Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart

Physiological Genomics

Volumn 13, Issue , 2003, Pages 119-127

  Edwards, Michael G ^a   Sarkar, Deepayan ^b   Klopp, Roger ^a   Morrow, Jason D ^d   Weindruch, Richard ^a,c   Prolla, Tomas A ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b University of Wisconsin Madison   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d VANDERBILT UNIVERSITY   (United States)

Author keywords

Aging; Gene expression; Paraquat

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH FACTOR; MESSENGER RNA; PARAQUAT; ANTIOXIDANT; DUSP14 PROTEIN, MOUSE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN; PROTEIN TYROSINE PHOSPHATASE; SIGNAL PEPTIDE;

AGE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA MICROARRAY; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSCRIPTION; HEART; IMMEDIATE EARLY GENE; IMMUNE RESPONSE; INFLAMMATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; UNINDEXED SEQUENCE; AGING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; INTRAPERITONEAL DRUG ADMINISTRATION; LIPID PEROXIDATION; METABOLISM; METHODOLOGY; ONCOGENE; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN SYNTHESIS;

ANIMALIA;

AGING; ANIMALS; ANTIOXIDANTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, IMMEDIATE-EARLY; GENES, JUN; HEART; INJECTIONS, INTRAPERITONEAL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PARAQUAT; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN BIOSYNTHESIS; PROTEIN-TYROSINE-PHOSPHATASE; PROTEINS; TRANSCRIPTION, GENETIC;

EID: 0038519707     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00172.2002     Document Type: Article

References (53)

