Psychophysical evidence for rod vulnerability in age-related macular degeneration

Investigative Ophthalmology and Visual Science

Volumn 41, Issue 1, 2000, Pages 267-273

  Owsley, Cynthia ^a   Jackson, Gregory R ^a   Cideciyan, Artur V ^b   Huang, Yijun ^b   Fine, Stuart L ^b   Ho, Allen C ^b   Maguire, Maureen G ^b   Lolley, Virginia ^a   Jacobson, Samuel G ^b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DARK ADAPTATION; FEMALE; HUMAN; LIGHT ADAPTATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PSYCHOPHYSICS; RETINA MACULA AGE RELATED DEGENERATION; RETINA ROD;

AGED; AGED, 80 AND OVER; DARK ADAPTATION; FEMALE; HUMANS; MACULAR DEGENERATION; MALE; MIDDLE AGED; PERIMETRY; PSYCHOPHYSICS; RODS (RETINA); VISUAL FIELDS;

EID: 0033989336     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (67)

1. Bressler NM, Bressler SB, Fine SL. Age-related macular degeneration. Surv Ophthalmol. 1988;32:375-413.
2. Bird AC, Age-related macular disease Br J Ophthalmol. 1996;80: 2-3.
3. Zarbin MA. Age-related maculur degeneration: review of pathogenesis. Eur J Ophthalmol. 1998;8:199-206.
4. Curcio CA, Medeiros NE, Millican CL. Photoreceptor loss in age-related macular degeneration. Invest Ophthalmol Vis Sci. 1996;37: 1236-1249.
5. Sunness JS, Massof RW, Johnson MA, Finkelstein D, Fine SL. Peripheral retinal function in age-related macular degeneration. Arch Ophthalmol. 1985;103:811-816.
6. Eisner A, Fleming SA, Klein ML, Mauldin WM. Sensitivities in older eyes with good acuity: eyes whose fellow eye has exudative AMD. invest Ophthalmol Vis Sci. 1987;28:1832-1837.
7. Sunness JS, Johnson MA, Massof RW, Marcus S. Retinal sensitivity over drusen and nondrusen areas. A study using fundus perimetry. Arch Ophthalmol. 1988;106:1081-1084.
8. Sunness JS, Massof RW, Johnson MA, Bressler NM, Bressler SB, Fine SL. Diminished foveal sensitivity may predict the development of advanced age-related macular degeneration. Ophthalmology 1989; 96:375-381.
9. Massof RW, Choy D. Sunness JS, Johnson MA, Rubin GS, Fine SL. Foveal threshold elevations associated with age-related drusen. Clin Vision Sci. 1989;4:221-227.
10. Eisner A, Stoumbos VD, Klein ML, Fleming SA. Relations between fundus appearance and function: eyes whose fellow eye has exudative age-related macular degeneration. Invest Ophthalmol Vis Sci. 1991;32:8-20.
11. Eisner A. Klein ML, Zilis JD, Watkins MD. Visual function and the subsequent development of exudative age-related macular degeneration, Invest Ophthalmol Vis Sci. 1992;33:3091-3102.
12. Chen JC, Fitzke FW, Pauleikhoff D, Bird AC. Functional loss in age-related Bruch's membrane change with choroidal perfusion defect. Invest Ophthalmol Vis Sci. 1992;33:334-340.
13. Steinmetz RL, Haimovici R, Jubb C, Fitzke FW, Bird AC. Symptomatic abnormalities of dark adaptation in patients with age-related Bruch's membrane change. Br J Ophthalmol. 1993;77:549-554.
14. Sunness JS, Rubin GS, Applegate CA, et al. Visual function abnormalities and prognosis in eyes with age-related geographic atrophy of the macula and good acuity. Ophthalmology 1997;104:1677-1691.
15. Guymer RH, Gross-Jendroska M, Owens SL, Bid AC, Fitzke F. Laser treatment in subjects with high risk clinical features of age-related macular degeneration. Arch Ophthalmol. 1997;115:595-603.
16. Bird AC, Bressler NM, Bressler SB, et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration: the international ARM epidemiological study group. Surv Ophthalmol. 1995;39:367-374.
17. Klein R, Davis MD, Magli YL, Segal P, Klein BEK, Hubbard L. The Wisconsin age-related maculopathy grading system. Ophthalmol. 1991;98:1128-1134.
18. Chuang EL, Bird AC. The pathogenesis of tears of the retinal pigment epithelium. Am J Ophthalmol. 1988;105:285-290.
