메뉴 건너뛰기




Volumn 152, Issue 1, 1998, Pages 279-287

Two novel antifibrotics, HOE 077 and Safironil, modulate stellate cell activation in rat liver injury: Differential effects in males and females

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; ANTIFIBROTIC AGENT; CARBON TETRACHLORIDE; COLLAGEN; LUFIRONIL; MESSENGER RNA; SAFIRONIL; UNCLASSIFIED DRUG;

EID: 0031975486     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (35)

References (47)
  • 1
    • 0025359751 scopus 로고
    • Structure of the extracellular matrix in normal and fibrotic liver: Collagens and glycoproteins
    • Schuppan D: Structure of the extracellular matrix in normal and fibrotic liver: collagens and glycoproteins. Semin Liver Dis 1990, 10: 1-10
    • (1990) Semin Liver Dis , vol.10 , pp. 1-10
    • Schuppan, D.1
  • 2
    • 0002626227 scopus 로고    scopus 로고
    • Hepatic fibrosis and cirrhosis
    • Edited by Zakim D, Boyer TD. Philadelphia, WB Saunders
    • Bissell DM, Maher JJ: Hepatic fibrosis and cirrhosis. Hepatology: A Textbook of Liver Disease, ed 3, Edited by Zakim D, Boyer TD. Philadelphia, WB Saunders, 1996, pp 506-525
    • (1996) Hepatology: A Textbook of Liver Disease, Ed 3 , pp. 506-525
    • Bissell, D.M.1    Maher, J.J.2
  • 3
    • 0029006974 scopus 로고
    • Collagens: Molecular biology, diseases, and potentials for therapy
    • Prockop DJ, Kivirikko KI: Collagens: molecular biology, diseases, and potentials for therapy. Annu Rev Biochem 1995, 64:403-434
    • (1995) Annu Rev Biochem , vol.64 , pp. 403-434
    • Prockop, D.J.1    Kivirikko, K.I.2
  • 4
    • 0002748539 scopus 로고    scopus 로고
    • Fibrosis: Representative molecular elements, a basic concept, and emerging targets for suppressive treatment
    • Edited by Zakim D, Boyer TD. Philadelphia, WB Saunders
    • Hanauske-Abel HM: Fibrosis: representative molecular elements, a basic concept, and emerging targets for suppressive treatment. Hepatology: A Textbook of Liver Disease, ed 3. Edited by Zakim D, Boyer TD. Philadelphia, WB Saunders, 1996, pp 465-506
    • (1996) Hepatology: A Textbook of Liver Disease, Ed 3 , pp. 465-506
    • Hanauske-Abel, H.M.1
  • 5
    • 0020488069 scopus 로고
    • A stereochemical concept for the catalytic mechanism of prolylhydroxylase: Applicability to classification and design of inhibitors
    • Hanauske-Abel HM, Gunzler V: A stereochemical concept for the catalytic mechanism of prolylhydroxylase: applicability to classification and design of inhibitors. J Theor Biol 1982, 94:421-455
    • (1982) J Theor Biol , vol.94 , pp. 421-455
    • Hanauske-Abel, H.M.1    Gunzler, V.2
  • 6
    • 0026052004 scopus 로고
    • Effects of the prolyl 4-hydroxylase proinhibitor HOE 077 on human and rat hepatocytes in primary culture
    • Clement B, Chesne C, Satie AP, Guillouzo A: Effects of the prolyl 4-hydroxylase proinhibitor HOE 077 on human and rat hepatocytes in primary culture. J Hepatol 1991, 13(suppl 3):S41-S47
    • (1991) J Hepatol , vol.13 , Issue.3 SUPPL.
    • Clement, B.1    Chesne, C.2    Satie, A.P.3    Guillouzo, A.4
  • 8
    • 0001520008 scopus 로고
    • Hepatic lipocytes: The principal collagen-producing cells of normal rat liver
    • Friedman SL, Roll FJ, Boyles J, Bissell DM: Hepatic lipocytes: the principal collagen-producing cells of normal rat liver. Proc Natl Acad Sci USA 1985, 82:8681-8685
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 8681-8685
    • Friedman, S.L.1    Roll, F.J.2    Boyles, J.3    Bissell, D.M.4
  • 9
    • 0025000652 scopus 로고
    • Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo
    • Maher JJ, McGuire RF: Extracellular matrix gene expression increases preferentially in rat lipocytes and sinusoidal endothelial cells during hepatic fibrosis in vivo. J Clin Invest 1990, 86:1641-1648
    • (1990) J Clin Invest , vol.86 , pp. 1641-1648
    • Maher, J.J.1    McGuire, R.F.2
  • 10
    • 0026549050 scopus 로고
    • Differential expression of collagen types I, III, and IV by fat-storing (Ito) cells in vitro
    • Knittel T, Schuppan D, Meyer zum Buschenfelde KH, Ramadori G: Differential expression of collagen types I, III, and IV by fat-storing (Ito) cells in vitro. Gastroenterology 1992, 102:1724-1735
    • (1992) Gastroenterology , vol.102 , pp. 1724-1735
    • Knittel, T.1    Schuppan, D.2    Meyer Zum Buschenfelde, K.H.3    Ramadori, G.4
  • 11
    • 0021276139 scopus 로고
    • Alcoholic liver injury in baboons: Transformation of lipocytes to transitional cells
    • Mak KM, Leo MA, Lieber CS: Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells. Gastroenterology 1984, 87:188-200
    • (1984) Gastroenterology , vol.87 , pp. 188-200
    • Mak, K.M.1    Leo, M.A.2    Lieber, C.S.3
  • 12
    • 12044260143 scopus 로고
    • Seminars in medicine of the Beth Israel Hospital, Boston: The cellular basis of hepatic fibrosis: mechanisms and treatment strategies
    • Friedman SL: Seminars in medicine of the Beth Israel Hospital, Boston: the cellular basis of hepatic fibrosis: mechanisms and treatment strategies. N Engl J Med 1993, 328:1828-1835
    • (1993) N Engl J Med , vol.328 , pp. 1828-1835
    • Friedman, S.L.1
  • 13
    • 0022362862 scopus 로고
    • A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections
    • Lopez-de Leon A, Rojkind M: A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections. J Histochem Cytochem 1985, 33:737-743
    • (1985) J Histochem Cytochem , vol.33 , pp. 737-743
    • Lopez-de Leon, A.1    Rojkind, M.2
  • 14
    • 0027496798 scopus 로고
    • Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin 1
    • Housset C, Rockey DC, Bissell DM: Endothelin receptors in rat liver: lipocytes as a contractile target for endothelin 1. Proc Natl Acad Sci USA 1993, 90:9266-9270
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9266-9270
    • Housset, C.1    Rockey, D.C.2    Bissell, D.M.3
  • 15
    • 0025339713 scopus 로고
    • Transcriptional regulation of the albumin gene in cultured rat hepatocytes: Role of basement-membrane matrix
    • Bissell DM, Caron JM, Babiss LE, Friedman JM: Transcriptional regulation of the albumin gene in cultured rat hepatocytes: role of basement-membrane matrix. Mol Biol Med 1990, 7:187-197
    • (1990) Mol Biol Med , vol.7 , pp. 187-197
    • Bissell, D.M.1    Caron, J.M.2    Babiss, L.E.3    Friedman, J.M.4
  • 16
    • 0028679641 scopus 로고
    • Interferon gamma inhibits lipocyte activation and extracellular matrix mRNA expression during experimental liver injury: Implications for treatment of hepatic fibrosis
    • Rockey DC, Chung JJ: Interferon gamma inhibits lipocyte activation and extracellular matrix mRNA expression during experimental liver injury: implications for treatment of hepatic fibrosis. J Invest Med 1994, 42:660-670
    • (1994) J Invest Med , vol.42 , pp. 660-670
    • Rockey, D.C.1    Chung, J.J.2
  • 17
    • 0028596335 scopus 로고
    • Expression of variant fibronectins in wound healing: Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis
    • Jarnagin WR, Rockey DC, Koteliansky VE, Wang SS, Bissell DM: Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J Cell Biol 1994, 127:2037-2048
    • (1994) J Cell Biol , vol.127 , pp. 2037-2048
    • Jarnagin, W.R.1    Rockey, D.C.2    Koteliansky, V.E.3    Wang, S.S.4    Bissell, D.M.5
  • 18
    • 0022765968 scopus 로고
    • Primary structure of human ribosomal protein S14 and the gene that encodes it
    • Rhoads DD, Dixit A, Roufa DJ: Primary structure of human ribosomal protein S14 and the gene that encodes it. Mol Cell Biol 1986, 6:2774-2783
    • (1986) Mol Cell Biol , vol.6 , pp. 2774-2783
    • Rhoads, D.D.1    Dixit, A.2    Roufa, D.J.3
  • 19
    • 0026846805 scopus 로고
    • Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture
    • Rockey DC, Boyles JK, Gabbiani G, Friedman SL: Rat hepatic lipocytes express smooth muscle actin upon activation in vivo and in culture. J Submicrosc Cytol Pathol 1992, 24:193-203
    • (1992) J Submicrosc Cytol Pathol , vol.24 , pp. 193-203
    • Rockey, D.C.1    Boyles, J.K.2    Gabbiani, G.3    Friedman, S.L.4
  • 20
    • 0028226753 scopus 로고
    • Acetaldehyde-induced stimulation of collagen synthesis and gene expression is dependent on conditions of cell culture: Studies with rat lipocytes and fibroblasts
    • Maher JJ, Zia S, Tzagarakis C: Acetaldehyde-induced stimulation of collagen synthesis and gene expression is dependent on conditions of cell culture: studies with rat lipocytes and fibroblasts. Alcohol Clin Exp Res 1994, 18:403-409
    • (1994) Alcohol Clin Exp Res , vol.18 , pp. 403-409
    • Maher, J.J.1    Zia, S.2    Tzagarakis, C.3
  • 21
    • 0029665532 scopus 로고    scopus 로고
    • The α1β1 integrin is expressed during neointima formation in rat arteries and mediates collagen matrix reorganization
    • Gotwals PJ, Chi-Rosso G, Lindner V, Yang J, Ling L, Fawell SE, Koteliansky VE: The α1β1 integrin is expressed during neointima formation in rat arteries and mediates collagen matrix reorganization. J Clin Invest 1996, 97:2469-2477
    • (1996) J Clin Invest , vol.97 , pp. 2469-2477
    • Gotwals, P.J.1    Chi-Rosso, G.2    Lindner, V.3    Yang, J.4    Ling, L.5    Fawell, S.E.6    Koteliansky, V.E.7
  • 22
    • 0027237293 scopus 로고
    • A radioimmunoassay for the N-terminal propeptide of rat procollagen type III: Application to the study of the uptake of the N-terminal propeptide of procollagen type III in isolated perfused rat liver
    • Brocks DG, Steinert C, Gerl M, Knolle J, Neubauer HP, Gunzler V: A radioimmunoassay for the N-terminal propeptide of rat procollagen type III: application to the study of the uptake of the N-terminal propeptide of procollagen type III in isolated perfused rat liver Matrix 1993, 13:381-387
    • (1993) Matrix , vol.13 , pp. 381-387
    • Brocks, D.G.1    Steinert, C.2    Gerl, M.3    Knolle, J.4    Neubauer, H.P.5    Gunzler, V.6
  • 23
    • 0023489647 scopus 로고
    • Type IV collagen antigens in serum of rats with experimental fibrosis of the liver
