Seatter MJ, Kanke T, Hunter GD, Plevin R. 2001. Proteinase-activated receptors. Pharmacol Rev 53:245-282.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 245-282
-
-
Macfarlane, S.R.1
Seatter, M.J.2
Kanke, T.3
Hunter, G.D.4
Plevin, R.5
-
57
-
-
0034625743
-
The effects of thrombin preconditioning on focal cerebral ischemia in rats
-
Masada T, Yi G, Hua Y, Keep RF. 2000. The effects of thrombin preconditioning on focal cerebral ischemia in rats. Brain Res 867:173-179.
-
(2000)
Brain Res
, vol.867
, pp. 173-179
-
-
Masada, T.1
Yi, G.2
Hua, Y.3
Keep, R.F.4
-
58
-
-
0033822556
-
Thrombin-induced activation of cultured rodent microglia
-
Moller T, Hanisch UK, Ransom BR. 2000. Thrombin-induced activation of cultured rodent microglia. J Neurochem 75:1539-1547.
-
(2000)
J Neurochem
, vol.75
, pp. 1539-1547
-
-
Moller, T.1
Hanisch, U.K.2
Ransom, B.R.3
-
59
-
-
0020689778
-
Inhibition of protease activity can lead to neurite extension in neuroblastoma cells
-
Monard D, Niday E, Limat A, Solomon F. 1983. Inhibition of protease activity can lead to neurite extension in neuroblastoma cells. Progr Brain Res 58:309-364.
-
(1983)
Progr Brain Res
, vol.58
, pp. 309-364
-
-
Monard, D.1
Niday, E.2
Limat, A.3
Solomon, F.4
-
60
-
-
0036699588
-
The coagulopathy in acute head injury: Comparison of cerebral versus peripheral measurements of haemostatic activation markers
-
Murshid WR, Gader AG. 2002. The coagulopathy in acute head injury: comparison of cerebral versus peripheral measurements of haemostatic activation markers. Br J Neurosurg 16:362-369.
-
(2002)
Br J Neurosurg
, vol.16
, pp. 362-369
-
-
Murshid, W.R.1
Gader, A.G.2
-
61
-
-
0034611727
-
PAR3 is a cofactor for PAR4 activation by thrombin
-
Nakanishi-Matsui M, Zheng YW, Sulciner DJ, Weiss EJ, Ludeman MJ, Coughlin SR. 2000. PAR3 is a cofactor for PAR4 activation by thrombin. Nature 404:609-613.
-
(2000)
Nature
, vol.404
, pp. 609-613
-
-
Nakanishi-Matsui, M.1
Zheng, Y.W.2
Sulciner, D.J.3
Weiss, E.J.4
Ludeman, M.J.5
Coughlin, S.R.6
-
62
-
-
0027326873
-
Thrombin may contribute to the pathophysiology of central nervous system injury
-
Nishino A, Suzuki M, Ohtani H, Motohashi O, Umezawa K, Nagura H, Yoshimoto T. 1993. Thrombin may contribute to the pathophysiology of central nervous system injury. J Neurotrauma 10:167-179.
-
(1993)
J Neurotrauma
, vol.10
, pp. 167-179
-
-
Nishino, A.1
Suzuki, M.2
Ohtani, H.3
Motohashi, O.4
Umezawa, K.5
Nagura, H.6
Yoshimoto, T.7
-
63
-
-
0035707639
-
Regulation of inflammatory responses by natural anticoagulants
-
Okajima K. 2001. Regulation of inflammatory responses by natural anticoagulants. Immunol Rev 184:258-274.
-
(2001)
Immunol Rev
, vol.184
, pp. 258-274
-
-
Okajima, K.1
-
64
-
-
0032146770
-
Thrombin-induced reversal of astrocyte stellation is mediated by activation of protein kinase C beta-1
-
Pindon A, Festoff BW, Hantai D. 1998. Thrombin-induced reversal of astrocyte stellation is mediated by activation of protein kinase C beta-1. Eur J Biochem 255:766-774.
-
(1998)
Eur J Biochem
, vol.255
, pp. 766-774
-
-
Pindon, A.1
Festoff, B.W.2
Hantai, D.3
-
65
-
-
0025784847
-
cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization
-
Rasmussen UB, Vouret-Craviari V, Jallat S, Schlesinger Y, Pages G, Pavirani A, Lecocq JP, Pouyssegur J, Van Obberghen-Schilling E. 1991. cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization. FEBS Lett 288:123-128.
