Persistent protease-activated receptor 4 signaling mediates thrombin-induced microglial activation

Journal of Biological Chemistry

Volumn 278, Issue 33, 2003, Pages 31177-31183

  Suo, Zhiming ^a,b   Wu, Min ^a   Citron, Bruce A ^a,b   Gao, Chenhua ^a   Festoff, Barry W ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BRAIN; CELL CULTURE; CYTOLOGY; NEUROLOGY; TUMORS;

MICROGLIAL CELLS;

PROTEINS;

ANTISENSE OLIGONUCLEOTIDE; CALCIUM ION; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE; PROTEIN P42; PROTEIN P44; PROTEINASE ACTIVATED RECEPTOR 4; SERINE PROTEINASE; THROMBIN; THROMBIN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MEDIATOR RELEASE; MICROGLIA; MOUSE; NERVE DEGENERATION; NERVOUS SYSTEM INJURY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CELLS, CULTURED; DOWN-REGULATION; HEMOSTATICS; MAP KINASE SIGNALING SYSTEM; MICE; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHORYLATION; RECEPTORS, THROMBIN; THROMBIN; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; MURINAE;

EID: 0042904881     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302137200     Document Type: Article

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