    • Brocks DG, Bickel M, Engelbart K: Type IV collagen antigens in serum of rats with experimental fibrosis of the liver. Alcohol Alcoholism 1987, Suppl 1:497-500
    • (1987) Alcohol Alcoholism , Issue.1 SUPPL. , pp. 497-500
    • Brocks, D.G.1    Bickel, M.2    Engelbart, K.3
  • 24
    • 0021949370 scopus 로고
    • High-performance liquid chromatographic analysis of free hydroxyproline and proline in blood plasma and of free and peptide-bound hydroxyproline in urine
    • Palmerini CA, Fini C, Floridi A, Vedovelli A: High-performance liquid chromatographic analysis of free hydroxyproline and proline in blood plasma and of free and peptide-bound hydroxyproline in urine. J Chromatogr 1995, 339:285-292
    • (1995) J Chromatogr , vol.339 , pp. 285-292
    • Palmerini, C.A.1    Fini, C.2    Floridi, A.3    Vedovelli, A.4
  • 25
    • 0029923670 scopus 로고    scopus 로고
    • The prolyl 4-hydroxylase inhibitor HOE 077 prevents activation of Ito cells, reducing procollagen gene expression in rat liver fibrosis induced by choline-deficient L-amino acid-defined diet
    • Sakaida I, Matsumura Y, Kubota M, Kayano K, Takenaka K, Okita K: The prolyl 4-hydroxylase inhibitor HOE 077 prevents activation of Ito cells, reducing procollagen gene expression in rat liver fibrosis induced by choline-deficient L-amino acid-defined diet. Hepatology 1996, 23:755-763
    • (1996) Hepatology , vol.23 , pp. 755-763
    • Sakaida, I.1    Matsumura, Y.2    Kubota, M.3    Kayano, K.4    Takenaka, K.5    Okita, K.6
  • 26
    • 0026775513 scopus 로고
    • Fat-storing cells as liver-specific pericytes: Spatial dynamics of agonist-stimulated intracellular calcium transients
    • Pinzani M, Failli P, Ruocco C, Casini A, Milani S, Baldi E, Giotti A, Gentilini P: Fat-storing cells as liver-specific pericytes: spatial dynamics of agonist-stimulated intracellular calcium transients. J Clin Invest 1992, 90:642-646
    • (1992) J Clin Invest , vol.90 , pp. 642-646
    • Pinzani, M.1    Failli, P.2    Ruocco, C.3    Casini, A.4    Milani, S.5    Baldi, E.6    Giotti, A.7    Gentilini, P.8
  • 29
    • 0018676475 scopus 로고
    • Native cross-links in collagen fibrils induce resistance to human synovial collagenase
    • Vater CA, Harris ED Jr, Siegel RC: Native cross-links in collagen fibrils induce resistance to human synovial collagenase. Biochem J 1979, 181:639-645
    • (1979) Biochem J , vol.181 , pp. 639-645
    • Vater, C.A.1    Harris Jr., E.D.2    Siegel, R.C.3
  • 30
    • 0013633737 scopus 로고    scopus 로고
    • Suppressive effects of estradiol on dimethyl-nitro-samine-induced fibrosis of the liver in normal and castrated rats of both sexes
    • Mizobuchi Y, Shimizu I, Yasuda M, Matunaga H, Ma Y, Escobar E, Shiba M, Ito S: Suppressive effects of estradiol on dimethyl-nitro-samine-induced fibrosis of the liver in normal and castrated rats of both sexes. Hepatology 1996, 24:462A
    • (1996) Hepatology , vol.24
    • Mizobuchi, Y.1    Shimizu, I.2    Yasuda, M.3    Matunaga, H.4    Ma, Y.5    Escobar, E.6    Shiba, M.7    Ito, S.8
  • 31
    • 0030587921 scopus 로고    scopus 로고
    • Effect of estradiol on chronic active hepatitis
    • Guattery JM, Faloon WW: Effect of estradiol on chronic active hepatitis. Ann Int Med 1996, 125:700
    • (1996) Ann Int Med , vol.125 , pp. 700
    • Guattery, J.M.1    Faloon, W.W.2
  • 32
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross R: The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993, 362:801-809
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 33
    • 0028214075 scopus 로고
