Saxitoxin is a gating modifier of hERG K+ channels

Journal of General Physiology

Volumn 121, Issue 6, 2003, Pages 583-598

  Wang, Jixin ^a   Salata, Joseph J ^a   Bennett, Paul B ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Antiarrhythmic; Ion channel; Kinetic model; Neurotoxin; Pro arrhythmia

Indexed keywords

POTASSIUM CHANNEL; SAXITOXIN; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DEPOLARIZATION; HEART ARRHYTHMIA; HEART REPOLARIZATION; HERG POTASIUM CHANNEL; HUMAN; HUMAN CELL; ION CONDUCTANCE; LONG QT SYNDROME; MEMBRANE POTENTIAL; POTASSIUM CURRENT;

CATION TRANSPORT PROTEINS; CELL LINE; DNA-BINDING PROTEINS; ETHER-A-GO-GO POTASSIUM CHANNELS; GENE EXPRESSION REGULATION; HEART; HUMANS; KINETICS; LONG QT SYNDROME; MEMBRANE POTENTIALS; MODELS, THEORETICAL; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; SAXITOXIN; TRANS-ACTIVATORS;

EID: 0038580639     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200308812     Document Type: Article

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