메뉴 건너뛰기




Volumn 5, Issue 2, 2003, Pages 123-132

Peptide-assisted delivery of steric-blocking antisense oligomers

Author keywords

2 O methoxyethylphosphorothioate; 2 O methylphosphorothioate; Ant; Cell permeable peptides; Morpholino; PMO; PNA; SV 40; Tat

Indexed keywords

2' O ALKYL PHOSPHOROTHIOATE ANTISENSE OLIGONUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; ARGININE; DNA; OLIGOMER; PEPTIDE; PEPTIDE NUCLEIC ACID; PHOSPHORODIAMIDATE MORPHOLINO; PHOSPHOROTHIOIC ACID; TRYPSIN; UNCLASSIFIED DRUG;

EID: 0038814141     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (24)

References (47)
  • 1
    • 0032699477 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: The case for an RNase H-independent structural type
    • 1489
    • Summerton J: Morpholino antisense oligomers: The case for an RNase H-independent structural type. Biochim Biophys Acta (1999) 1489(1):141-158.
    • (1999) Biochim. Biophys. Acta. , Issue.1 , pp. 141-158
    • Summerton, J.1
  • 3
    • 0035042293 scopus 로고    scopus 로고
    • The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos
    • Kos R, Reedy MV, Johnson RL, Erickson CA: The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis in avian embryos. Development (2001) 128(8):1467-1479.
    • (2001) Development , vol.128 , Issue.8 , pp. 1467-1479
    • Kos, R.1    Reedy, M.V.2    Johnson, R.L.3    Erickson, C.A.4
  • 4
    • 0033780376 scopus 로고    scopus 로고
    • Effective targeted gene 'knockdown' in zebrafish
    • Nasevicius A, Ekker SC: Effective targeted gene 'knockdown' in zebrafish. Nat Genet (2000) 26(2):216-220.
    • (2000) Nat. Genet. , vol.26 , Issue.2 , pp. 216-220
    • Nasevicius, A.1    Ekker, S.C.2
  • 5
    • 0033811705 scopus 로고    scopus 로고
    • Intracellular delivery strategies for antisense phosphorodiamidate morpholino oligomers
    • Ghosh C, Iversen PL: Intracellular delivery strategies for antisense phosphorodiamidate morpholino oligomers. Antisense Nucleic Acid Drug Dev (2000) 10(4):263-274.
    • (2000) Antisense Nucleic Acid Drug Dev. , vol.10 , Issue.4 , pp. 263-274
    • Ghosh, C.1    Iversen, P.L.2
  • 7
    • 0034910904 scopus 로고    scopus 로고
    • Achieving efficient delivery of morpholino oligos in cultured cells
    • Morcos PA: Achieving efficient delivery of morpholino oligos in cultured cells. Genesis (2001) 30(3):94-102.
    • (2001) Genesis , vol.30 , Issue.3 , pp. 94-102
    • Morcos, P.A.1
  • 8
    • 0030862707 scopus 로고    scopus 로고
    • Morpholino antisense oligomers: Design, preparation, and properties
    • Summerton J, Weller D: Morpholino antisense oligomers: Design, preparation, and properties. Antisense Nucleic Acid Drug Dev (1997) 7:187-195.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 187-195
    • Summerton, J.1    Weller, D.2
  • 10
    • 0034897373 scopus 로고    scopus 로고
    • Morphant technology in model developmental systems
    • Ekker SC, Larson JD: Morphant technology in model developmental systems. Genesis (2001) 30(3):89-93.
    • (2001) Genesis , vol.30 , Issue.3 , pp. 89-93
    • Ekker, S.C.1    Larson, J.D.2
  • 11
    • 0012738916 scopus 로고    scopus 로고
    • Cytochrome P450 3A2 antisense morpholino oligomer AVI-4472: A 14-day toxicity study in male rats
    • Arora V, Kroeker AD, Reddy MT: Cytochrome P450 3A2 antisense morpholino oligomer AVI-4472: A 14-day toxicity study in male rats. Toxicol Sci (2002) 66:107.
