Inhibition of proliferation of PC3 cells by the branched-chain fatty acid, 12-methyltetradecanoic acid, is associated with inhibition of 5-lipoxygenase

Prostate

Volumn 55, Issue 4, 2003, Pages 281-291

  Yang, Peiying ^a   Collin, Peter ^b   Madden, Timothy ^a   Chan, Diana ^a   Sweeney Gotsch, Bridget ^a   McConkey, David ^a   Newman, Robert A ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Coastside Research ^*  (United States)

Author keywords

12 methyltetradecanoic acid; 5 lipoxygenase; Apoptosis; Prostate cancer cells

Indexed keywords

12 METHYLTETRADECANOIC ACID; 5 HYDROXYICOSATETRAENOIC ACID; ANTINEOPLASTIC AGENT; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; CASPASE 3; FATTY ACID DERIVATIVE; MYRISTIC ACID DERIVATIVE; PROPIDIUM IODIDE; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARACHIDONIC ACID METABOLISM; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL DEATH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ECHINODERM; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC 50; MORPHOLOGY; NITROBLUE TETRAZOLIUM TEST; PRIORITY JOURNAL; PROSTATE CANCER; STAINING;

ANIMALS; APOPTOSIS; ARACHIDONATE 5-LIPOXYGENASE; CASPASE 3; CASPASES; CELL DIVISION; CYCLOOXYGENASE INHIBITORS; ENZYME ACTIVATION; ENZYME INHIBITORS; FATTY ACIDS; FEMALE; FLOW CYTOMETRY; GROWTH INHIBITORS; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; MALE; MICROSCOPY, ELECTRON, SCANNING; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTATIC NEOPLASMS; RATS; TUMOR CELLS, CULTURED;

EID: 0038813761     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/pros.10243     Document Type: Article

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