메뉴 건너뛰기




Volumn 46, Issue 3, 2003, Pages 349-358

N-methylated β-carbolines protect PC12 cells from cytotoxic effect of MPP+ by attenuation of mitochondrial membrane permeability change

Author keywords

GSH depletion; Mitochondrial membrane permeability; MPP+; PC12 cells; Reactive oxygen species formation; Carbolines

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; ASCORBIC ACID; BETA CARBOLINE DERIVATIVE; CASPASE 3; CATALASE; CYTOCHROME C; DITHIOTHREITOL; GLUTATHIONE; HARMALINE; HARMALOL; HYDROGEN PEROXIDE; LINSIDOMINE; METHYL 4 PHENYLPYRIDINIUM; PYRIDINIUM DERIVATIVE; REACTIVE OXYGEN METABOLITE; RUTOSIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 0038510883     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(03)00097-X     Document Type: Article
Times cited : (32)

References (49)
  • 1
    • 0025688141 scopus 로고
    • Mitochondrial respiratory inhibition by N-methylated β-carboline derivatives structurally resembling N-methyl-4-phenylpyridine
    • Albores R., Neafsey E.J., Drucker G., Fields J.Z., Collins M.A. Mitochondrial respiratory inhibition by N-methylated β-carboline derivatives structurally resembling N-methyl-4-phenylpyridine. Proc. Natl. Acad. Sci. USA. 87:1990;9368-9372.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9368-9372
    • Albores, R.1    Neafsey, E.J.2    Drucker, G.3    Fields, J.Z.4    Collins, M.A.5
  • 2
    • 0032032270 scopus 로고    scopus 로고
    • Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockade of mitochondrial release of cytochrome c and activation of caspase-3
    • Amarante-Mendes G.P., Kim C.N., Liu L., Huang Y., Perkins C.L., Greeen D.R., Bhalla K. Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockade of mitochondrial release of cytochrome c and activation of caspase-3. Blood. 91:1998;1700-1705.
    • (1998) Blood , vol.91 , pp. 1700-1705
    • Amarante-Mendes, G.P.1    Kim, C.N.2    Liu, L.3    Huang, Y.4    Perkins, C.L.5    Greeen, D.R.6    Bhalla, K.7
  • 4
    • 0342378119 scopus 로고    scopus 로고
    • N-acetylcysteine protects against age-related increase in oxidized proteins in mouse synaptic mitochondria
    • Banaclocha M.M., Hernandez A.I., Martinez N., Ferrandiz M.L. N-acetylcysteine protects against age-related increase in oxidized proteins in mouse synaptic mitochondria. Brain Res. 762:1997;256-258.
    • (1997) Brain Res. , vol.762 , pp. 256-258
    • Banaclocha, M.M.1    Hernandez, A.I.2    Martinez, N.3    Ferrandiz, M.L.4
  • 5
    • 0030592172 scopus 로고    scopus 로고
    • The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death
    • Bernardi P. The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death. Biochim. Biophys. Acta. 1275:1996;5-9.
    • (1996) Biochim. Biophys. Acta , vol.1275 , pp. 5-9
    • Bernardi, P.1
  • 6
    • 0022365018 scopus 로고
    • Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: A longterm study
    • Birkmayer W., Knoll J., Riederer P., Youdim M.B., Hars V., Marton J. Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study. J. Neural Transm. 64:1985;113-127.
    • (1985) J. Neural Transm. , vol.64 , pp. 113-127
    • Birkmayer, W.1    Knoll, J.2    Riederer, P.3    Youdim, M.B.4    Hars, V.5    Marton, J.6
  • 7
    • 0032951125 scopus 로고    scopus 로고
    • + opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism
    • + opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism. Biochim. Biophys. Acta. 1453:1999;49-62.
    • (1999) Biochim. Biophys. Acta , vol.1453 , pp. 49-62
    • Cassarino, D.S.1    Parks, J.K.2    Parker W.D., Jr.3    Bennett J.P., Jr.4
  • 9
    • 0033805296 scopus 로고    scopus 로고
    • Triggering and modulation of apoptosis by oxidative stress
    • Chandra J., Samali A., Orrenius S. Triggering and modulation of apoptosis by oxidative stress. Free Radic. Biol. Med. 29:2000;323-333.
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 323-333
    • Chandra, J.1    Samali, A.2    Orrenius, S.3
  • 10
    • 0028176878 scopus 로고
    • + in PC12 cells: Insights into potential neurotoxicants in Parkinson's disease
    • + in PC12 cells: insights into potential neurotoxicants in Parkinson's disease. J. Neurochem. 62:1994;1503-1510.