    • (2002) Toxicol. Sci. , vol.66 , pp. 107
    • Arora, V.1    Kroeker, A.D.2    Reddy, M.T.3
  • 12
    • 0036805726 scopus 로고    scopus 로고
    • Transdermal use of phosphorodiamidate morpholino oligomer AVI-4472 inhibits cytochrome P450 3A2 activity in male rats
    • Arora V, Hannah TL, Iversen PL, Brand RM: Transdermal use of phosphorodiamidate morpholino oligomer AVI-4472 inhibits cytochrome P450 3A2 activity in male rats. Pharm Res (2002) 19(10):1465-1470.
    • (2002) Pharm. Res. , vol.19 , Issue.10 , pp. 1465-1470
    • Arora, V.1    Hannah, T.L.2    Iversen, P.L.3    Brand, R.M.4
  • 13
    • 0036279927 scopus 로고    scopus 로고
    • Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats
    • Arora V, Knapp DC, Reddy MT, Weller DD, Iversen PL: Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats. J Pharm Sci (2002) 91(4):1009-1018
    • (2002) J. Pharm. Sci. , vol.91 , Issue.4 , pp. 1009-1018
    • Arora, V.1    Knapp, D.C.2    Reddy, M.T.3    Weller, D.D.4    Iversen, P.L.5
  • 14
    • 0026341239 scopus 로고
    • Sequence selective recognition of DNA by strand displacement with a thymine-substituted polyamide
    • 5037
    • Nielsen PE, Egholm M, Berg RH, Buchardt O: Sequence selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science (1991) 254(5037):1497-1500.
    • (1991) Science , vol.254 , pp. 1497-1500
    • Nielsen, P.E.1    Egholm, M.2    Berg, R.H.3    Buchardt, O.4
  • 17
    • 0032998423 scopus 로고    scopus 로고
    • Keeping the biotechnology of antisense in context
    • Stein CA: Keeping the biotechnology of antisense in context. Nat Biotechnol (1999) 17(3):209.
    • (1999) Nat. Biotechnol. , vol.17 , Issue.3 , pp. 209
    • Stein, C.A.1
  • 19
    • 0034945672 scopus 로고    scopus 로고
    • Antisense effects in the cell nucleus: Modification of splicing
    • Kole R, Sazani P: Antisense effects in the cell nucleus: Modification of splicing. Curr Opin Mol Ther (2001) 3(3):229-234.
    • (2001) Curr. Opin. Mol. Ther. , vol.3 , Issue.3 , pp. 229-234
    • Kole, R.1    Sazani, P.2
  • 21
    • 0032485884 scopus 로고    scopus 로고
    • Upregulation of luciferase gene expression with antisense oligonucleotides: Implications and applications in functional assay development
    • Kang SH, Cho MJ, Kole R: Upregulation of luciferase gene expression with antisense oligonucleotides: Implications and applications in functional assay development. Biochemistry (1998) 37(18):6235-6239.
    • (1998) Biochemistry , vol.37 , Issue.18 , pp. 6235-6239
    • Kang, S.H.1    Cho, M.J.2    Kole, R.3
  • 22
    • 0036298282 scopus 로고    scopus 로고
    • Conjugates of antisense oligonucleotides with the Tat and Antennapedia cell-penetrating peptides: Effects on cellular uptake, binding to target sequences, and biologic actions
    • Astriab-Fisher A, Sergueev D, Fisher M, Shaw BR, Juliano RL: Conjugates of antisense oligonucleotides with the Tat and Antennapedia cell-penetrating peptides: Effects on cellular uptake, binding to target sequences, and biologic actions. Pharm Res (2002) 19(6):744-754.
