SCOPUS 정보 검색 플랫폼

Journal of Molecular Structure: THEOCHEM

Volumn 626, Issue 1-3, 2003, Pages 209-216

An approximation to the mechanism of inhibition of cystein proteases: Nucleophilic sulphur addition to Michael acceptors type compounds

(3) Kunakbaeva, Z a Carrasco, R a Rozas, I b

a Center of Pharmaceutical Chemistry Cuba (Cuba)

b TRINITY COLLEGE DUBLIN (Ireland)

Author keywords

Cysteine proteases; Michael type acceptors; PM3

Indexed keywords

3 MERCAPTOPROPIONIC ACID; ACETYLCYSTEINE; ACRYLAMIDE; ACRYLIC ACID METHYL ESTER; ACRYLONITRILE; CYSTEINE; CYSTEINE PROTEINASE; HOMOCYSTEINE; THIOGLYCOLIC ACID;

ARTICLE; CALCULATION; CHEMICAL BOND; CORRELATION ANALYSIS; ENERGY; ENZYME ACTIVE SITE; ENZYME INHIBITION; MICHAEL ADDITION; MODEL; QUANTUM CHEMISTRY; REACTION ANALYSIS; REACTION TIME; STRUCTURE ANALYSIS;

EID: 0038476391 PISSN: 01661280 EISSN: None Source Type: Journal
DOI: 10.1016/S0166-1280(03)00086-1 Document Type: Article

Times cited : (18)

References (34)

1
- 0037913515
- J.S. Bond, P.E. Butler, Annu. Rev. Biochem. 333 (1987) 56.
- (1987) Annu. Rev. Biochem. , vol.333 , pp. 56
- Bond, J.S.¹ Butler, P.E.²

2
- 0037913508
- D.W. Nicholson, A. Ali, N.A. Thornberry, J.P. Vaillan-court, C.K. Ding, M. Gallant, Y. Gareau, P.R. Griffin, M. Labeille, Y.A. Lazebnik, N.A. Munday, S.M. Raju, M.E. Smulson, T.-T. Yamin, V.L. Lu, D.K. Miller, Nature 37 (1995) 376.
- (1995) Nature , vol.37 , pp. 376
- Nicholson, D.W.¹ Ali, A.² Thornberry, N.A.³ Vaillan-court, J.P.⁴ Ding, C.K.⁵ Gallant, M.⁶ Gareau, Y.⁷ Griffin, P.R.⁸ Labeille, M.⁹ Lazebnik, Y.A.¹⁰ Munday, N.A.¹¹ Raju, S.M.¹² Smulson, M.E.¹³ Yamin, T.-T.¹⁴ Lu, V.L.¹⁵ Miller, D.K.¹⁶

3
- 0005373489
- N.A. Thornberry, D.K. Miller, D.W. Nicholson, Perspect. Drug. Discov. Des. 2 (1994) 389.
- (1994) Perspect. Drug. Discov. Des. , vol.2 , pp. 389
- Thornberry, N.A.¹ Miller, D.K.² Nicholson, D.W.³

4
- 0001783129
- P.S. Anderson, G.L. Kenyon, G.R. Marshall (Eds.), ESCOM Science, Leiden
- C.D. Robertson, G.H. Coombs, M.J. Noth, J.C. Mottram, in: P.S. Anderson, G.L. Kenyon, G.R. Marshall (Eds.), Perspect. Drug Discov. Des., 6, ESCOM Science, Leiden, 1996, p. 99.
- (1996) Perspect. Drug Discov. Des. , vol.6 , pp. 99
- Robertson, C.D.¹ Coombs, G.H.² Noth, M.J.³ Mottram, J.C.⁴

5
- 0038589533
- P.J. Rosenthal, J. Med. Chem. 40 (1997) 2726.
- (1997) J. Med. Chem. , vol.40 , pp. 2726
- Rosenthal, P.J.¹

6
- 0034717913
- D.R. Ifa, C.R. Rodrigues, R.B. de Alencastro, C.A.M. Fraga, E.J. Barreiro, J. Mol. Struct. (Theochem) 505 (2000) 11.
- (2000) J. Mol. Struct. (Theochem) , vol.505 , pp. 11
- Ifa, D.R.¹ Rodrigues, C.R.² De Alencastro, R.B.³ Fraga, C.A.M.⁴ Barreiro, E.J.⁵

7
- 84962407693
- M. Štrajbl, J. Florián, A. Warshel, J. Phys. Chem. B 105 (2001) 4471.
- (2001) J. Phys. Chem. B , vol.105 , pp. 4471
- Štrajbl, M.¹ Florián, J.² Warshel, A.³

8
- 0343433408
- H.-H. Otto, T. Schirmeister, Chem. Rev. 97 (1997) 133.
- (1997) Chem. Rev. , vol.97 , pp. 133
- Otto, H.-H.¹ Schirmeister, T.²

9
- 0037203970
- Among others: (a) L. Huang, A. Lee, J.A. Ellman, J. Med. Chem. 45 (2002) 676.
- (2002) J. Med. Chem. , vol.45 , pp. 676
- Huang, L.¹ Lee, A.² Ellman, J.A.³

10
- 0035891721
- (b) A. Lee, J.A. Ellman, Org. Lett. 3 (2001) 3707.
- (2001) Org. Lett. , vol.3 , pp. 3707
- Lee, A.¹ Ellman, J.A.²