1. Ali M, Frei E, Straub J, Breuer A, and Wiessler M. Induction of metallothionein by zinc protects from daunorubicin toxicity in rats. Toxicology 179: 85, 2002.
2. Ali S, Diwakar G, and Pawa S. Paraquat induces different pulmonary biochemical responses in Wistar rats and Swiss mice. Chem Biol Interact 125: 79-91, 2000.
3. Aoki H, Kang PM, Hampe J, Yoshimura K, Noma T, Matsuzaki M, and Izumo S. Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes. J Biol Chem 277: 10244-10250, 2002.
4. Bandyopadhyay A, Shin DW, Ahn JO, and Kim DH. Calcineurin regulates ryanodine receptor/Ca(2+)-release channels in rat heart. Biochem J 352: 61-70, 2000.
5. Buck MJ, Squire TL, and Andrews MT. Coordinate expression of the PDK4 gene: a means of regulating fuel selection in a hibernating mammal. Physiol Genomics 8: 5-13, 2002. First published November 27, 2001; 10.1152/physiolgenomics.00076. 2001.
6. Cai L, Satoh M, Tohyama C, and Cherian MG. Metallothionein in radiation exposure: its induction and protective role. Toxicology 132: 85-98, 1999.
7. Cai Y, Zhang C, Nawa T, Aso T, Tanaka M, Oshiro S, Ichijo H, and Kitajima S. Homocysteine-responsive ATF3 gene expression in human vascular endothelial cells: activation of c-Jun NH(2)-terminal kinase and promoter response element. Blood 96: 2140-2148, 2000.
8. Campagne MV, Thibodeaux H, van Bruggen N, Cairns B, and Lowe DG. Increased binding activity at an antioxidant-responsive element in the metallothionein-1 promoter and rapid induction of metallothionein-1 and -2 in response to cerebral ischemia and reperfusion. J Neurosci 20: 5200-5207, 2000.
9. Cohen DM. Mitogen-activated protein kinase cascades and the signaling of hyperosmotic stress to immediate early genes. Comp Biochem Physiol A Physiol 117: 291-299, 1997.
10. Corasaniti MT, Strongoli MC, Rotiroti D, Bagetta G, and Nistico G. Paraquat: a useful tool for the in vivo study of mechanisms of neuronal cell death. Pharmacol Toxicol 83: 1-7, 1998.
11. Das DK, Maulik N, and Moraru II. Gene expression in acute myocardial stress. Induction by hypoxia, ischemia, reperfusion, hyperthermia and oxidative stress. J Mol Cell Cardiol 27: 181-193, 1995.
12. Dougherty CJ, Kubasiak LA, Prentice H, Andreka P, Bishopric NH, and Webster KA. Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress. Biochem J 362: 561-571, 2002.
13. Fabrizio P, Pozza F, Pletcher SD, Gendron CM, and Longo VD. Regulation of longevity and stress resistance by Sch9 in yeast. Science 292: 288-290, 2001.
14. Fisher HK, Clements JA, Tierney DF, and Wright RR. Pulmonary effects of paraquat in the first day after injection. Am J Physiol 228: 1217-1223, 1975.
15. Fornace AJ Jr, Alamo I Jr, and Hollander MC. DNA damage-inducible transcripts in mammalian cells. Proc Natl Acad Sci USA 85: 8800-8804, 1988.
16. Gerwins P, Blank JL, and Johnson GL. Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway J Biol Chem 272: 8288-8295, 1997.
17. Ghoshal R, Wang Y, Sheridan JF, and Jacob ST. Metallothionein induction in response to restraint stress. Transcriptional control, adaptation to stress, and role of glucocorticoid. J Biol Chem 273: 27904-27910, 1998.
18. Hall DM, Oberley TD, Moseley PM, Buettner GR, Oberley LW, Weindruch R, and Kregel KC. Caloric restriction improves thermotolerance and reduces hyperthermia-induced cellular damage in old rats. FASEB J 14: 78-86, 2000.
19. Harman D. The aging process. Proc Natl Acad Sci USA 78: 7124-7128, 1981.
20. Headrick J, Clarke K, and Willis RJ. Adenosine production and energy metabolism in ischaemic and metabolically stimulated rat heart. J Mol Cell Cardiol 21: 1089-1100, 1989.
21. Heydari AR, Wu B, Takahashi R, Strong R, and Richardson A. Expression of heat shock protein 70 is altered by age and diet at the level of transcription. Mol Cell Biol 13: 2909-2918, 1993.
22. Inuzuka H, Nanbu-Wakao R, Masuho Y, Muramatsu M, Tojo H, and Wakao H. Differential regulation of immediate early gene expression in preadipocyte cells through multiple signaling pathways. Biochem Biophys Res Commun 265: 664-668, 1999.
23. Lakatta EG. In: Handbook of the Biology of Aging (3rd ed.), edited by Schneider EL and Rowe JW. San Diego: Academic, 1990, p. 181-218.
24. Lee CK, Allison DB, Brand J, Weindruch R, and Prolla TA. Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts. Proc Natl Acad Sci USA 99: 14988-14993, 2002.
25. Lee CK, Klopp RG, Weindruch R, and Prolla TA. Gene expression profile of aging and its retardation by caloric restriction. Science 285: 1390-1393, 1999.
