-
1
-
-
0033782015
-
Dynamic interaction of GRP78/BiP and the ER stress transducers in the unfolded protein response
-
Bertolotti, A., Zhang, Y, Hendershot, L. M., Harding, H. P. and Ron, D. (2000) Dynamic interaction of GRP78/BiP and the ER stress transducers in the unfolded protein response. Nat Cell Biol, 2: 326-332.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
2
-
-
0032441479
-
Ubiquitin and the control of protein fate in the secretory and endocytic pathway
-
Bonifacino, J. S. and Weissman, A.M. (1998) Ubiquitin and the control of protein fate in the secretory and endocytic pathway. Annu Rev Cell Dev Biol, 14: 19-57.
-
(1998)
Annu Rev Cell Dev Biol
, vol.14
, pp. 19-57
-
-
Bonifacino, J.S.1
Weissman, A.M.2
-
3
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon, M., Zeng, H., Urano, F., Till, J.H., Hubbard, S.R., Harding, H.P., Clark, S.G. and Ron, D. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature, 415: 92-96.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
4
-
-
0029901711
-
GADD153/CHOP, a DNA damage-inducible protein, reduced CAAT/enhancer binding protein activities and increased apoptosis in 32D c13 myeloid cells
-
Friedman, A. D. (1996) GADD153/CHOP, a DNA damage-inducible protein, reduced CAAT/enhancer binding protein activities and increased apoptosis in 32D c13 myeloid cells. cancer Res, 56: 3250-3256.
-
(1996)
Cancer Res
, vol.56
, pp. 3250-3256
-
-
Friedman, A.D.1
-
5
-
-
0033590451
-
Translation and protein folding are coupled by an endoplasmic reticulum-resident kinase
-
Harding, H. P., Zhang, Y. and Ron, D. (1999) Translation and protein folding are coupled by an endoplasmic reticulum-resident kinase. Nature, 397: 271-274.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
6
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding, H.P., Novoa, I., Zhang, Y., Zeng, H., Wek, R., Schapira, M. and Ron, D. (2000) Regulated translation initiation con. trols stress-induced gene expression in mammalian cells. Mol Cell, 6: 1099-1108.
-
(2000)
Mol Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
7
-
-
0032693671
-
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
-
Haze, K., Yoshida, H., Yanagi, H., Yura, T. and Mori, K. (1999) Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol Biol Cell, 10: 3787-3799.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3787-3799
-
-
Haze, K.1
Yoshida, H.2
Yanagi, H.3
Yura, T.4
Mori, K.5
-
8
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
-
Imai, Y., Soda, M., Inoue, H., Hattori, N., Mizuno, Y. and Takahashi, R. (2001) An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell, 105: 891-902.
-
(2001)
Cell
, vol.105
, pp. 891-902
-
-
Imai, Y.1
Soda, M.2
Inoue, H.3
Hattori, N.4
Mizuno, Y.5
Takahashi, R.6
-
9
-
-
0033258544
-
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
-
Katayama, T., Imaizumi, K., Sato, N., Miyoshi, K., Kudo, T., Hitomi, J., Morihara, T., Yoneda, T., Gomi, F., Mori, Y., Nakano, Y., Takeda, J., Tsuda, T., Itoyama, Y., Murayama, O., Takashima, A., St George-Hyslop, P., Takeda, M. and Tohyama, M. (1999) Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat Cell Biol, 1: 479-485.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 479-485
-
-
Katayama, T.1
Imaizumi, K.2
Sato, N.3
Miyoshi, K.4
Kudo, T.5
Hitomi, J.6
Morihara, T.7
Yoneda, T.8
Gomi, F.9
Mori, Y.10
Nakano, Y.11
Takeda, J.12
Tsuda, T.13
Itoyama, Y.14
Murayama, O.15
Takashima, A.16
St. George-Hyslop, P.17
Takeda, M.18
Tohyama, M.19
-
10
-
-
0035900779
-
Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin 1 mutations
-
Katayama, T., Imaizumi, K., Honda, A., Yoneda, T., Kudo, T., Takeda, M., Mori, K., Rozmahel, R., Fraser, P., St George-Hyslop, P. and Tohyama, M. (2001) Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin 1 mutations. J Biol Chem, 276: 43446-43454.
-
(2001)
J Biol Chem
, vol.276
, pp. 43446-43454
-
-
Katayama, T.1
Imaizumi, K.2
Honda, A.3
Yoneda, T.4
Kudo, T.5
Takeda, M.6
Mori, K.7
Rozmahel, R.8
Fraser, P.9
St. George-Hyslop, P.10
Tohyama, M.11
-
11
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., Minoshima, S., Yokochi, M., Mizuno, Y. and Shimizu, N. (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature, 392: 605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
12
-
-
0025570285
-
Translational regulation of the immunoglobulin heavy-chain binding protein mRNA
-
Macejak, D. G. and Sarnow, P. (1990) Translational regulation of the immunoglobulin heavy-chain binding protein mRNA. Enzyme, 44: 310-319.
-
(1990)
Enzyme
, vol.44
, pp. 310-319
-
-
Macejak, D.G.1
Sarnow, P.2
-
13
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa, T. and Yuan, J. (2000) Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol, 150: 887-894.
-
(2000)
J Cell Biol
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
14
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa, T., Zhu, H., Morishima, N., Li, E., Xu, J., Yankner, B. A. and Yuan, J. (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature, 403: 98-103.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
15
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh, H., Matsuzawa, A., Tobiume, K., Saegusa, K., Takeda, K., Inoue, K., Hori, S., Kakizuka, A. and Ichijo, H. (2002) ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev, 16: 1345-1355.
-
(2002)
Genes Dev
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
Hori, S.7
Kakizuka, A.8
Ichijo, H.9
-
16
-
-
0034604350
-
Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes
-
Nohturfft, A., Yabe, D., Goldstein, J. L., Brown, M. S. and Espenshade, P. J. (2000) Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes. Cell, 102: 315-323.
-
(2000)
Cell
, vol.102
, pp. 315-323
-
-
Nohturfft, A.1
Yabe, D.2
Goldstein, J.L.3
Brown, M.S.4
Espenshade, P.J.5
-
17
-
-
0035947778
-
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α
-
Novoa, I., Zeng, H., Harding, H. P. and Ron, D. (2001) Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2α. J Cell Biol, 153: 1011-1022.
-
(2001)
J Cell Biol
, vol.153
, pp. 1011-1022
-
-
Novoa, I.1
Zeng, H.2
Harding, H.P.3
Ron, D.4
-
18
-
-
0036069980
-
ER stress regulation of ATF6 localization by dissociation of GRP78/BiP binding and unmasking of Golgi localization signals
-
Shen, J., Chen, X., Hendershot, L. and Prywes, R. (2002) ER stress regulation of ATF6 localization by dissociation of GRP78/BiP binding and unmasking of Golgi localization signals. Dev Cell, 3: 99-111.
-
(2002)
Dev Cell
, vol.3
, pp. 99-111
-
-
Shen, J.1
Chen, X.2
Hendershot, L.3
Prywes, R.4
-
19
-
-
0031755020
-
Identification and Characterization of pancreatic eukaryotic Initiation factor 2α-subunit kinase, PEK, involved in translational control
-
Shi, Y., Vattem, K. M., Sood, R., An, J., Liang, J., Stramm, L. and Wek, R. C. (1998) Identification and Characterization of pancreatic eukaryotic Initiation factor 2α-subunit kinase, PEK, involved in translational control. Mol Cell Biol, 18: 7499-7509.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 7499-7509
-
-
Shi, Y.1
Vattem, K.M.2
Sood, R.3
An, J.4
Liang, J.5
Stramm, L.6
Wek, R.C.7
-
20
-
-
0032101239
-
The unfolded protein response: An intracellular signalling pathway with many surprising features
-
Sidrauski, C., Chapman, R. and Walter, P. (1998) The unfolded protein response: An intracellular signalling pathway with many surprising features. Trends Cell Biol, 8: 245-249.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 245-249
-
-
Sidrauski, C.1
Chapman, R.2
Walter, P.3
-
21
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian-cells
-
Tirasophon, W., Welihinda, A. A. and Kaufman, R.J. (1998) A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian-cells. Genes Dev, 12: 1812-1824.
-
(1998)
Genes Dev
, vol.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
22
-
-
0032190546
-
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
-
Wang, X.-Z., Harding, H. P., Zhang, Y., Jolicoeur, E. M., Kuroda, M. and Ron, D. (1998) Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J, 17: 5708-5717.
-
(1998)
EMBO J
, vol.17
, pp. 5708-5717
-
-
Wang, X.-Z.1
Harding, H.P.2
Zhang, Y.3
Jolicoeur, E.M.4
Kuroda, M.5
Ron, D.6
-
23
-
-
0036386967
-
FAD-linked presenilin-1 mutants impede translation regulation under ER stress
-
Yasuda, Y., Kudo, T., Katayama, T., Imaizumi, K., Yatera, M., Okochi, M., Yamamori, H., Matsumoto, N., Kida, T., Fukumori, A., Okumura, M., Tohyama, M. and Takeda, M. (2002) FAD-linked presenilin-1 mutants impede translation regulation under ER stress. Biochem Biophys Res Commun, 296: 313-318.
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 313-318
-
-
Yasuda, Y.1
Kudo, T.2
Katayama, T.3
Imaizumi, K.4
Yatera, M.5
Okochi, M.6
Yamamori, H.7
Matsumoto, N.8
Kida, T.9
Fukumori, A.10
Okumura, M.11
Tohyama, M.12
Takeda, M.13
-
24
-
-
0034515724
-
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
-
Ye, J., Rawson, R. B., Komuro, R., Chen, X., Dave, U. P., Prywes, R., Brown, M. S. and Goldstein, J. L. (2000) ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell, 6: 1355-1364.
-
(2000)
Mol Cell
, vol.6
, pp. 1355-1364
-
-
Ye, J.1
Rawson, R.B.2
Komuro, R.3
Chen, X.4
Dave, U.P.5
Prywes, R.6
Brown, M.S.7
Goldstein, J.L.8
-
25
-
-
0035957929
-
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
-
Yoneda, T., Imaizumi, K., Oono, K., Yui, D., Gomi, F., Katayama, T. and Tohyama, M. (2001) Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J Biol Chem, 276: 13935-13940.
-
(2001)
J Biol Chem
, vol.276
, pp. 13935-13940
-
-
Yoneda, T.1
Imaizumi, K.2
Oono, K.3
Yui, D.4
Gomi, F.5
Katayama, T.6
Tohyama, M.7
-
26
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida, H., Matsui, T., Yamamoto, A., Okada, T. and Mori, K. (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell, 107: 881-891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
|