Cerebral β-amyloid deposition is augmented by the -491AA promoter polymorphism in non-demented elderly individuals bearing the apolipoprotein E E4 allele

Acta Neuropathologica

Volumn 105, Issue 1, 2003, Pages 25-29

  Pahnke, Jens ^a   Walker, L C ^c   Schroeder, E ^b   Vogelgesang, S ^b   Stausske, D ^b   Walther, R ^b   Warzok, R W ^b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF GREIFSWALD   (Germany)

^c PFIZER INC   (United States)

Author keywords

Alzheimer's disease; Apolipoprotein E; Microglia; Risk factors; amyloid peptide

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; TAU PROTEIN; APOLIPOPROTEIN E;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DEMENTIA; DNA POLYMORPHISM; FEMALE; GENE INTERACTION; GENETIC VARIABILITY; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; MICROGLIA; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS; SENILE PLAQUE; TEMPORAL LOBE; BRAIN; GENETIC POLYMORPHISM; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; REFERENCE VALUE;

AGED; AGED, 80 AND OVER; ALLELES; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; BRAIN; FEMALE; HUMANS; MALE; MICROGLIA; MIDDLE AGED; NEUROFIBRILLARY TANGLES; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); REFERENCE VALUES;

EID: 0038730610     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-002-0602-0     Document Type: Article

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