-
1
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine A.J. 1997. p53, the cellular gatekeeper for growth and division. Cell. 88, 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
2
-
-
0032192140
-
The complexity of p53 modulation: Emerging patterns from divergent signals
-
Giaccia A.J., Kastan M.B. 1998. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12, 2973-2983.
-
(1998)
Genes Dev.
, vol.12
, pp. 2973-2983
-
-
Giaccia, A.J.1
Kastan, M.B.2
-
3
-
-
0032931517
-
The p53 pathway
-
Prives C., Hall P.A. 1999. The p53 pathway. J. Path. 187, 112-126.
-
(1999)
J. Path.
, vol.187
, pp. 112-126
-
-
Prives, C.1
Hall, P.A.2
-
4
-
-
0003979231
-
The function of the p53 gene: A choice between life and death
-
Chumakov P.M. 2000. The function of the p53 gene: A choice between life and death. Biokhimiya. 65, 34-47.
-
(2000)
Biokhimiya
, vol.65
, pp. 34-47
-
-
Chumakov, P.M.1
-
5
-
-
0033230581
-
The cellular response to p53: The decision between life and death
-
Sionov R.V., Haupt Y. 1999. The cellular response to p53: the decision between life and death. Oncogene. 18, 6145-6157.
-
(1999)
Oncogene
, vol.18
, pp. 6145-6157
-
-
Sionov, R.V.1
Haupt, Y.2
-
7
-
-
0031987277
-
Regulation of p53 downstream genes
-
el-Deiry W.S. 1998. Regulation of p53 downstream genes. Semin. Cancer Biol. 8, 345-357.
-
(1998)
Semin. Cancer Biol.
, vol.8
, pp. 345-357
-
-
El-Deiry, W.S.1
-
8
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower L.A., Harvey M., Slagle B.L., McArthur M.J., Montgomery C.A. Jr., Butel J.S., Bradley A. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature. 356, 215-221.
-
(1992)
Nature
, vol.356
, pp. 215-221
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery Jr., C.A.5
Butel, J.S.6
Bradley, A.7
-
9
-
-
0030639352
-
p53 gene alterations in human tumors: Perspectives for cancer control
-
Hollstein M., Soussi T., Thomas G., von Brevem M.C., Bartsch. 1997. p53 gene alterations in human tumors: perspectives for cancer control. Recent Results Cancer Res. 143, 369-389.
-
(1997)
Recent Results Cancer Res.
, vol.143
, pp. 369-389
-
-
Hollstein, M.1
Soussi, T.2
Thomas, G.3
Von Brevem, M.C.4
Bartsch5
-
10
-
-
0030752030
-
Database of p53 gene somatic mutations in human tumors and cell lines: Undated compilation and future prospects
-
Hainaut P., Soussi T., Shomer B., Hollstein M., Greenblatt M., Hoving E., Harris C.C., Montesano R. 1997. Database of p53 gene somatic mutations in human tumors and cell lines: undated compilation and future prospects. Nucleic Acids Res. 1, 151-157.
-
(1997)
Nucleic Acids Res.
, vol.1
, pp. 151-157
-
-
Hainaut, P.1
Soussi, T.2
Shomer, B.3
Hollstein, M.4
Greenblatt, M.5
Hoving, E.6
Harris, C.C.7
Montesano, R.8
-
11
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M., Lin A.W., McCurrach M.E., Beach D., Lowe S.W. 1997. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell. 88, 593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
12
-
-
0032892932
-
Activation of p53 by oncogenes
-
Lowe S.W. 1999. Activation of p53 by oncogenes. Endocrine-Related Cancer. 6, 45-48.
-
(1999)
Endocrine-Related Cancer
, vol.6
, pp. 45-48
-
-
Lowe, S.W.1
-
14
-
-
0032541650
-
Increasing complexity of Ras signaling
-
Campbell S.L., Khosravi-Far R., Rossman K.L., Clark G.J., Der C.J. 1998. Increasing complexity of Ras signaling. Oncogene. 17, 1395-1413.
-
(1998)
Oncogene
, vol.17
, pp. 1395-1413
-
-
Campbell, S.L.1
Khosravi-Far, R.2
Rossman, K.L.3
Clark, G.J.4
Der, C.J.5
-
15
-
-
0034644537
-
Ras and Rho GTPases: A family reunion
-
Bar-Sagi D., Hall A. 2000. Ras and Rho GTPases: a family reunion. Cell. 103, 227-238.
