Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2

American Journal of Physiology - Renal Physiology

Volumn 281, Issue 4 50-4, 2001, Pages

  Ledoussal, Clara ^a   Lorenz, John N ^a   Nieman, Michelle L ^a   Soleimani, Manoocher ^a   Schultheis, Patrick J ^b   Shull, Gary E ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b NORTHERN KENTUCKY UNIVERSITY   (United States)

Author keywords

slc9a2; slc9a3; Sodium absorption; Sodium hydrogen exchanger

Indexed keywords

ELECTROLYTE; ISOPROTEIN; SODIUM;

ACID BASE BALANCE; ACIDOSIS; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; ELECTROLYTE BALANCE; FLUID BALANCE; GLOMERULUS FILTRATION RATE; HYPERKALEMIA; HYPOTENSION; HYPOVOLEMIC SHOCK; KIDNEY FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; SALT LOSING NEPHRITIS; SODIUM ABSORPTION; SODIUM EXCRETION; SODIUM RESTRICTION; SODIUM URINE LEVEL;

EID: 0034799335     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2001.281.4.f718     Document Type: Article

References (30)

1. Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb
2. Role of γENaC subunit in lung liquid clearance and electrolyte balance in newborn mice. Insights into perinatal adaptation and pseuhypoaldosteronism
3. + exchanger isoform of renal brush border
4. + transporter abundances in NHE3 and NCC null mice using targeted proteomics
5. + exchanger isoform NHE 2 in rat kidney
6. Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1
7. Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule
8. A mouse model for the renal salt-wasting syndrome pseuhypoaldosteronism
9. Micropuncture analysis of single-nephron function in NHE3-deficient mice
10. Renin release from isolated juxtaglomerular apparatus depends on macula densa chloride transport
11. + channel in mice: Hyperkalemia and neonatal death associated with pseudohypoaldosteronism phenotype
12. + deprivation in colonic H,K-ATPase-deficient mice
13. - reabsorption in renal collecting duct of NHE3-deficient mouse: A compensatory response
14. Molecular cloning of putative members of the Na/H exchanger gene family
15. Salt restriction induces pseudohypoaldosteronism type 1 in mice expressing low levels of the β-subunit of the amiloride-sensitive epithelial sodium channel
16. Function of the juxtaglomerular apparatus. Control of glomerular hemodynamics and renin secretion
17. Activation of tubuloglomerular feedback by chloride transport
18. + exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion
19. + exchanger
20. - cotransporter of the distal convoluted tubule
21. Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2
22. Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter
23. + exchanger isoforms NHE-2 and NHE-1 in inner medullary collecting duct cells. Expression, functional localization, and differential regulation
24. A novel splice-site mutation in the γ subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families
25. + exchanger isoform 2 (NHE2) is expressed in the apical membrane of the medullary thick ascending limb
26. Uncompensated polyuria in a mouse model of Bartter's syndrome
27. + exchanger isoform (NHE3)
28. + exchanger isoform (NHE-2)
29. Mechanism of proximal tubule bicarbonate absorption in NHE 3 null mice
30. Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger