Direct measurement of nitric oxide generation from nitric oxide synthase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 23, 1997, Pages 12705-12710

  Xia, Yong ^a   Zweier, Jay L ^a,b  

^a JOHNS HOPKINS BAYVIEW MEDICAL CENTER   (United States)

^b JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Electron paramagnetic resonance; L citrulline; L arginine; Spin trapping; Superoxide

Indexed keywords

ARGININE; CITRULLINE; FREE RADICAL; NITRIC OXIDE SYNTHASE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ARTICLE; CATALYSIS; ELECTRON SPIN RESONANCE; ELECTRON TRANSPORT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PURIFICATION; HYPOTHESIS; PRIORITY JOURNAL; SPIN TRAPPING;

CELL LINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 0030840366     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.23.12705     Document Type: Article

References (28)

1. Moncada, S., Palmer, R. M. & Higgs, E. A. (1991) Pharmacol. Rev. 43, 109-142.
2. Gross, S. S. & Wolin, M. S. (1995) Annu. Rev. Physiol. 57, 737-769.
3. Bredt, D. S. & Snyder, S. H. (1991) Annu. Rev. Biochem. 63, 175-195.
4. Nathan, C. & Xie, Q.-w. (1994) Cell 78, 915-918.
5. Marietta, M. A. (1993) J. Biol. Chem. 268, 12231-12234.
6. Griffith, O. W. & Stuehr, D. J. (1995) Annu. Rev. Physiol. 57, 707-736.
7. Stamler, J. S., Singel, D. J. & Loscalzo J. (1992) Science 258, 1898-1902.
8. Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A. & Freeman, B. A. (1990) Proc. Natl. Acad. Sci. USA 87, 1620-1624.
9. Schmidt, H. H. H. W., Hofmann, H., Schindler, U., Shutenko, Z. S., Cunningham, D. D. & Feelisch, M. (1996) Proc. Natl. Acad. Sci. USA 93, 14492-14497.
10. Shinobu, L. A., Jones, S. G. & Jones, M. M. (1984) Acta Pharmacol. Toxicol. 54, 189-194.
11. Field, L., Dilts, R. V., Ravichandaran, R., Lanhert, P. G. & Carnahan, G. E. (1978) J. Chem. Soc. Chem. Commun. 249-250.
12. Smith, P. A. S. & Hein, G. E. (1960) J. Am. Chem. Soc. 82, 5731-5740.
13. Pou, S., Pou, W. S., Bredt, D. S., Snyder, S. H. & Rosen, G. M. (1992) J. Biol. Chem. 267, 24173-24176.
14. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
15. Komarov, A., Mattson, D., Jones, M. M., Singh, P. K. & Lai, C. S. (1993) Biochem. Biophys. Res. Commun. 195, 1191-1198.
16. Zweier, J. L., Wang, P., Samouilov, A. & Kuppusamy, P. (1995) Nat. Med. 1, 804-809.
17. Xia, Y., Dawson, V. L., Dawson, T. M., Snyder, S. H. & Zweier, J. L. (1996) Proc. Natl. Acad. Sci. USA 93, 6770-6774.
18. Zweier, J. L., Wang, P. & Kuppusamy, P. (1995) J. Biol. Chem. 270, 304-307.
19. Bredt, D. S. & Snyder, S. H. (1989) Proc. Natl. Acad. Sci. USA 86, 9030-9033.
20. Vanin, A. F. Mordvintcev, P. I., Hauschildt, S. & Mulsch, A. (1993) Biochim. Biophys. Acta 1177, 37-42.
21. Finkelstein, E., Rosen, G. M. & Rauckman, E. J. (1982) Mol. Pharmacol. 21, 262-265.
22. Mayer, B., Klatt, P., Werner, E. R. & Schidt, K. (1995) J. Biol. Chem. 270, 655-659.
23. Palmer, R. M. J., Ashton, D. S. & Moncada, S. (1988) Nature (London) 333, 664-666.
24. Palmer, R. M. J., Ferrige, A. G. & Moncada, S. (1987) Nature (London) 327, 524-526.
25. Malinski, T. & Taha Z. (1992) Nature (London) 358, 676-678.
26. Lancaster, J. R., Jr., Langehr, J. M., Bergonia, H. A., Murase, N., Simmons, R. L. & Hoffman, R. A. (1992) J. Biol Chem. 267, 10994-10998.
27. Heinzel, B., John, M., Klatt, P., Bohme, E. & Mayer, B. (1992) Biochem. J. 281, 627-630.
28. Iyengar, R., Stuehr, D. J. & Marietta, M. A. (1987) Proc. Natl. Acad. Sci. USA 84, 6369-6373.