    • (2002) Pharm. Res. , vol.19 , Issue.6 , pp. 744-754
    • Astriab-Fisher, A.1    Sergueev, D.2    Fisher, M.3    Shaw, B.R.4    Juliano, R.L.5
  • 23
    • 0035369937 scopus 로고    scopus 로고
    • Quantitation of intracellular concentration of a delivered morpholino oligomer by capillary electrophoresis-laser-induced fluorescence: Correlation with upregulation of luciferase gene expression
    • McKeon J, Cho MJ, Khaledi MG: Quantitation of intracellular concentration of a delivered morpholino oligomer by capillary electrophoresis-laser-induced fluorescence: Correlation with upregulation of luciferase gene expression. Anal Biochem (2001) 293(1):1-7.
    • (2001) Anal. Biochem. , vol.293 , Issue.1 , pp. 1-7
    • McKeon, J.1    Cho, M.J.2    Khaledi, M.G.3
  • 24
    • 0034775960 scopus 로고    scopus 로고
    • Quantitative nuclear and cytoplasmic localization of antisense oligonucleotides by capillary electrophoresis with laser-induced fluorescence detection
    • McKeon J, Khaledi MG: Quantitative nuclear and cytoplasmic localization of antisense oligonucleotides by capillary electrophoresis with laser-induced fluorescence detection. Electrophoresis (2001) 22(17):3765-3770.
    • (2001) Electrophoresis , vol.22 , Issue.17 , pp. 3765-3770
    • McKeon, J.1    Khaledi, M.G.2
  • 25
    • 0036710005 scopus 로고    scopus 로고
    • Antisense peptide nucleic acids conjugated to somatostatin analogs and targeted at the n-myc oncogene display enhanced cytotoxity to human neuroblastoma IMR32 cells expressing somatostatin receptors
    • Sun L, Fuselier JA, Murphy WA, Coy DH: Antisense peptide nucleic acids conjugated to somatostatin analogs and targeted at the n-myc oncogene display enhanced cytotoxity to human neuroblastoma IMR32 cells expressing somatostatin receptors. Peptides (2002) 23(9):1557-1565.
    • (2002) Peptides , vol.23 , Issue.9 , pp. 1557-1565
    • Sun, L.1    Fuselier, J.A.2    Murphy, W.A.3    Coy, D.H.4
  • 27
    • 0036305495 scopus 로고    scopus 로고
    • A biological transporter for the delivery of peptide nucleic acids (PNAs) to the nuclear compartment of living cells
    • Braun K, Peschke P, Pipkorn R, Lampel S, Wachmuth M, Waldeck W, Friedrich E, Debus J: A biological transporter for the delivery of peptide nucleic acids (PNAs) to the nuclear compartment of living cells. J Mol Biol (2002) 318(2):237-243.
    • (2002) J. Mol. Biol. , vol.318 , Issue.2 , pp. 237-243
    • Braun, K.1    Peschke, P.2    Pipkorn, R.3    Lampel, S.4    Wachmuth, M.5    Waldeck, W.6    Friedrich, E.7    Debus, J.8
  • 28
    • 0035135576 scopus 로고    scopus 로고
    • In vivo nuclear delivery of oligonucleotides via hybridizing bifunctional peptides
    • Brandén LJ, Christensson B, Smith CI: In vivo nuclear delivery of oligonucleotides via hybridizing bifunctional peptides. Gene Ther (2001) 8(1):84-87.
    • (2001) Gene Ther. , vol.8 , Issue.1 , pp. 84-87
    • Brandén, L.J.1    Christensson, B.2    Smith, C.I.3
  • 30
    • 0034700141 scopus 로고    scopus 로고
    • The design, synthesis and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
    • Wender PA, Mitchell DJ, Pattabiraman K, Pelkey ET, Steinman L, Rothbard JB: The design, synthesis and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters. Proc Natl Acad Sci USA (2000) 97(24):13003-13008.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.24 , pp. 13003-13008
    • Wender, P.A.1    Mitchell, D.J.2    Pattabiraman, K.3    Pelkey, E.T.4    Steinman, L.5    Rothbard, J.B.6
  • 31
    • 0035204427 scopus 로고    scopus 로고
    • A peptide carrier for the delivery of biologically active proteins into mammalian cells
    • Morris MC, Depollier J, Mery J, Heitz F, Divita G: A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat Biotechnol (2001) 19(12):1173-1176.
