Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: Role of 5-HT 1A receptors

British Journal of Pharmacology

Volumn 139, Issue 7, 2003, Pages 1281-1288

  Invernizzi, Roberto William ^a   Sacchetti, Giuseppina ^a   Parini, Stefania ^a   Acconcia, Sabrina ^a   Samanin, Rosario ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

5 HT 1A receptors; 5 HT 2A receptors; 5 Hydroxytryptamine; Antidepressant drugs; Dopamine; Dorsal raphe; Microdialysis; Noradrenaline; Prefrontal cortex; Ventral hippocampus

Indexed keywords

DOPAMINE; FLIBANSERIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NORADRENALIN; SEROTONIN;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BRAIN LEVEL; BRAIN REGION; CONTROLLED STUDY; DIALYSATE; DORSAL RAPHE NUCLEUS; DOSE RESPONSE; DRUG BINDING; DRUG RECEPTOR BINDING; EXTRACELLULAR SPACE; HIPPOCAMPUS; IN VIVO STUDY; MALE; MICRODIALYSIS; NONHUMAN; PREFRONTAL CORTEX; PSYCHOPHARMACOLOGY; RAT;

ANIMALS; ANTIDEPRESSIVE AGENTS; BENZIMIDAZOLES; DOPAMINE; EXTRACELLULAR FLUID; FORECASTING; HIPPOCAMPUS; INJECTIONS, SUBCUTANEOUS; MALE; MICRODIALYSIS; NOREPINEPHRINE; PIPERAZINES; PREFRONTAL CORTEX; PYRIDINES; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN;

EID: 0041385717     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705341     Document Type: Article

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