Proline residue 280 in the second extracellular loop (EC2) of the VPAC2 receptor is essential for the receptor structure

Peptides

Volumn 22, Issue 9, 2001, Pages 1363-1370

  Vertongen, P ^a   Solano, R M ^a   Juarranz, M G ^a   Perret, J ^a   Waelbroeck, M ^a   Robberecht, P ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Adenylate cyclase activity; VPAC1 receptor; VPAC2 receptor

Indexed keywords

ADENYLATE CYCLASE; GLYCINE; LIGAND; PROLINE; PROTEIN VPAC1 RECEPTOR; PROTEIN VPAC1 RECEPTOR ANTAGONIST; PROTEIN VPAC2 RECEPTOR; RECEPTOR BLOCKING AGENT; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC PROCEDURES; HUMAN; LIGAND BINDING; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STRUCTURE;

ADENYLATE CYCLASE; AMINO ACID SUBSTITUTION; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; BINDING, COMPETITIVE; CELL MEMBRANE; CELLS, CULTURED; CHO CELLS; CONSERVED SEQUENCE; CRICETINAE; CRICETULUS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HELIX-LOOP-HELIX MOTIFS; HUMANS; LIGANDS; MUTAGENESIS, SITE-DIRECTED; PROLINE; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE, TYPE II; RECEPTORS, VASOACTIVE INTESTINAL POLYPEPTIDE, TYPE I; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0034888810     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00476-4     Document Type: Article

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