-
(1991)
FEBS Lett
, vol.288
, pp. 123-128
-
-
Rasmussen, U.B.1
Vouret-Craviari, V.2
Jallat, S.3
Schlesinger, Y.4
Pages, G.5
Pavirani, A.6
Lecocq, J.P.7
Pouyssegur, J.8
Van Obberghen-Schilling, E.9
-
66
-
-
0034730753
-
Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B
-
Ryu J, Pyo H, Jou I, Joe E. 2000. Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B. J Biol Chem 275:29955-29959.
-
(2000)
J Biol Chem
, vol.275
, pp. 29955-29959
-
-
Ryu, J.1
Pyo, H.2
Jou, I.3
Joe, E.4
-
67
-
-
0031823351
-
Quantitative reverse transcriptase PCR to gauge increased protease-activated receptor 1 (PAR-1] mRNA copy numbers in the Wobbler mutant mouse
-
Salcedo RM, Festoff BW, Citron BA. 1998. Quantitative reverse transcriptase PCR to gauge increased protease-activated receptor 1 (PAR-1] mRNA copy numbers in the Wobbler mutant mouse. J Mol Neurosci 10:113-119.
-
(1998)
J Mol Neurosci
, vol.10
, pp. 113-119
-
-
Salcedo, R.M.1
Festoff, B.W.2
Citron, B.A.3
-
68
-
-
0030730261
-
Nervous system-specific expression of a novel serine protease: Regulation in the adult rat spinal cord by excitotoxic injury
-
Scarisbrick IA, Towner MD, Isackson PJ. 1997. Nervous system-specific expression of a novel serine protease: regulation in the adult rat spinal cord by excitotoxic injury. J Neurosci 17:8156-8168.
-
(1997)
J Neurosci
, vol.17
, pp. 8156-8168
-
-
Scarisbrick, I.A.1
Towner, M.D.2
Isackson, P.J.3
-
69
-
-
0031813736
-
Thrombin is an extracellular signal that activates intracellular death protease pathways inducing apoptosis in model motor neurons
-
Smirnova IV, Zhang SX, Citron BA, Arnold PM, Festoff BW. 1998a. Thrombin is an extracellular signal that activates intracellular death protease pathways inducing apoptosis in model motor neurons. J Neurobiol 36:64-80.
-
(1998)
J Neurobiol
, vol.36
, pp. 64-80
-
-
Smirnova, I.V.1
Zhang, S.X.2
Citron, B.A.3
Arnold, P.M.4
Festoff, B.W.5
-
70
-
-
0031814260
-
Calcium mobilization and protease-activated receptor cleavage after thrombin stimulation in motor neurons
-
Smirnova IV, Vamos S, Wiegmann T, Citron BA, Arnold PM, Festoff BW. 1998b. Calcium mobilization and protease-activated receptor cleavage after thrombin stimulation in motor neurons. J Mol Neurosci 10:31-44.
-
(1998)
J Mol Neurosci
, vol.10
, pp. 31-44
-
-
Smirnova, I.V.1
Vamos, S.2
Wiegmann, T.3
Citron, B.A.4
Arnold, P.M.5
Festoff, B.W.6
-
71
-
-
0034958701
-
Neuroprotective signal transduction in model motor neurons exposed to thrombin: G-protein modulation effects on neurite outgrowth, Ca[2+] mobilization, and apoptosis
-
Smirnova IV, Citron BA, Arnold PM, Festoff BW. 2001. Neuroprotective signal transduction in model motor neurons exposed to thrombin: G-protein modulation effects on neurite outgrowth, Ca[2+] mobilization, and apoptosis. J Neurobiol 48:87-100.
-
(2001)
J Neurobiol
, vol.48
, pp. 87-100
-
-
Smirnova, I.V.1
Citron, B.A.2
Arnold, P.M.3
Festoff, B.W.4
-
72
-
-
0028239957
-
Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development
-
Soifer SJ, Peters KG, O'Keefe J, Coughlin SR. 1994. Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development. Am J Pathol 144:60-69.
-
(1994)
Am J Pathol
, vol.144
, pp. 60-69
-
-
Soifer, S.J.1
Peters, K.G.2
O'Keefe, J.3
Coughlin, S.R.4
-
73
-
-
0023646684
-
cDNA sequence coding for a rat glia-derived nexin and its homology to members of the serpin superfamily
-
Sommer J, Gloor SM, Rovelli GF, Hofsteenge J, Nick H, Meier R, Monard D. 1987. cDNA sequence coding for a rat glia-derived nexin and its homology to members of the serpin superfamily. Biochemistry 26:6407-6410.