-
(2000)
Cell
, vol.103
, pp. 227-238
-
-
Bar-Sagi, D.1
Hall, A.2
-
16
-
-
0001139669
-
Ras pathways to cell cycle control and cell transformation
-
Malumbres M., Pellicer A. 1998. Ras pathways to cell cycle control and cell transformation. Front Biosci. 3, 887-912.
-
(1998)
Front Biosci.
, vol.3
, pp. 887-912
-
-
Malumbres, M.1
Pellicer, A.2
-
17
-
-
0033793874
-
Ras proteins in the control of the cell cycle and cell differentiation
-
Crespo P., Leon J. 2000. Ras proteins in the control of the cell cycle and cell differentiation. Cell Mol. Life Sci. 57, 1613-1636.
-
(2000)
Cell Mol. Life Sci.
, vol.57
, pp. 1613-1636
-
-
Crespo, P.1
Leon, J.2
-
18
-
-
0024376173
-
Ras oncogenes and human cancer: A review
-
Bos J.L. 1989. Ras oncogenes and human cancer: a review. Cancer Res. 49, 4682-4689.
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
19
-
-
0026909770
-
Ras and human tumors
-
Rodenhuis S. 1992. ras and human tumors. Semin. Cancer Biol. 3, 241-247.
-
(1992)
Semin. Cancer Biol.
, vol.3
, pp. 241-247
-
-
Rodenhuis, S.1
-
20
-
-
0020520516
-
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
-
Land H., Parada L.F., Weinberg R.A. 1983. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. 304, 596-602.
-
(1983)
Nature
, vol.304
, pp. 596-602
-
-
Land, H.1
Parada, L.F.2
Weinberg, R.A.3
-
21
-
-
0022486653
-
In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes
-
Franza B.R., Maruyama K., Garrels J.I., Ruley H.E. 1986. In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell. 44, 409-418.
-
(1986)
Cell
, vol.44
, pp. 409-418
-
-
Franza, B.R.1
Maruyama, K.2
Garrels, J.I.3
Ruley, H.E.4
-
22
-
-
0026074818
-
Cooperation between oncogenes
-
Hunter T. 1991. Cooperation between oncogenes. Cell. 64, 249-270.
-
(1991)
Cell
, vol.64
, pp. 249-270
-
-
Hunter, T.1
-
23
-
-
0026072464
-
Mechanisms of oncogene cooperation: Activation and inactivation of a growth antagonist
-
Ragozzino M.M., Kuo A., DeGregori J., Kohl N., Ruley H.E. 1991. Mechanisms of oncogene cooperation: activation and inactivation of a growth antagonist. Environ. Health Perspect. 93, 97-103.
-
(1991)
Environ. Health Perspect.
, vol.93
, pp. 97-103
-
-
Ragozzino, M.M.1
Kuo, A.2
DeGregori, J.3
Kohl, N.4
Ruley, H.E.5
-
24
-
-
0036561908
-
Modelling the molecular circuitry of cancer
-
Hahn W.C., Weinberg R.A. 2002. Modelling the molecular circuitry of cancer. Nat. Rev. Cancer. 5, 331-341.
-
(2002)
Nat. Rev. Cancer
, vol.5
, pp. 331-341
-
-
Hahn, W.C.1
Weinberg, R.A.2
-
27
-
-
0032190629
-
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
-
Lin A.W., Barradas M., Stone J.C., van Aelst L., Serrano M., Lowe S.W. 1998. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev. 12, 3008-3019.
-
(1998)
Genes Dev.
, vol.12
, pp. 3008-3019
-
-
Lin, A.W.1
Barradas, M.2
Stone, J.C.3
Van Aelst, L.4
Serrano, M.5
Lowe, S.W.6
-
28
-
-
0032192153
-
Senescence of human fibroblasts induced by oncogenic Raf
-
Zhu J., Woods D., McMahon M., Bishop J.M. 1998. Senescence of human fibroblasts induced by oncogenic Raf. Genes Dev. 12, 2997-3007.
-
(1998)
Genes Dev.
, vol.12
, pp. 2997-3007
-
-
Zhu, J.1
Woods, D.2
McMahon, M.3
Bishop, J.M.4
-
29
-
-
0033517357
-
Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras
-
Pantoja C, Serrano M. 1999. Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras. Oncogene. 18, 4974-4982.