26. Lee CK, Weindruch R, and Prolla TA. Gene-expression profile of the ageing brain in mice. Nat Genet 25: 294-297, 2000.
27. Lin YJ, Seroude L, and Benzer S. Extended life-span and stress resistance in the Drosophila mutant methuselah. Science 282: 943-946, 1998.
28. Lloyd HG, Deussen A, Wuppermann H, and Schrader J. The transmethylation pathway as a source for adenosine in the isolated guinea-pig heart. Biochem J 252: 489-494, 1988.
29. Locke M and Tanguay RM. Diminished heat shock response in the aged myocardium. Cell Stress Chaperones 1: 251-260, 1996.
30. Mariani J, Ou R, Bailey M, Rowland M, Nagley P, Rosenfeldt F, and Pepe S. Tolerance to ischemia and hypoxia is reduced in aged human myocardium. J Thorac Cardiovasc Surg 120: 660-667, 2000.
31. Miller RA. In: Handbook of the Biology of Aging (4th ed.), edited by Schneider EL and Fowe JW. San Diego: Academic, 1996, p. 355-392.
32. Minamino T, Yujiri T, Papst PJ, Chan ED, Johnson GL, and Terada N. MEKK1 suppresses oxidative stress-induced apoptosis of embryonic stem cell-derived cardiac myocytes. Proc Natl Acad Sci USA 96: 15127-15132, 1999.
33. Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, and Olson EN. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93: 215-228, 1998.
34. Morrow JD and Roberts LJ II. Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress. Methods Enzymol 300: 3-12, 1999.
35. Murakami S and Johnson TE. Life extension and stress resistance in Caenorhabditis elegans modulated by the tkr-1 gene. Curr Biol 8: 1091-1094, 1998.
36. Noguchi N, Tanaka IE, Yamamoto H, and Misawa S. Initial accumulation of paraquat in the heart leading to acute death. Nippon Hoigaku Zasshi 44: 6-11, 1990.
37. Papaconstantinou J, Reisner PD, Liu L, and Kunninger D. Mechanisms of altered gene expression with aging. In: Handbook of the Biology of Aging (4th ed.), edited by Schneider EL and Rowe JW. San Diego: Academic, 1996, chapt. 8, p. 150-183.
38. Papathanasiou MA, Kerr NC, Robbins JH, McBride OW, Alamo I Jr, Barrett SF, Hickson ID, and Fornace AJ Jr. Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C. Mol Cell Biol 11: 1009-1016, 1991.
39. Parkinson C. The changing pattern of paraquat poisoning in man. Histopathology 4: 171-183, 1980.
40. Patil C and Walter P. Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals Curr Opin Cell Biol 13: 349-355, 2001.
41. Pugh TD, Klopp RG, and Weindruch R. Controlling caloric consumption: protocols for rodents and rhesus monkeys. Neurobiol Aging 20: 157-165, 1999.
42. Saito H and Papaconstantinou J. Age-associated differences in cardiovascular inflammatory gene induction during endotoxic stress. J Biol Chem 276: 29307-29312, 2001.
43. Shida M and Isoyama S. Effects of age on c-fos and c-myc gene expression in response to hemodynamic stress in isolated, perfused rat hearts. J Mol Cell Cardiol 25: 1025-1035, 1993.
44. Sohal RS, Agarwal S, Candas M, Forster MJ, and Lal H. Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice. Mech Ageing Dev 76: 215-224, 1994.
45. Sun D, Muthukumar AR, Lawrence RA, and Fernandes G. Effects of calorie restriction on polymicrobial peritonitis induced by cecum ligation and puncture in young C57BL/6 mice. Clin Diagn Lab Immunol 8: 1003-1011, 2001.
46. Takahashi T, Schunkert H, Isoyama S, Wei JY, Nadal-Ginard B, Grossman W, and Izumo S. Age-related differences in the expression of proto-oncogene and contractile protein genes in response to pressure overload in the rat myocardium. J Clin Invest 89: 939-946, 1992.
47. Takekawa M and Saito H. A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK. Cell 95: 521-530, 1998.
48. Tokunaga I, Kubo S, Mikasa H, Suzuki Y, and Morita K. Determination of 8-hydroxy-deoxyguanosine formation in rat organs: assessment of paraquat-evoked oxidative DNA damage. Biochem Mol Biol Int 43: 73-77, 1997.
49. Vander Heiden MG, Chandel NS, Li XX, Schumacker PT, Colombini M, and Thompson CB. Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival. Proc Natl Acad Sci USA 97: 4666-4671, 2000.
50. Venkatesan N. Pulmonary protective effects of curcumin against paraquat toxicity. Life Sci 66: PL21-PL28, 2000.
51. Wang XS, Diener K, Tan TH, and Yao Z. MAPKKK6, a novel mitogen-activated protein kinase kinase kinase, that associates with MAPKKK5. Biochem Biophys Res Commun 253: 33-37, 1998.
52. Waskiewicz AJ and Cooper JA. Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast. Curr Opin Cell Biol 7: 798-805, 1995.
53. Weindruch R and Walford RL. The Retardation of Aging and Disease by Dietary Restriction. Springfield, IL: Thomas, 1988.