    • (2001) Nat. Biotechnol. , vol.19 , Issue.12 , pp. 1173-1176
    • Morris, M.C.1    Depollier, J.2    Mery, J.3    Heitz, F.4    Divita, G.5
  • 32
    • 0036200148 scopus 로고    scopus 로고
    • Anti-TAR polyamide nucleotide analog conjugated with a membrane-permeating peptide inhibits human immunodeficiency virus type 1 production
    • Kaushik N, Basu A, Palumbo P, Myers RL, Pandey VN: Anti-TAR polyamide nucleotide analog conjugated with a membrane-permeating peptide inhibits human immunodeficiency virus type 1 production. J Virol (2002) 76(8):3881-3891.
    • (2002) J. Virol. , vol.76 , Issue.8 , pp. 3881-3891
    • Kaushik, N.1    Basu, A.2    Palumbo, P.3    Myers, R.L.4    Pandey, V.N.5
  • 33
    • 0035863391 scopus 로고    scopus 로고
    • Synthetic protein transduction domains: Enhanced transduction potential in vitro and in vivo
    • Ho A, Schwarze SR, Mermelstein SJ, Waksman G, Dowdy SF: Synthetic protein transduction domains: Enhanced transduction potential in vitro and in vivo. Cancer Res (2001) 61(2):474-477.
    • (2001) Cancer Res. , vol.61 , Issue.2 , pp. 474-477
    • Ho, A.1    Schwarze, S.R.2    Mermelstein, S.J.3    Waksman, G.4    Dowdy, S.F.5
  • 34
    • 0036859952 scopus 로고    scopus 로고
    • Radiometal-labeled peptide-PNA conjugates for targeting Bcl-2 expression: Preparation, characterization, and in vitro mRNA binding
    • Lewis MR, Jia F, Gallazzi F, Wang Y, Zhang J, Shenoy N, Lever SZ, Hannink M: Radiometal-labeled peptide-PNA conjugates for targeting Bcl-2 expression: Preparation, characterization, and in vitro mRNA binding. Bioconjug Chem (2002) 13(6):1176-1180.
    • (2002) Bioconjug. Chem. , vol.13 , Issue.6 , pp. 1176-1180
    • Lewis, M.R.1    Jia, F.2    Gallazzi, F.3    Wang, Y.4    Zhang, J.5    Shenoy, N.6    Lever, S.Z.7    Hannink, M.8
  • 35
    • 0036510769 scopus 로고    scopus 로고
    • Cell permeabilization and uptake of antisense peptide-peptide nucleic acid (PNA) into Escherichia coli
    • Eriksson M, Neilsen PE, Good L: Cell permeabilization and uptake of antisense peptide-peptide nucleic acid (PNA) into Escherichia coli. J Biol Chem (2002) 277(9):7144-7147.
    • (2002) J. Biol. Chem. , vol.277 , Issue.9 , pp. 7144-7147
    • Eriksson, M.1    Neilsen, P.E.2    Good, L.3
  • 36
    • 0030904245 scopus 로고    scopus 로고
    • A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
    • Vives E, Brodin P, Lebleu B: A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem (1997) 272(25):16010-16017.
    • (1997) J. Biol. Chem. , vol.272 , Issue.25 , pp. 16010-16017
    • Vives, E.1    Brodin, P.2    Lebleu, B.3
  • 37
    • 0029982569 scopus 로고    scopus 로고
    • Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent
    • Derossi D, Calvet S, Trembleau A, Brunissen A, Chassaing G, Prochiantz A: Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent. J Biol Chem (1996) 271(30):18188-18193.
    • (1996) J. Biol. Chem. , vol.271 , Issue.30 , pp. 18188-18193
    • Derossi, D.1    Calvet, S.2    Trembleau, A.3    Brunissen, A.4    Chassaing, G.5    Prochiantz, A.6
  • 38
    • 0035937124 scopus 로고    scopus 로고
    • Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery
    • Futaki S, Suzuki T, Ohashi W, Yagami T, Tanaka S, Ueda K, Sugiura Y: Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J Biol Chem (2001) 276(8):5836-5840.