19. Maguire MG. Natural history. In: Berger JW, Fine SL, Maguire MG, eds. Age-Related Macular Degeneration. St. Louis: Mosby Year-Book; 1999:17-30.
20. Jacobson SG, Voigt WJ, Parel JM, et al. Automated light-and dark-adapted perimetry for evaluating retinitis pigmentosa. Ophthalmology. 1986;93:1604-1611.
21. Jacobson SG. Apathy PP, Parel JM. Rod and cone perimetry: computerized testing and analysis. In: Heckenlively J, Arden G, eds. Handbook of Clinical Vision Testing. St. Louis: Mosby Year-Book; 1991:475-482.
22. Jackson GR, Owsley C, Cordle EP, Finley CD Aging and scotopic sensitivity. Vision Res. 1998;38:3655-3662.
23. Massof RW, Finkelstein D. Two forms of autosomal dominant primary retinitis pigmentosa. Doc Ophthalmol. 1981;51:289-346.
24. Gunkel RD, Gouras P. Changes in scotopic visibility thresholds with age. Arch Ophthalmol. 1963;69:4-9.
25. Johnson CA, Adams AJ, Lewis RA. Evidence for a neural basis of age-related visual field loss in normal observers. Invest Ophthalmol Vis Sci. 1989;30:2056-2064.
26. van Norren D, Vos JJ. Spectral transmission of the human ocular media. Vision Res. 1974;14:1237-1244.
27. Sample PA, Esterson FD, Weinreb RN, Boynton RM. The aging lens: in vivo assessment of light absorption in 84 human eyes. Invest Ophthalmol Vis Sci. 1988;29:1306-1311.
28. Pulos E. Changes in rod sensitivity through adulthood. Invest Ophthalmol Vis Sci. 1989;30:1738-1742.
29. Lutze M, Bresnick GH. Lens-corrected visual field sensitivity and diabetes. Invest Ophthalmol Vis Sci. 1994;35:649-655.
30. Sturr JF, Zhang L, Taub HA, Hannon DJ, Jackowski MM. Psychophysical evidence for losses in rod sensitivity in the aging visual system. Vision Res. 1997;37:475-481.
31. Dartnall HJA, Bowmaker JK, Mollon JD. Human visual pigments. Proc R Soc Lond B. 1983;220:115-130.
32. Pokorny J, Smith VC, Lutze M. Aging of the human lens. Appl Optics. 1987;26:1437-1440.
33. van den Berg TJ, Felius J. Relationship between spectral transmittance and slit lamp color of human lenses. Invest Ophthalmol Vis Sci. 1995;36:322-329.
34. Mainster MA. The spectra, classification, and rationale of ultraviolet-protective intraocular lenses. Am J Ophthalmol. 1986;102:727-732.
35. Lutze M, Bresnick GH. Lenses of diabetic patients "yellow" at an accelerated rate similar to older normals, Invest Ophthalmol Vis Sci. 1991;32:194-199.
36. Greenstein V. Hood DC, Carr RE. Foveal sensitivity changes in retinitis pigmentosa. Appl Optics. 1987;26:1385-1389.
37. Yeh T, Smith VC, Pokorny J. The effect of background luminance on cone sensitivity functions. Invest Ophthalmol Vis Sci. 1989;30: 2077-2086.
38. Alexander KR, Derlacki DJ, Fishman GA, Peachey NS. Acuityluminance and foveal increment threshold functions in retinitis pigmentosa. Invest Ophthalmol Vis Sci. 1989;32:1446-1454.
39. Seiple WH, Holopigian K, Greenstein VC, Hood DC. Sites of cone system sensitivity loss in retinitis pigmentosa. Invest Ophthalmol Vis Sci. 1993;34:2638-2645.
40. Applegate RA, Adams AJ, Cavender JC, Zisman F. Early color vision changes in age-related maculopathy. Appl Optics. 1987;26:1458-1462.
41. Midena E, Angeli CD, Blarzino MC, Valenti M, Segato T. Macular function impairment in eyes with early age-related niacular degeneration. Invest Ophthalmol Vis Sci. 1997;38:469-477.
42. Smith VC, Pokorny J, Diddie KR. Color matching and the Stiles-Crawford effect in observers with early age-related macular changes. J Opt Soc. Am. 1988;5:2113-2121.
43. Mayer MJ, Ward B, Klein R, Talcott JB, Dougherty RF, Glues A. Flicker sensitivity and fundus appearance in pre-exudative age-related maculopathy. Invest Ophthalmol Vis Sci. 1994;35:1138-1149.
44. Owsley C, Sloane ME, skalka HW, Jackson CA. A comparison of the Regan low-contrast letter charts and contrast sensitivity testing in older patients. Clin Vision Sci. 1990;5:325-334.