    • (1994) J. Neurochem. , vol.62 , pp. 1503-1510
    • Cobuzzi R.J., Jr.1    Neafsey, E.J.2    Collins, M.A.3
  • 11
    • 0030984429 scopus 로고    scopus 로고
    • Involvement of a caspase-3-like cysteine protease in 1-methyl-4-phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons
    • Du Y., Dodel R.C., Bales K.R., Jemmerson R., Hamiton-Byrd E., Paul S.M. Involvement of a caspase-3-like cysteine protease in 1-methyl-4-phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons. J. Neurochem. 69:1997;1382-1388.
    • (1997) J. Neurochem. , vol.69 , pp. 1382-1388
    • Du, Y.1    Dodel, R.C.2    Bales, K.R.3    Jemmerson, R.4    Hamiton-Byrd, E.5    Paul, S.M.6
  • 13
    • 0035968068 scopus 로고    scopus 로고
    • + and MPTP in PC12 cells independent of reactive oxygen species formation
    • + and MPTP in PC12 cells independent of reactive oxygen species formation. Brain Res. 905:2001;199-206.
    • (2001) Brain Res. , vol.905 , pp. 199-206
    • Fonck, C.1    Baudry, M.2
  • 14
    • 0031773366 scopus 로고    scopus 로고
    • Catecholamines potentiate amyloid β-peptide neurotoxicity: Involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis
    • Fu W., Luo H., Parthasarathy S., Mattson M.P. Catecholamines potentiate amyloid β-peptide neurotoxicity: involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis. Neurobiol. Dis. 5:1998;229-243.
    • (1998) Neurobiol. Dis. , vol.5 , pp. 229-243
    • Fu, W.1    Luo, H.2    Parthasarathy, S.3    Mattson, M.P.4
  • 15
    • 0022580998 scopus 로고
    • MD240928 and harmaline: Opposite selectivity in antagonism of the inactivation of types A and B monoamine oxidase by pargyline in mice
    • Fuller R., Wong C.J., Hemrick-Luecke S.K. MD240928 and harmaline: opposite selectivity in antagonism of the inactivation of types A and B monoamine oxidase by pargyline in mice. Life Sci. 38:1986;409-412.
    • (1986) Life Sci. , vol.38 , pp. 409-412
    • Fuller, R.1    Wong, C.J.2    Hemrick-Luecke, S.K.3
  • 17
    • 0002143021 scopus 로고    scopus 로고
    • Detection of free radicals and other reactive species: Trapping and fingerprinting
    • B. Halliwell, & J.M.C. Gutteridge. New York: Oxford University Press
    • Halliwell B., Gutteridge J.M.C. Detection of free radicals and other reactive species: trapping and fingerprinting. Halliwell B., Gutteridge J.M.C. Free Radicals in Biology and Medicine. third ed. 1999;351-429 Oxford University Press, New York.
    • (1999) Free Radicals in Biology and Medicine third ed. , pp. 351-429
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 19
    • 0033984147 scopus 로고    scopus 로고
    • Role of the mitochondrial membrane permeability transition (MPT) in rotenone-induced apoptosis in liver cells
    • Isenberg J.S., Klaunig J.E. Role of the mitochondrial membrane permeability transition (MPT) in rotenone-induced apoptosis in liver cells. Toxicol. Sci. 53:2000;340-351.
    • (2000) Toxicol. Sci. , vol.53 , pp. 340-351
    • Isenberg, J.S.1    Klaunig, J.E.2
  • 20
    • 0033042075 scopus 로고    scopus 로고
    • Dopamine and glutamate neurotoxicity in cultured chick telencephali cells: Effects of NMDA antagonists, antioxidants and MAO inhibitors
    • Jacobsson S.O., Fowler C.J. Dopamine and glutamate neurotoxicity in cultured chick telencephali cells: effects of NMDA antagonists, antioxidants and MAO inhibitors. Neurochem. Int. 34:1999;49-62.
    • (1999) Neurochem. Int. , vol.34 , pp. 49-62
    • Jacobsson, S.O.1    Fowler, C.J.2
  • 21
    • 0030775042 scopus 로고    scopus 로고
    • Decreased glutathione results in calcium-mediated cell death in PC12
    • Jurma O.P., Hom D.G., Andersen J.K. Decreased glutathione results in calcium-mediated cell death in PC12. Free Radic. Biol. Med. 23:1997;1055-1066.
