Activation of neuronal nitric-oxide synthase by the 5-methyl analog of tetrahydrobiopterin: Functional evidence against reductive oxygen activation by the pterin cofactor

Journal of Biological Chemistry

Volumn 274, Issue 23, 1999, Pages 16047-16051

  Riethmüller, Christoph ^a   Gorren, Antonius C F ^a   Pitters, Eva ^a   Hemmens, Benjamin ^a   Habisch, Hans Jörg ^a   Heales, Simon J R ^b   Schmidt, Kurt ^a   Werner, Ernst R ^c   Mayer, Bernd ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^c Center for Molecular Biosciences Innsbruck   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

HEME DERIVATIVE; NITRIC OXIDE SYNTHASE; OXYGENASE; TETRAHYDROBIOPTERIN;

ANIMAL CELL; ARTICLE; BINDING SITE; BIOSYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STABILITY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; STEADY STATE;

ANIMALS; BINDING SITES; BIOPTERIN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; NERVE TISSUE PROTEINS; NEURONS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; OXIDATION-REDUCTION; OXYGEN; OXYGEN CONSUMPTION; PTERINS; RATS; SPODOPTERA; SUPEROXIDES;

ANIMALIA; LETHRINIDAE;

EID: 0039425194     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.23.16047     Document Type: Article

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