Na+/H+ exchanger isoform 2 (NHE2) is expressed in the apical membrane of the medullary thick ascending limb

Journal of Membrane Biology

Volumn 160, Issue 1, 1997, Pages 85-90

  Sun, A M ^a   Liu, Y ^a   Dworkin, L D ^a   Tse, C M ^b   Donowitz, M ^b   Yip, K P ^a  

^a RHODE ISLAND HOSPITAL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; MESSENGER RNA;

ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HISTOCHEMISTRY; IMMUNOCHEMISTRY; IMMUNOFLUORESCENCE TEST; KIDNEY PROXIMAL TUBULE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTON SODIUM EXCHANGE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINO ACID SEQUENCE; ANIMALS; KIDNEY TUBULES, DISTAL; MALE; MICE; MOLECULAR SEQUENCE DATA; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SODIUM-HYDROGEN ANTIPORTER; SUBCELLULAR FRACTIONS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0030728255     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002329900297     Document Type: Article

References (27)

1. Alpern, R.J., Chambers, M. 1986. Cell pH in the rat proximal convoluted tubule. J. Clin. Invest. 78:502-510
2. Amemiya, M., Loffing, J., Lotscher, M., Kaissling, B., Apern, R.J., Moe, O.W. 1995. Expression of NHE3 in the apical membrane of rat renal proximal tubule and thick ascending. Kidney Int. 48:1206-1215
3. + exchanger isoforms and their regulation by thyroid hormone. Am. J. Physiol. 270:C585-C592
4. + exchanger isoform NHE1 in rabbit kidney. Am. J. Physiol. 263:F833-F840
5. + exchanger mRNAs in rat medullary thick ascending limb. Am. J. Physiol. 268:F1224-F1228
6. Brown, D., Lydon, M., Mclaughlin, A., Stuart-Tilley, R., Tyszkowski, R., Alper, S. 1996. Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS). Histochem. Cell. Biol. 105:261-267
7. + exchange in rat medullary thick ascending limb. Am. J. Physiol. 270:F691-F699
8. 3 exchange in the inner stripe of the rabbit outer medullary collecting tubule. J. Gen. Physiol. 95:347-367
9. Hoogerwerf, W.A., Tsao, S.C., Devuyst, O., Levine, S.A., Yun, C.H.C., Yip, J.W., Cohen, M.E., Wilson, P.D., Lazenby, A.J., Tse, C.M., Donowitz, M. 1996. NHE2 and NHE3 are human rabbit intestinal brush-border proteins. Am. J. Physiol. 270:G29-G41
10. + exchanges stably expressed in Chinese hamster ovary cells: ATP dependence, osmotic sensitivity and the role in cell proliferation. J. Biol. Chem. 269:23544-23552
11. Kikeri, D., Sun, A., Ziedel, M.L., Hebert, S.C. 1989. Cell membranes impermeable to NH3. Nature 339:478-480
12. + exchanger (NHE5/SLC9A5) to chromosome 16q22.1. Genomics 25:615-622
13. kB in the regulation of inducible nitric oxide synthase in an MTAL cell line. Am. J. Physiol. 269:F718-F729
14. Nagami, G.T. 1988. Luminal secretion of ammonia in the mouse proximal tubule perfused in vitro. J. Clin. Invest. 81:159-164
15. + exchange in renal proximal tubule cells. J. Biol. Chem. 269:27973-27978
16. + exchanger isoforms NHE2 and NHE1 on inner medullary collecting duct cells. J. Biol. Chem. 267:27973-27978
17. + exchanger in mouse medullary thick ascending limbs. Am. J. Physiol. 262:F241-F247
18. Sun, A.M., Nillni, E.A., Huo, T.L., Dworkin, L.D., Bookstein, C., Rao, M.C., Cheng, E.B., Lytton, J. 1994. Expression of NHE3 in the mouse medullary thick ascending limb (MTAL). J. Am Soc. Nephrol. 5:263 (Abstr.)
19. + exchanger isoform (NHE2). J. Biol. Chem. 268:11917-11924
20. + exchanger-2 (NHE2) is an O-linked but not a N-linked sialoglycoprotein. Biochemistry 33:12954-12961
21. Wang, Z., Orlowski, J., Shull, G.E. 1993. Primary structure and functional expression of a novel gastrointestinal isoform of rat Na/H exchanger. J. Biol. Chem. 268:11925-11928
22. + exchange in rat medullary thick ascending limb. J. Biol. Chem. 269:20250-20255
23. + exchanger by cAMP-dependent protein kinase. Am. J. Physiol. 258:F1254-F1258
24. + exchanger isoforms (NHE) NHE-2 and NHE-3 in rat proximal tubule during acute hypertension. J. Am. Soc. Nephrol. 6:318 (Abstr.)
25. 2+ exchanger by polymerase chain reaction. Am. J. Physiol. 263:F680-F685
26. + exchanger-deficient chinese hamster ovary cells. J. Biol. Chem. 268:25536-25541
27. + exchanger gene family: structure and function studies. Am. J. Physiol. 269:G1-G11