45. Sjostrand J, Frisen L. Contrast sensitivity in macular disease: A preliminary report. Acta Ophthalmol (Copehb). 1977;55:507-514.
46. Fish GE, Birch DG, Fuller DG, Straach R. A comparison of visual function tests in eyes with maculopathy. Ophthalmology. 1986; 93:1177-1182.
47. Sandberg MA, Miller S, Gaudio AR. Foveal cone ERGs in fellow eyes of patients with unilateral neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 1993;34:3477-3480.
48. Brown B. Adams AJ. Coletta NJ, Haegerstrom-Portnoy G. Dark adaptation in age-related maculopathy. Ophthalmic Physiol Opt. 1986;6:81-84.
49. Brown B, Tobin C, Roche N, Wolanowski A. Cone adaptation in age-related maculopathy. Am J Optom Physiol Opt. 1986;63:450-454.
50. Holopigian K, Seiple W, Greenstein V, Kim D, Carr RE. Relative effects of aging and age-related macular degeneration on peripheral visual function. Optom Vis Sci. 1997;74:152-159.
51. Weiter JJ, Delori F, Dorey C.K. Central sparing in annular macular degeneration. Am J Ophthalmol. 1988;106:286-292.
52. Sarks JP, Sarks SH, Killingsworth MC. Evolution of geographic atrophy of the retinal pigment epithelium. Eye. 1988;2:552-577.
53. Hartnett ME, Elsner AE. Characteristics of exudative age-related macular degeneration determined in vivo with confocal and indirect infrared imaging. Ophthalmology. 1996;103:58-71.
54. Lois N, Halfyard AS, Bunce C, Bird AC, Fitzke FW. Reproducibility of fundus autotluorescence measurements obtained using a confocal scanning laser ophthalmoscope. Br J Ophthalmol. 1999;83: 276-279.
55. Jackson GR, Edwards DJ, McGwin G Jr, Owsley C, Changes in dark adaptation in early AMD [ARVO Abstract]. Invest Ophthalmol Vis Sci 1999;40(4):S739. Abstract nr 3911.
56. Jackson GR, Owsley C, McGwin G Jr. Aging and dark adaptation Vision Res. 1999;39:3975-3982.
57. Jacobson SG, Cideciyan AV, Regunath G, et al. Night blindness in Sorsby's fundus dystrophy reversed by vitamin A. Nat Genet. 1995;11:27-32.
58. Kuntz CA, Jacobson SG, Cideciyan AV, et al. Sub-retinal pigment epithelial deposits in a dominant late-onset retinal degeneration. Invest Ophthalmol Vis Sci. 1996;38:1772-1782.
59. Cideciyan AV, Pugh EN Jr, Lamb TD, Huang Y, Jacobson SG. Rod plateau during dark adaptation in Sorsby's fundus dystrophy and vitamin A deficiency. Invest Ophthalmol Vis Sci, 1997;38:1786-1794.
60. Strahlman ER, Fine SL, Hillis A. The second eye of patients with senile macular degeneration. Arch Ophthalmol. 1983;101:1191-1193.
61. Roy M, Kaiser-Kupfer M. Second eye involvement in age-related macular degeneration: a four-year prospective study. Eye. 1990;4: 813-818.
62. Macular Photocoagulation Study Group. Five-year follow-up of fellow eyes of patients with age-related macular degeneration and unilateral extrafoveal choroidal neovascularixation Arch Ophthalmol. 1993;111:1189-1199.
63. Chen J, Maguire MG, Fine SL, Arnold MB. Night vision symptoms in patients with age-related macular degeneration and age-matched controls [ARVO Abstract]. Invest Ophthalmol Vis. 1998;39(4): S602. Abstract nr 2788.
64. Nichols BE, Sheffield VC, Vandenburgh K, Drack AV, Kimura AE, Stone EM. Butterfly-shaped pigment dystrophy of the fovea caused by a point mutation in codon 167 of the RDS gene. Nat Genet. 1993;3:202-207.
65. Petrukhin K, Koisti MJ, Bakall B, et al. Identification of the gene responsible for Best macular dystrophy. Nat Genet. 1998;19:241-247.
66. Allikmets R, Singh N, Sun H, et al. A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy. Nat Genet. 1997;15:236-246.
67. Stone EM, Lotery AJ, Munier FL, et al. A single EFEMP 1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy. Nat Genet. 1999;22:199-202.