Clozapine, haloperidol, and the D4 antagonist PNU-101387G: In vivo effects on mesocortical, mesolimbic, and nigrostriatal dopamine and serotonin release

Journal of Neural Transmission

Volumn 105, Issue 6-7, 1998, Pages 749-767

  Broderick, P A ^a,b   Piercey, M F ^c  

^a CITY UNIVERSITY OF NEW YORK MEDICAL SCHOOL   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

^c PFIZER INC   (United States)

Author keywords

5 HT2 receptor; A10 neural pathways; A9 neural pathways; Antipsychotic agents; Carbon paste microelectrodes; Caudate putamen (dorsal striatum); Clozapine; D2 receptor; D4 receptor; Dopamine; Dopamine receptor antagonists; Extrapyramidal symptoms (EPS); Haloperidol; In vivo electrochemistry; In vivo microvoltammetry; Motor disorders; Neuroleptics; Nucleus accumbens; PNU 101387G; Prefrontal cortex; Psychosis; Schizophrenia; Serotonin; Serotonin receptor antagonists

Indexed keywords

CLOZAPINE; DOPAMINE; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; HALOPERIDOL; SEROTONIN; SONEPIPRAZOLE; UNCLASSIFIED DRUG; DOPAMINE 2 RECEPTOR; DRD4 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CAUDATE NUCLEUS; CONTROLLED STUDY; DOPAMINE RELEASE; DRUG EFFECT; LIMBIC CORTEX; MALE; NEUROCHEMISTRY; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; PUTAMEN; RAT; SEROTONIN RELEASE; ANIMAL; BRAIN; CORPUS STRIATUM; DRUG ANTAGONISM; LIMBIC SYSTEM; METABOLISM; OSMOLARITY; SPRAGUE DAWLEY RAT; SUBSTANTIA NIGRA; TISSUE DISTRIBUTION;

ANIMALS; BRAIN; CEREBRAL CORTEX; CLOZAPINE; CORPUS STRIATUM; DOPAMINE; DOPAMINE ANTAGONISTS; HALOPERIDOL; LIMBIC SYSTEM; MALE; OSMOLAR CONCENTRATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; SEROTONIN; SUBSTANTIA NIGRA; TISSUE DISTRIBUTION;

EID: 0031593975     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007020050093     Document Type: Article

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