-
(1987)
Biochemistry
, vol.26
, pp. 6407-6410
-
-
Sommer, J.1
Gloor, S.M.2
Rovelli, G.F.3
Hofsteenge, J.4
Nick, H.5
Meier, R.6
Monard, D.7
-
74
-
-
0034053127
-
The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations
-
Striggow F, Riek M, Breder J, Henrich-Noack P, Reymann KG, Reiser G. 2000. The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations. Proc Natl Acad Sci U S A 97:2264-2269.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2264-2269
-
-
Striggow, F.1
Riek, M.2
Breder, J.3
Henrich-Noack, P.4
Reymann, K.G.5
Reiser, G.6
-
75
-
-
0035235956
-
Thrombin as a regulator of inflammation and reparative processes in tissues
-
Strukova SM. 2001. Thrombin as a regulator of inflammation and reparative processes in tissues. Biochemistry (Mosc) 66:8-18.
-
(2001)
Biochemistry (Mosc)
, vol.66
, pp. 8-18
-
-
Strukova, S.M.1
-
76
-
-
0036326804
-
Participation of protease-activated receptor-1 in thrombin-induced microglial activation
-
Suo Z, Wu M, Ameenuddin S, Anderson HE, Zoloty JE, Citron BA, Andrade-Gordon P, Festoff BW. 2002. Participation of protease-activated receptor-1 in thrombin-induced microglial activation. J Neurochem 80:655-666.
-
(2002)
J Neurochem
, vol.80
, pp. 655-666
-
-
Suo, Z.1
Wu, M.2
Ameenuddin, S.3
Anderson, H.E.4
Zoloty, J.E.5
Citron, B.A.6
Andrade-Gordon, P.7
Festoff, B.W.8
-
77
-
-
0042904881
-
Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation
-
in press
-
Suo Z, Wu M, Citron BA, Gao C-H, Festoff BW. 2003a. Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation. J Biol Chem (in press).
-
(2003)
J Biol Chem
-
-
Suo, Z.1
Wu, M.2
Citron, B.A.3
Gao, C.-H.4
Festoff, B.W.5
-
78
-
-
0042928557
-
Rapid induction of neurofibrillary tangle formation in HT22 hippocampal neurons by thrombin
-
in press
-
Suo Z, Wu, M, Zoloty JE, Citron BA, Palazzo RE, Festoff BW. 2003b. Rapid induction of neurofibrillary tangle formation in HT22 hippocampal neurons by thrombin. J Biol Chem (in press).
-
(2003)
J Biol Chem
-
-
Suo, Z.1
Wu, M.2
Zoloty, J.E.3
Citron, B.A.4
Palazzo, R.E.5
Festoff, B.W.6
-
79
-
-
17344365478
-
Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation
-
Turgeon VL, Lloyd ED, Wang S, Festoff BW, Houenou LJ. 1998. Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation. J Neurosci 18:6882-6891.
-
(1998)
J Neurosci
, vol.18
, pp. 6882-6891
-
-
Turgeon, V.L.1
Lloyd, E.D.2
Wang, S.3
Festoff, B.W.4
Houenou, L.J.5
-
80
-
-
0031539290
-
Characteristics of thrombin-induced calcium signals in rat astrocytes
-
Ubl JJ, Reiser G. 1997. Characteristics of thrombin-induced calcium signals in rat astrocytes. Glia 21:361-369.
-
(1997)
Glia
, vol.21
, pp. 361-369
-
-
Ubl, J.J.1
Reiser, G.2
-
81
-
-
0034213673
-
Desensitisation of protease-activated receptor-1 (PAR-1] in rat astrocytes: Evidence for a novel mechanism for terminating Ca2+ signalling evoked by the tethered ligand
-
Ubl JJ, Sergeeva M, Reiser G. 2000. Desensitisation of protease-activated receptor-1 (PAR-1] in rat astrocytes: evidence for a novel mechanism for terminating Ca2+ signalling evoked by the tethered ligand. J Physiol (Lond.) 525:319-330.
-
(2000)
J Physiol (Lond.)
, vol.525
, pp. 319-330
-
-
Ubl, J.J.1
Sergeeva, M.2
Reiser, G.3
-
82
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu TK, Hung DT, Wheaton VI, Coughlin SR. 1991. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64:1057-1068.
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
Hung, D.T.2
Wheaton, V.I.3
Coughlin, S.R.4
-
83
-
-
0037332454
-
The role of the Ca2+-sensitive tyrosine kinase Pyk2 and Src in thrombin signalling in rat astrocytes
-
Wang H, Reiser G. 2003. The role of the Ca2+-sensitive tyrosine kinase Pyk2 and Src in thrombin signalling in rat astrocytes. J Neurochem 84:1349-1357.