    • (1997) Free Radic. Biol. Med. , vol.23 , pp. 1055-1066
    • Jurma, O.P.1    Hom, D.G.2    Andersen, J.K.3
  • 23
    • 0034969732 scopus 로고    scopus 로고
    • Protective effect of harmaline and harmalol against dopamine- and 6-hydroxydopamine-induced oxidative damage of brain mitochondria and synaptosomes, and viability loss of PC12 cells
    • Kim D.H., Jang Y.Y., Han E.S., Lee C.S. Protective effect of harmaline and harmalol against dopamine- and 6-hydroxydopamine-induced oxidative damage of brain mitochondria and synaptosomes, and viability loss of PC12 cells. Eur. J. Neurosci. 13:2001;1861-1872.
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 1861-1872
    • Kim, D.H.1    Jang, Y.Y.2    Han, E.S.3    Lee, C.S.4
  • 25
    • 0343081001 scopus 로고    scopus 로고
    • Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 Cells
    • Lee C.S., Han E.S., Jang Y.Y., Han J.H., Ha H.W., Kim D.E. Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 Cells. J. Neurochem. 75:2000;521-531.
    • (2000) J. Neurochem. , vol.75 , pp. 521-531
    • Lee, C.S.1    Han, E.S.2    Jang, Y.Y.3    Han, J.H.4    Ha, H.W.5    Kim, D.E.6
  • 27
    • 0034022635 scopus 로고    scopus 로고
    • Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occurring during 7-ketocholesterol-induced apoptosis
    • Lizard G., Miguet C., Bessede G., Monier S., Gueldry S., Neel D., Gambert P. Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occurring during 7-ketocholesterol-induced apoptosis. Free Radic. Biol. Med. 28:2000;743-753.
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 743-753
    • Lizard, G.1    Miguet, C.2    Bessede, G.3    Monier, S.4    Gueldry, S.5    Neel, D.6    Gambert, P.7
  • 28
    • 0034624017 scopus 로고    scopus 로고
    • The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity
    • Lotharius J., O'Malley K.L. The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity. J. Biol. Chem. 275:2000;38581-38588.
    • (2000) J. Biol. Chem. , vol.275 , pp. 38581-38588
    • Lotharius, J.1    O'Malley, K.L.2
  • 29
    • 0033557640 scopus 로고    scopus 로고
    • Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons
    • Lotharius J., Dugan L.L., O'Malley K.L. Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons. J. Neurosci. 19:1999;1284-1293.
    • (1999) J. Neurosci. , vol.19 , pp. 1284-1293
    • Lotharius, J.1    Dugan, L.L.2    O'Malley, K.L.3
  • 30
    • 0029844831 scopus 로고    scopus 로고
    • The role of monoamine metabolism in oxidative glutamate toxicity
    • Maher P., Davis J.B. The role of monoamine metabolism in oxidative glutamate toxicity. J. Neurosci. 16:1996;6394-6401.
    • (1996) J. Neurosci. , vol.16 , pp. 6394-6401
    • Maher, P.1    Davis, J.B.2
  • 31
    • 0027252719 scopus 로고
    • Potential bioactivated neurotoxicants, N-methylated β-carbolinium ions, are present in human brain
    • Matsubara K., Collins M.A., Akane A., Ikebuchi J., Neafsey E.J., Kagawa M., Shiono H. Potential bioactivated neurotoxicants, N-methylated β-carbolinium ions, are present in human brain. Brain Res. 610:1993;90-96.
    • (1993) Brain Res. , vol.610 , pp. 90-96
    • Matsubara, K.1    Collins, M.A.2    Akane, A.3    Ikebuchi, J.4    Neafsey, E.J.5    Kagawa, M.6    Shiono, H.7
  • 33
    • 0031952527 scopus 로고    scopus 로고
    • Endogenously occurring β-carboline induces parkinsonism in nonprimate animals: A possible causative protoxin in idiopathic Parkinson's disease
    • Matsubara K., Gonda T., Sawada H., Uezono T., Kobayashi Y., Kawamura T., Ohtaki K., Kimura K., Akaike A. Endogenously occurring β-carboline induces parkinsonism in nonprimate animals: a possible causative protoxin in idiopathic Parkinson's disease. J. Neurochem. 70:1998;727-735.
    • (1998) J. Neurochem. , vol.70 , pp. 727-735
    • Matsubara, K.1    Gonda, T.2    Sawada, H.3    Uezono, T.4    Kobayashi, Y.5    Kawamura, T.6    Ohtaki, K.7    Kimura, K.8    Akaike, A.9
  • 34
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods. 65:1983;55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 35
    • 0036053197 scopus 로고    scopus 로고
    • Dopamine efflux by MPTP and hydroxyl radical generation
    • Obata T. Dopamine efflux by MPTP and hydroxyl radical generation. J. Neural Transm. 109:2002;1159-1180.
