Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers

Bioorganic and Medicinal Chemistry

Volumn 10, Issue 8, 2002, Pages 2663-2669

  Caliendo, Giuseppe ^a   Perissutti, Elisa ^a   Santagada, Vincenzo ^a   Fiorino, Ferdinando ^a   Severino, Beatrice ^a   Di Villa Bianca, Roberta d'Emmanuele ^a   Lippolis, Laura ^b   Pinto, Aldo ^b   Sorrentino, Raffaella ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 (3,4 DIHYDRO 3 OXO 2H 1,4 BENZOXAZIN 4 YL)ETHYLPROPIONATE; 3 [3,4 DIHYDRO 3 OXO 6 (DELTA 2 THIAZOLIN 2 YL) 2H 1,4 BENZOXAZIN 4 YL]ETHYLPROPIONATE; 4 (3,4 DIHYDRO 3 OXO 2H 1,4 BENZOXAZIN 4 YL)ETHYLBUTYRATE; 4 [3,4 DIHYDRO 3 OXO 6 (DELTA 2 THIAZOLIN 2 YL) 2H 1,4 BENZOXAZIN 4 YL]ETHYLBUTYRATE; CROMAKALIM; OXAZINE DERIVATIVE; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG SYNTHESIS; MALE; NONHUMAN; RAT; VASODILATATION; ANIMAL; AORTA; CHANNEL GATING; DOSE RESPONSE; DRUG EFFECT; STRUCTURE ACTIVITY RELATION; SYNTHESIS; WISTAR RAT;

ANIMALS; AORTA; CROMAKALIM; DOSE-RESPONSE RELATIONSHIP, DRUG; ION CHANNEL GATING; MALE; OXAZINES; POTASSIUM CHANNELS; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP; VASODILATION;

EID: 0036280404     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00091-3     Document Type: Article

References (14)