-
(1999)
Oncogene
, vol.18
, pp. 4974-4982
-
-
Pantoja, C.1
Serrano, M.2
-
31
-
-
0025969355
-
Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest
-
Hicks G.G., Egan S.E., Greenberg A.H., Mowat M. 1991. Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest. Mol. Cell. Biol. 11, 1344-1352.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1344-1352
-
-
Hicks, G.G.1
Egan, S.E.2
Greenberg, A.H.3
Mowat, M.4
-
32
-
-
0033637086
-
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
-
Sage J., Mulligan G.J., Attardi L.D., Miller A., Chen S., Williams B., Theodorou E., Jacks T. 2000. Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev. 14, 3037-3050.
-
(2000)
Genes Dev.
, vol.14
, pp. 3037-3050
-
-
Sage, J.1
Mulligan, G.J.2
Attardi, L.D.3
Miller, A.4
Chen, S.5
Williams, B.6
Theodorou, E.7
Jacks, T.8
-
33
-
-
0025142733
-
Transforming collaborations between ras and nuclear oncogenes
-
Ruley H.E. 1990. Transforming collaborations between ras and nuclear oncogenes. Cancer Cells. 2, 258-268.
-
(1990)
Cancer Cells
, vol.2
, pp. 258-268
-
-
Ruley, H.E.1
-
34
-
-
0040433650
-
Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene
-
Hirakawa T., Ruley H.E. 1988. Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene. Proc. Natl. Acad. Sci. USA. 85, 1519-1523.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 1519-1523
-
-
Hirakawa, T.1
Ruley, H.E.2
-
35
-
-
0022654125
-
Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells
-
Zerler B., Moran B., Maruyama K., Moomaw J., Grodzicker T., Ruley H.E. 1986. Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells. Mol. Cell. Biol. 6, 887-899.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 887-899
-
-
Zerler, B.1
Moran, B.2
Maruyama, K.3
Moomaw, J.4
Grodzicker, T.5
Ruley, H.E.6
-
36
-
-
0023629979
-
Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes
-
Kohl N.E., Ruley H.E. 1987. Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes. Oncogene. 2, 41-48.
-
(1987)
Oncogene
, vol.2
, pp. 41-48
-
-
Kohl, N.E.1
Ruley, H.E.2
-
37
-
-
0031806044
-
The molecular role of Myc in growth and transformation: Recent discoveries lead to new insights
-
Facchini M.L., Penn L.Z. 1998. The molecular role of Myc in growth and transformation: recent discoveries lead to new insights. FASEB J. 12, 633-651
-
(1998)
FASEB J.
, vol.12
, pp. 633-651
-
-
Facchini, M.L.1
Penn, L.Z.2
-
38
-
-
0034663873
-
PML is induced by oncogenic ras and promotes premature senescence
-
Ferbeyre G., de Stanchina E., Querido E., Baptiste N., Prives C., Lowe S.W. 2000. PML is induced by oncogenic ras and promotes premature senescence. Genes Dev. 14, 2015-2027.
-
(2000)
Genes Dev.
, vol.14
, pp. 2015-2027
-
-
Ferbeyre, G.1
De Stanchina, E.2
Querido, E.3
Baptiste, N.4
Prives, C.5
Lowe, S.W.6
-
39
-
-
0036237039
-
Oncogenic ras and p53 cooperate to induce cellular senescence
-
Ferbeyre G., de Stanchina E., Lin A.W., Querido E., McCurrach M.E., Hannon G.J., Lowe S.W. 2002. Oncogenic ras and p53 cooperate to induce cellular senescence. Mol. Cell. Biol. 10, 3497-3508.
-
(2002)
Mol. Cell. Biol.
, vol.10
, pp. 3497-3508
-
-
Ferbeyre, G.1
De Stanchina, E.2
Lin, A.W.3
Querido, E.4
McCurrach, M.E.5
Hannon, G.J.6
Lowe, S.W.7
-
40
-
-
0023219816
-
Biological effects of a murine retrovirus carrying an activated N-ras gene of human origin
-
Souyri M., Koehne C.F., O'Donnell P.V., Aldrich T.H., Furth M.E., Fleissner E. 1987. Biological effects of a murine retrovirus carrying an activated N-ras gene of human origin. Virology. 158, 69-78.
