Selective activation of the calcium signaling pathway by altered peptide ligands

Journal of Experimental Medicine

Volumn 184, Issue 4, 1996, Pages 1525-1530

  Sloan Lancaster, Joanne ^a   Steinberg, Thomas H ^a   Allen, Paul M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; EGTAZIC ACID; IONOMYCIN; LIGAND; PEPTIDE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CLONAL ANERGY; CONTROLLED STUDY; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEMOGLOBINS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED CBA; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TIME FACTORS;

EID: 0029952074     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.4.1525     Document Type: Article

References (29)

1. Klausner, R.D., and L.E. Samelson. 1991. T cell antigen receptor activation pathways: the tyrosine kinase connection. Cell. 64:875-878.
2. Weiss, A., and D.R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell. 76:263-274.
3. Reth, M. 1989. Antigen receptor tail clue. Nature (Lond.). 338:383-384.
4. Samelson, L.E., and R.D. Klausner. 1992. Tyrosine kinases and tyrosine-based activation motifs. J. Biol. Chem. 267:24913-24916.
5. Chan, A.C., D.M. Desai, and A. Weiss. 1994. The role of protein tyrosine kinases and protein tyrosine phoshatases in T cell antigen receptor signal transduction. Annu. Rev. Immunol. 12:555-592.
6. Letourneur, F., and R.D. Klausner. 1992. Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 ∈. Science (Wash. DC). 255:79-82.
7. Wegener, A.-M.K., F. Letourneur, A. Hoeveler, T. Brocker. F. Luton, and B. Malissen. 1992. The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell. 68:83-95.
8. Irving, B.A., and A. Weiss. 1991. The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell. 64:891-901.
9. Jameson, S.C., and M.J. Bevan. 1995. T cell receptor antagonists and partial agonists. Immunity. 2:1-11.
10. Germain, R.N., E.H. Levine, and J. Madrenas. 1995. The T-cell receptor as a diverse signal transduction machine. The Immunologist. 3:113-121.
11. Sloan-Lancaster, J., and P.M. Allen. 1996. Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology. Annu. Rev. Immunol. 14:1-27.
12. Sloan-Lancaster, J., A.S. Shaw, J.B. Rothbard, and P.M. Allen. 1994. Partial T cell signaling: altered phospho-ζ and lack of Zap 70 recruitment in APL-induced T cell anergy. Cell. 79:913-922.
13. Madrenas, J., R.L. Wange, J.L. Wang, N. Isakov, L.E. Samelson, and R.N. Germain. 1995. ζ Phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science (Wash. DC). 267:515-518.
14. Sloan-Lancaster, J., B.D. Evavold, and P.M. Allen. 1994. Th2 cell clonal anergy as a consequence of partial activation. J. Exp. Med. 180:1195-1205.
15. Lorenz, R.G., and P.M. Allen. 1989. Thymic cortical epithelial cells lack full capacity for antigen presentation. Nature (Lond.). 340:557-559.
16. Ronchese, F., R.H. Schwartz, and R.N. Germain. 1987. Functionally distinct subsites on a class II major histocompatibility complex molecule. Nature (Lond.). 329:254-256.
17. Sloan-Lancaster, J., B.D. Evavold, and P.M. Allen. 1993. Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells. Nature (Lond.). 363:156-159.
18. Mueller, D.L., M.K. Jenkins, L. Chiodetti, and R.H. Schwartz. 1990. An intracellular calcium increase and protein kinase C activation fail to initiate T cell proliferation in the absence of a costimulatory signal. J. Immunol. 144:3701-3709.
19. Donnadieu, E., D. Cefai, Y.P. Tan, G. Paresys, G. Bismuth, and A. Trautmann. 1992. Imaging early steps of human T cell activation by antigen-presenting cells. J. Immunol. 148:2643-2653.
20. Donnadieu, E., G. Bismuth, and A. Trautmann. 1994. Antigen recognition by helper T cells elicits a sequence of distinct changes of their shape and intracellular calcium. Current Biology. 4:584-595.
21. Valitutti, S., M. Dessing, K. Aktories, H. Gallati, and A. Lanzavecchia. 1995. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. J. Exp. Med. 181:577-584.
22. Evavold, B.D., S.G. Williams, B.L. Hsu, S. Buus, and P.M. Allen. 1992. Complete dissection of the Hb(64-76) determinant using Th1, Th2 clones, and T cell hybridomas. J. Immunol. 148:347-353.
23. Alam, S.M., P.J. Travers, J.L. Wung, W. Nasholds, S. Redpath, S.C. Jameson, and N.R.J. Gascoigne. 1996. T-cell-receptor affinity and thymocyte positive selection. Nature (Lond.). 381:616-620.
24. Lyons, D.S., S.A. Lieberman, J. Hampl, J.J. Boniface, Y.-H. Chien, L.J. Berg, and M.M. Davis. 1996. A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity. 5:53-61.
25. von Boehmer, H. 1994. Positive selection of lymphocytes. Cell. 76:219-228.
26. Nossal, G.J.V. 1994. Negative selection of lymphocytes. Cell. 76:229-239.
27. fyn. Cell. 70:751-763.
28. lck in thymopoiesis. EMBO (Eur. Mol. Biol. Organ.) J. 12:1671-1680.
29. Goldsmith, M.A., and A. Weiss. 1988. Early signal transduction by the antigen receptor without commitment to T cell activation. Science (Wash. DC). 240:1029-1031.