    • Inhibition of PDGF receptor binding and PDGF-stimulated biological activity in vitro and of intimal lesion formation in vivo by 2-bromomethyl-5-chlorobenzene sulfonylphthalimide
    • Mullins DE, Hamud F, Reim R, Davis HR: Inhibition of PDGF receptor binding and PDGF-stimulated biological activity in vitro and of intimal lesion formation in vivo by 2-bromomethyl-5-chlorobenzene sulfonylphthalimide. Arterioscler Thromb 1994, 14:1047-1055
    • (1994) Arterioscler Thromb , vol.14 , pp. 1047-1055
    • Mullins, D.E.1    Hamud, F.2    Reim, R.3    Davis, H.R.4
  • 35
    • 0028915560 scopus 로고
    • Estrogen synthesis, estrogen metabolism, and functional estrogen receptors in rat arterial smooth muscle cells in culture
    • Bayard F, Clamens S, Meggetto F, Blaes N, Delsol G, Faye JC: Estrogen synthesis, estrogen metabolism, and functional estrogen receptors in rat arterial smooth muscle cells in culture. Endocrinology 1995, 136:1523-1529
    • (1995) Endocrinology , vol.136 , pp. 1523-1529
    • Bayard, F.1    Clamens, S.2    Meggetto, F.3    Blaes, N.4    Delsol, G.5    Faye, J.C.6
  • 38
    • 0027245407 scopus 로고
    • Sex difference in chronic hepatitis B virus infection: Studies of serum HBeAg and alanine aminotransferase levels in 10,431 asymptomatic Chinese HBsAg carriers
    • Chu CM, Sheen IS, Lin SM, Liaw YF: Sex difference in chronic hepatitis B virus infection: studies of serum HBeAg and alanine aminotransferase levels in 10,431 asymptomatic Chinese HBsAg carriers. Clin Infect Dis 1993, 16:709-713
    • (1993) Clin Infect Dis , vol.16 , pp. 709-713
    • Chu, C.M.1    Sheen, I.S.2    Lin, S.M.3    Liaw, Y.F.4
  • 39
    • 0025246255 scopus 로고
    • Hepatitis B-related sequelae: Prospective study in 1400 hepatitis B surface antigen-positive Alaska native carriers
    • McMahon BJ, Alberts SR, Wainwright RB, Bulkow L, Lanier AP: Hepatitis B-related sequelae: prospective study in 1400 hepatitis B surface antigen-positive Alaska native carriers. Arch Intern Med 1990, 150:1051-1054
    • (1990) Arch Intern Med , vol.150 , pp. 1051-1054
    • McMahon, B.J.1    Alberts, S.R.2    Wainwright, R.B.3    Bulkow, L.4    Lanier, A.P.5
  • 40
    • 0030933395 scopus 로고    scopus 로고
    • Natural history of liver fibrosis progression in patients with chronic hepatitis C
    • Poynard T, Bedossa P, Opolon P: Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 1997, 349: 825-832
    • (1997) Lancet , vol.349 , pp. 825-832
    • Poynard, T.1    Bedossa, P.2    Opolon, P.3
  • 41
    • 0020060218 scopus 로고
    • Hepatitis B virus as the etiologic agent in hepatocellular carcinoma: Epidemiologic considerations
    • Beasley RP: Hepatitis B virus as the etiologic agent in hepatocellular carcinoma: epidemiologic considerations. Hepatology 1982, 2:21S-26S
    • (1982) Hepatology , vol.2
    • Beasley, R.P.1
  • 42
    • 0027292382 scopus 로고
    • Hepatitis C-related hepatocellular carcinoma: Prevalence and significance
    • Resnick RH, Koff R: Hepatitis C-related hepatocellular carcinoma: prevalence and significance. Arch Int Med 1993, 153:1672-1677
    • (1993) Arch Int Med , vol.153 , pp. 1672-1677
    • Resnick, R.H.1    Koff, R.2
  • 45
    • 0028204118 scopus 로고
    • Inhibition of hepatic fibrogenesis: A review of pharmacologic candidates
    • Wu J, Danielsson A: Inhibition of hepatic fibrogenesis: a review of pharmacologic candidates. Scand J Gastroenterol 1994, 29:385-391
    • (1994) Scand J Gastroenterol , vol.29 , pp. 385-391
    • Wu, J.1    Danielsson, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.