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Volumn 15, Issue 14, 2003, Pages 1184-1187

Carbon nanotube-based biosensor

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOSENSORS; ELECTRODES; LIGHT EMISSION; LUMINESCENT DEVICES; PHOTONS; SYNTHESIS (CHEMICAL);

EID: 0041659083     PISSN: 09359648     EISSN: None     Source Type: Journal    
DOI: 10.1002/adma.200304259     Document Type: Article
Times cited : (158)

References (42)
  • 1
    • 0042339535 scopus 로고
    • US Patent 4 663 230
    • H. G. Tennant, US Patent 4 663 230, 1987.
    • (1987)
    • Tennant, H.G.1
  • 2
    • 0342819025 scopus 로고
    • S. Iijima, Nature 1991, 354, 56.
    • (1991) Nature , vol.354 , pp. 56
    • Iijima, S.1
  • 31
    • 0042339536 scopus 로고    scopus 로고
    • note
    • -2.
  • 32
    • 0041838385 scopus 로고    scopus 로고
    • note
    • Nanotubes provided by Hyperion Catalysis Incorporated (Hyperion Fibrils, CC grade). We blended 270 g of carbon nanotubes and 730 g of EVA (Quantum Microthene FE530) in a lab mixer. The nanotube-EVA blend was compounded, pelletized, and extruded (Brabender PL2000 Plasti-Corder) to produce a continuous ribbon (∼ 15 cm wide, ∼ 1 mm thick) of nanotube-EVA composite.
  • 33
    • 0042339530 scopus 로고    scopus 로고
    • note
    • SEM images of fractured samples indicated that the layer was at least 50 nm thick.
  • 34
    • 0041838378 scopus 로고    scopus 로고
    • note
    • Oxidation of nanotubes [22,23] generates oxygen-containing functional groups. We do not know the composition of these functional groups. Based on our ability to conduct N-hydroxysuccinimide (NHS)-ester couplings to the surface (Scheme 1), we hypothesized that carboxylic acid groups were present. FTIR showed no measurable signal for carbonyls. Since EVA contains oxygen, we were unable were unable to use X-ray photon spectroscopy (XPS) to measure additional oxygen introduced by oxidation of the surface.
  • 35
    • 0042339534 scopus 로고    scopus 로고
    • note
    • The majority of the streptavidin was covalently coupled. Composites that were oxidized and activated with NHS-esters bound three times as much streptavidin as did composites that were oxidized but not NHS-ester activated.
  • 36
    • 0042840489 scopus 로고    scopus 로고
    • note
    • A two-dimensional protein crystal of streptavidin (effectively a close-packed monolayer of streptavidin) has 2.3 pmol streptavidin per square centimeter. We calculated this number from experimental data in reference [36].
  • 38
    • 0042840490 scopus 로고    scopus 로고
    • note
    • 2+ was replaced with the suspension of the antibody adsorbed on colloidal gold.
  • 39
    • 0041838384 scopus 로고    scopus 로고
    • note
    • -1. A plot of the ECL signal from the bound label versus potential showed a peak at approximately 1.1 V. We report the total integrated current measured at the luminometer.
  • 40
    • 0041838383 scopus 로고    scopus 로고
    • note
    • -1, ∼ 290 nM) See [40].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.