-
(2003)
J Neurochem
, vol.84
, pp. 1349-1357
-
-
Wang, H.1
Reiser, G.2
-
84
-
-
0036006726
-
Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling
-
Wang H, Ubl JJ, Beiser G. 2002. Four subtypes of protease-activated receptors, co-expressed in rat astrocytes, evoke different physiological signaling. Glia 37:53-63.
-
(2002)
Glia
, vol.37
, pp. 53-63
-
-
Wang, H.1
Ubl, J.J.2
Beiser, G.3
-
85
-
-
0028914068
-
Cellular localization of thrombin receptor mRNA in rat brain: Expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA
-
Weinstein JB, Gold SJ, Cunningham DD, Gall CM. 1995. Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J Neurosci 15:2906-2919.
-
(1995)
J Neurosci
, vol.15
, pp. 2906-2919
-
-
Weinstein, J.B.1
Gold, S.J.2
Cunningham, D.D.3
Gall, C.M.4
-
86
-
-
0034570591
-
Thrombin preconditioning, heat shock proteins and thrombin-induced brain edema
-
Xi G, Keep RF, Hua Y, Hoff JT. 2000. Thrombin preconditioning, heat shock proteins and thrombin-induced brain edema. Acta Neurochir Suppl 76:511-515.
-
(2000)
Acta Neurochir Suppl
, vol.76
, pp. 511-515
-
-
Xi, G.1
Keep, R.F.2
Hua, Y.3
Hoff, J.T.4
-
87
-
-
0033000918
-
Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning
-
Xi G, Keep RF, Hua Y, Xiang J, Hoff JT. 1999. Attenuation of thrombin-induced brain edema by cerebral thrombin preconditioning. Stroke 30:1247-1255.
-
(1999)
Stroke
, vol.30
, pp. 1247-1255
-
-
Xi, G.1
Keep, R.F.2
Hua, Y.3
Xiang, J.4
Hoff, J.T.5
-
88
-
-
0037265689
-
The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: Deleterious or protective?
-
Xi G, Reiser G, Keep RF. 2003. The role of thrombin and thrombin receptors in ischemic, hemorrhagic and traumatic brain injury: deleterious or protective? J Neurochem 84:3-9.
-
(2003)
J Neurochem
, vol.84
, pp. 3-9
-
-
Xi, G.1
Reiser, G.2
Keep, R.F.3
-
89
-
-
0032499696
-
Cloning and characterization of human protease-activated receptor 4
-
Xu WF, Andersen H, Whitmore TE, Presnell SR, Yee DP, Ching A, Gilbert T, Davie EW, Foster DC. 1998. Cloning and characterization of human protease-activated receptor 4. Proc Natl Acad Sci USA 95:6642-6646.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6642-6646
-
-
Xu, W.F.1
Andersen, H.2
Whitmore, T.E.3
Presnell, S.R.4
Yee, D.P.5
Ching, A.6
Gilbert, T.7
Davie, E.W.8
Foster, D.C.9
-
90
-
-
0034827647
-
Acute tissue damage after injections of thrombin and plasmin into rat striatum
-
Xue M, Del Bigio MR. 2001. Acute tissue damage after injections of thrombin and plasmin into rat striatum. Stroke 32:2164-2169.
-
(2001)
Stroke
, vol.32
, pp. 2164-2169
-
-
Xue, M.1
Del Bigio, M.R.2
-
91
-
-
0031864024
-
Apoptosis in cellular compartments of rat spinal cord after severe conlusion injury
-
Yong C, Arnold PM, Zoubine MN, Citron BA, Watanabe I, Berman NE, Festoff BW. 1998. Apoptosis in cellular compartments of rat spinal cord after severe conlusion injury. J Neurotrauma 15:459-472.
-
(1998)
J Neurotrauma
, vol.15
, pp. 459-472
-
-
Yong, C.1
Arnold, P.M.2
Zoubine, M.N.3
Citron, B.A.4
Watanabe, I.5
Berman, N.E.6
Festoff, B.W.7
-
92
-
-
0039534893
-
A molecular mechanism for synapse elimination: Novel inhibition of locally generated thrombin delays synapse loss in neonatal mouse muscle
-
Zoubine MN, Ma JY, Smirnova IV, Citron BA, Festoff BW. 1996. A molecular mechanism for synapse elimination: novel inhibition of locally generated thrombin delays synapse loss in neonatal mouse muscle. Dev Biol 179:447-457.
-
(1996)
Dev Biol
, vol.179
, pp. 447-457
-
-
Zoubine, M.N.1
Ma, J.Y.2
Smirnova, I.V.3
Citron, B.A.4
Festoff, B.W.5
|