-
(1987)
Virology
, vol.158
, pp. 69-78
-
-
Souyri, M.1
Koehne, C.F.2
O'Donnell, P.V.3
Aldrich, T.H.4
Furth, M.E.5
Fleissner, E.6
-
41
-
-
0025352187
-
Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
-
Morgenstern J.P., Land H. 1990. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res. 18, 3587-3596.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 3587-3596
-
-
Morgenstern, J.P.1
Land, H.2
-
42
-
-
0029840667
-
Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains
-
Ossovskaya V.S., Mazo I.A., Chernov M.V., Chernova O.B., Strezoska Z., Kondratov R., Stark G.R., Chumakov P.M., Gudkov A.V. 1996. Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains. Proc. Natl. Acad. Sci. USA. 93, 10 309-10 314.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10309-10314
-
-
Ossovskaya, V.S.1
Mazo, I.A.2
Chernov, M.V.3
Chernova, O.B.4
Strezoska, Z.5
Kondratov, R.6
Stark, G.R.7
Chumakov, P.M.8
Gudkov, A.V.9
-
43
-
-
0031984816
-
High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein
-
Grignani F., Kinsella T., Mencarelli A., Valtieri M., Riganelli D., Lanfrancone L., Peschle C., Nolan G.P., Pelicci P.G. 1998. High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein. Cancer Res. 58, 14-19.
-
(1998)
Cancer Res.
, vol.58
, pp. 14-19
-
-
Grignani, F.1
Kinsella, T.2
Mencarelli, A.3
Valtieri, M.4
Riganelli, D.5
Lanfrancone, L.6
Peschle, C.7
Nolan, G.P.8
Pelicci, P.G.9
-
44
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promotors
-
Gossen M., Bujard H. 1992. Tight control of gene expression in mammalian cells by tetracycline-responsive promotors. Proc. Natl. Acad. Sci. USA. 89, 5547-5551.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
45
-
-
0004136246
-
-
N.Y., Cold Spring Harbor: Cold Spring Harbor Laboratory
-
Sambroock J., Fritsch E.F., Maniatis. T. 1989. Molecular Cloning: A Laboratory Manual, 2nd ed., N.Y., Cold Spring Harbor: Cold Spring Harbor Laboratory.
-
(1989)
Molecular Cloning: A Laboratory Manual, 2nd Ed.
-
-
Sambroock, J.1
Fritsch, E.F.2
Maniatis, T.3
-
46
-
-
0033552595
-
Regulation of p53 in response to DNA damage
-
Lakin N.D., Jackson S.P. 1999. Regulation of p53 in response to DNA damage. Oncogene. 18, 7644-7655.
-
(1999)
Oncogene
, vol.18
, pp. 7644-7655
-
-
Lakin, N.D.1
Jackson, S.P.2
-
47
-
-
0029704568
-
Transcription factors C-ERB and AP-1 modulate the promoter activity of the regulatory region of the human p53 gene
-
Kukushkin A.N., Svetlikova S.B., Belov D.N., Slepneva N.I., Pospelov V.A. 1996. Transcription factors C-ERB and AP-1 modulate the promoter activity of the regulatory region of the human p53 gene. Mol. Biol. 30, 93-103.
-
(1996)
Mol. Biol.
, vol.30
, pp. 93-103
-
-
Kukushkin, A.N.1
Svetlikova, S.B.2
Belov, D.N.3
Slepneva, N.I.4
Pospelov, V.A.5
-
48
-
-
0033614370
-
Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kappaB and Myc/Max
-
Kirch H.C., Flaswinkel S., Rumpf H., Brockmann D., Esche H. 1999. Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kappaB and Myc/Max. Oncogene. 18, 2728-2738.
-
(1999)
Oncogene
, vol.18
, pp. 2728-2738
-
-
Kirch, H.C.1
Flaswinkel, S.2
Rumpf, H.3
Brockmann, D.4
Esche, H.5
-
49
-
-
0033768035
-
Characterization of a nuclear factor that binds to AP1-like element in the rat p53 promoter during liver regeneration
-
Lee M., Yu S., Park J.S. 2000. Characterization of a nuclear factor that binds to AP1-like element in the rat p53 promoter during liver regeneration. J. Cell Biochem. 80, 124-132.
-
(2000)
J. Cell Biochem.
, vol.80
, pp. 124-132
-
-
Lee, M.1
Yu, S.2
Park, J.S.3
-
50
-
-
0035971493
-
AP-1 in cell proliferation and survival
-
Shaulian E, Karin M. 2001. AP-1 in cell proliferation and survival. Oncogene. 20, 2390-2400.
-
(2001)
Oncogene
, vol.20
, pp. 2390-2400
-
-
Shaulian, E.1
Karin, M.2
-
51
-
-
0030886015
-
Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53
-
Sugrue, M.M., Shin D.Y., Lee S.W., Aaronson S.A. 1997. Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53. Proc. Natl. Acad. Sci. USA. 94, 9648-9653.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9648-9653
-
-
Sugrue, M.M.1
Shin, D.Y.2
Lee, S.W.3
Aaronson, S.A.4
|