Synthesis and biological activity of novel 1,3-benzoxazine derivatives as K+ channel openers

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 4, 1996, Pages 734-745

  Yamamoto, Satoshi ^a   Hashiguchi, Shohei ^a   Miki, Shokyo ^a   Igata, Yumiko ^a   Watanabe, Toshifumi ^a   Shiraishi, Mitsuru ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

4 (2 pyridyl) 2H 1,3 benzoxazine; hypotensive effect; K+ channel opener

Indexed keywords

1,3 BENZOXAZINE DERIVATIVE; 2 (6 BROMO 7 CHLORO 2,2 DIMETHYL 2H 1,3 BENZOXAZIN 4 YL)PYRIDINE 1 OXIDE; APRIKALIM; BENZOXAZINE DERIVATIVE; CROMAKALIM; DIAZOXIDE; MINOXIDIL SULFATE; NICORANDIL; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL AFFECTING AGENT; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; AORTA; ARTICLE; BLOOD PRESSURE MEASUREMENT; HYPERTENSION; HYPOTENSION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SMOOTH MUSCLE RELAXATION; SPONTANEOUSLY HYPERTENSIVE RAT; VASODILATATION;

EID: 0029919047     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.734     Document Type: Article

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