    • (2001) J. Biol. Chem. , vol.276 , Issue.8 , pp. 5836-5840
    • Futaki, S.1    Suzuki, T.2    Ohashi, W.3    Yagami, T.4    Tanaka, S.5    Ueda, K.6    Sugiura, Y.7
  • 39
    • 0037169486 scopus 로고    scopus 로고
    • Possible existence of common internalization mechanisms among arginine-rich peptides
    • Suzuki T, Futaki S, Niwa M, Tanaka S, Ueda K, Sugiura Y: Possible existence of common internalization mechanisms among arginine-rich peptides. J Biol Chem (2002) 277(4):2437-2443.
    • (2002) J. Biol. Chem. , vol.277 , Issue.4 , pp. 2437-2443
    • Suzuki, T.1    Futaki, S.2    Niwa, M.3    Tanaka, S.4    Ueda, K.5    Sugiura, Y.6
  • 40
    • 0037103242 scopus 로고    scopus 로고
    • Arginine-rich molecular transporters for drug delivery: Role of backbone spacing in cellular uptake
    • Rothbard JB, Kreider E, VanDeusen CL, Wright L, Wylie BL, Wender PA: Arginine-rich molecular transporters for drug delivery: Role of backbone spacing in cellular uptake. J Med Chem (2002) 45(17):3612-3618.
    • (2002) J. Med. Chem. , vol.45 , Issue.17 , pp. 3612-3618
    • Rothbard, J.B.1    Kreider, E.2    VanDeusen, C.L.3    Wright, L.4    Wylie, B.L.5    Wender, P.A.6
  • 41
    • 0037151062 scopus 로고    scopus 로고
    • Evaluating the specificity of antisense oligonucleotide conjugates. A DNA army analysis
    • Fisher AA, Ye D, Sergueev DS, Fisher MH, Shaw BR, Juliano RL: Evaluating the specificity of antisense oligonucleotide conjugates. A DNA army analysis. J Biol Chem (2002) 227(25):22980-22984.
    • (2002) J. Biol. Chem. , vol.227 , Issue.25 , pp. 22980-22984
    • Fisher, A.A.1    Ye, D.2    Sergueev, D.S.3    Fisher, M.H.4    Shaw, B.R.5    Juliano, R.L.6
  • 42
    • 0035800055 scopus 로고    scopus 로고
    • Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-α chain
    • Karras JG, Maier MA, Lu T, Watt A, Manoharan M: Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-α chain. Biochemistry (2001) 40(26):7853-7859.
    • (2001) Biochemistry , vol.40 , Issue.26 , pp. 7853-7859
    • Karras, J.G.1    Maier, M.A.2    Lu, T.3    Watt, A.4    Manoharan, M.5
  • 46
    • 0035207025 scopus 로고    scopus 로고
    • Pharmacokinetics and delivery of Tat and Tat-protein conjugates to tissues in vivo
    • Lee HJ, Pardridge WM: Pharmacokinetics and delivery of Tat and Tat-protein conjugates to tissues in vivo. Bioconjug Chem (2001) 12(6):995-999.
    • (2001) Bioconjug. Chem. , vol.12 , Issue.6 , pp. 995-999
    • Lee, H.J.1    Pardridge, W.M.2
  • 47
    • 0037257707 scopus 로고    scopus 로고
    • Endosomolysis by masking of a membrane-active agent (EMMA) for cytoplasmic release of macromolecules
    • Rozema DB, Ekena K, Lewis DL, Loomis AG, Wolff JA: Endosomolysis by masking of a membrane-active agent (EMMA) for cytoplasmic release of macromolecules. Bioconjug Chem (2003) 14(1):51-57.
    • (2003) Bioconjug. Chem. , vol.14 , Issue.1 , pp. 51-57
    • Rozema, D.B.1    Ekena, K.2    Lewis, D.L.3    Loomis, A.G.4    Wolff, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.