    • (2002) J. Neural Transm. , vol.109 , pp. 1159-1180
    • Obata, T.1
  • 36
  • 38
    • 0027171217 scopus 로고
    • Degeneration of Purkinje cells in parasagittal zones of the cerebellar vermis after treatment with ibogaine or harmaline
    • O'Hearn E., Molliver M.E. Degeneration of Purkinje cells in parasagittal zones of the cerebellar vermis after treatment with ibogaine or harmaline. Neuroscience. 55:1993;303-310.
    • (1993) Neuroscience , vol.55 , pp. 303-310
    • O'Hearn, E.1    Molliver, M.E.2
  • 40
  • 41
    • 0029037495 scopus 로고
    • The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide
    • Pryor W.A., Squadrito G.L. The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am. J. Physiol. 268:1995;L699-L722.
    • (1995) Am. J. Physiol. , vol.268
    • Pryor, W.A.1    Squadrito, G.L.2
  • 43
    • 0031589740 scopus 로고    scopus 로고
    • Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors
    • Seaton T.A., Cooper J.M., Schapira A.H. Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors. Brain Res. 777:1997;110-118.
    • (1997) Brain Res. , vol.777 , pp. 110-118
    • Seaton, T.A.1    Cooper, J.M.2    Schapira, A.H.3
  • 44
    • 0032526940 scopus 로고    scopus 로고
    • The regulation of reactive oxygen species production during programmed cell death
    • Tan S., Sagara Y., Liu Y., Maher P., Schubert D. The regulation of reactive oxygen species production during programmed cell death. J. Cell Biol. 141:1998;1423-1432.
    • (1998) J. Cell Biol. , vol.141 , pp. 1423-1432
    • Tan, S.1    Sagara, Y.2    Liu, Y.3    Maher, P.4    Schubert, D.5
  • 45
    • 0029731378 scopus 로고    scopus 로고
    • Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration
    • Tatton W.G., Chalmers-Redman R.M. Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration. Neurology. 47:1996;S171-S183.
    • (1996) Neurology , vol.47
    • Tatton, W.G.1    Chalmers-Redman, R.M.2
  • 46
    • 0036229947 scopus 로고    scopus 로고
    • Propargylamines induce antiapoptotic new protein synthesis in serum-and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells
    • Tatton W.G., Chalmers-Redman R.M.E., Ju W.J.H., Mammen M., Carlile G.W., Pong A.W., Tatton N.A. Propargylamines induce antiapoptotic new protein synthesis in serum-and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells. J. Pharmacol. Exp. Ther. 301:2002;753-764.
    • (2002) J. Pharmacol. Exp. Ther. , vol.301 , pp. 753-764
    • Tatton, W.G.1    Chalmers-Redman, R.M.E.2    Ju, W.J.H.3    Mammen, M.4    Carlile, G.W.5    Pong, A.W.6    Tatton, N.A.7
  • 47
    • 0031013986 scopus 로고    scopus 로고
    • Increase in gamma-glutamyltransferase by glutathione depletion in rat type II pneumocytes
    • van Klaveren R.J., Hoet P.H., Pype J.L., Demedts M., Nemery B. Increase in gamma-glutamyltransferase by glutathione depletion in rat type II pneumocytes. Free Radic. Biol. Med. 22:1997;525-534.
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 525-534
    • Van Klaveren, R.J.1    Hoet, P.H.2    Pype, J.L.3    Demedts, M.4    Nemery, B.5
  • 49
    • 0031025395 scopus 로고    scopus 로고
    • Energy stress-induced dopamine loss in glutathione peroxidase-overexpressing transgenic mice and in glutathione-depleted mesencephalic cultures
    • Zeevalk G.D., Bernard L.P., Albers D.S., Mirochnitchenko O., Nicklas W.J., Sonsalla P.K. Energy stress-induced dopamine loss in glutathione peroxidase-overexpressing transgenic mice and in glutathione-depleted mesencephalic cultures. J. Neurochem. 68:1997;426-429.
    • (1997) J. Neurochem. , vol.68 , pp. 426-429
    • Zeevalk, G.D.1    Bernard, L.P.2    Albers, D.S.3    Mirochnitchenko, O.4    Nicklas, W.J.5    Sonsalla, P.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.