11
- 0035458539
- (c) A. Graven, P.M. St Hilaire, S.J. Sanderson, J.C. Mottram, G.H. Coombs, M. Medal, J. Comb. Chem. 3 (2001) 441.
- (2001) J. Comb. Chem. , vol.3 , pp. 441
- Graven, A.¹ St. Hilaire, P.M.² Sanderson, S.J.³ Mottram, J.C.⁴ Coombs, G.H.⁵ Medal, M.⁶

12
- 0033598321
- (d) P. Abato, J.L. Conroy, C.T. Seto, J. Med. Chem. 42 (1999) 4001.
- (1999) J. Med. Chem. , vol.42 , pp. 4001
- Abato, P.¹ Conroy, J.L.² Seto, C.T.³

13
- 24844461991
- R.P. Hanzlik, S.P. Jacober, J. Zygmunt, Biochim. Biophys. Acta 33 (1991) 1073.
- (1991) Biochim. Biophys. Acta , vol.33 , pp. 1073
- Hanzlik, R.P.¹ Jacober, S.P.² Zygmunt, J.³

14
- 0029815897
- Z. Li, A.-C. Ortega-Vilain, G.S. Patil, D.-L. Chu, J.E. Foreman, D.D. Eveleth, J.C. Powers, J. Med. Chem. 39 (1996) 4089.
- (1996) J. Med. Chem. , vol.39 , pp. 4089
- Li, Z.¹ Ortega-Vilain, A.-C.² Patil, G.S.³ Chu, D.-L.⁴ Foreman, J.E.⁵ Eveleth, D.D.⁶ Powers, J.C.⁷

15
- 0032557226
- Z. Guo, J. Ramirez, J. Li, P.G. Wang, J. Am. Chem. Soc. 120 (1998) 3726.
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 3726
- Guo, Z.¹ Ramirez, J.² Li, J.³ Wang, P.G.⁴

16
- 0030716360
- (a) D.S. Yamashita, W.W. Smith, B. Zhao, C.A. Janson, T.A. Tomaszek, M.J. Bossard, M.A. Levy, H.-J. Oh, T.J. Carr, N.K. Thomson, C.F. James, S.A. Carr, M. McQueney, K.J. D'Alessio, B.Y. Amegadzie, C.R. Hanning, S. Abdel-Meguid, R.L. DesJarlais, J.G. Gleason, D.F. Veber, J. Am. Chem. Soc. 119 (1997) 11351.
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 11351
- Yamashita, D.S.¹ Smith, W.W.² Zhao, B.³ Janson, C.A.⁴ Tomaszek, T.A.⁵ Bossard, M.J.⁶ Levy, M.A.⁷ Oh, H.-J.⁸ Carr, T.J.⁹ Thomson, N.K.¹⁰ James, C.F.¹¹ Carr, S.A.¹² McQueney, M.¹³ D'Alessio, K.J.¹⁴ Amegadzie, B.Y.¹⁵ Hanning, C.R.¹⁶ Abdel-Meguid, S.¹⁷ DesJarlais, R.L.¹⁸ Gleason, J.G.¹⁹ Veber, D.F.²⁰ more..

17
- 0032505149
- (b) R.W. Marquis, D.S. Yamashita, Y. Ru, S.M. LoCastro, H.-J. Oh, K.F. Erhard, R.L. DesJarlais, M.S. Head, W.W. Smith, B. Zhao, C.A. Janson, S.S. Abdel-Meguid, T.A. Tomaszek, M.A. Levy, D.F. Veber, J. Med. Chem. 41 (1998) 3563.
- (1998) J. Med. Chem. , vol.41 , pp. 3563
- Marquis, R.W.¹ Yamashita, D.S.² Ru, Y.³ LoCastro, S.M.⁴ Oh, H.-J.⁵ Erhard, K.F.⁶ DesJarlais, R.L.⁷ Head, M.S.⁸ Smith, W.W.⁹ Zhao, B.¹⁰ Janson, C.A.¹¹ Abdel-Meguid, S.S.¹² Tomaszek, T.A.¹³ Levy, M.A.¹⁴ Veber, D.F.¹⁵

18
- 0035282807
- R.W. Marquis, Y. Ru, J. Zeng, R.E.L. Trout, S.M. LoCastro, A.D. Gribble, J. Witherington, A.E. Fenwick, B. Garnier, T. Tomasezeck, D. Tew, M.E. Hemling, C.J. Quinn, W.W. Smith, B. Zhao, M.S. McQueney, C.A. Janson, K. D'Alessio, D.F. Veber, J. Med. Chem. 44 (2001) 725.
- (2001) J. Med. Chem. , vol.44 , pp. 725
- Marquis, R.W.¹ Ru, Y.² Zeng, J.³ Trout, R.E.L.⁴ LoCastro, S.M.⁵ Gribble, A.D.⁶ Witherington, J.⁷ Fenwick, A.E.⁸ Garnier, B.⁹ Tomasezeck, T.¹⁰ Tew, D.¹¹ Hemling, M.E.¹² Quinn, C.J.¹³ Smith, W.W.¹⁴ Zhao, B.¹⁵ McQueney, M.S.¹⁶ Janson, C.A.¹⁷ D'Alessio, K.¹⁸ Veber, D.F.¹⁹

19
- 0032478745
- J.L. Conroy, C.T. Seto, J. Org. Chem. 63 (1998) 2367.
- (1998) J. Org. Chem. , vol.63 , pp. 2367
- Conroy, J.L.¹ Seto, C.T.²

20
- 0021260942
- (a) R.P. Hanzlik, S.A. Thomson, J. Med. Chem. 27 (1984) 711.
- (1984) J. Med. Chem. , vol.27 , pp. 711
- Hanzlik, R.P.¹ Thomson, S.A.²

21
- 0026517333
- (b) S. Liu, R.P. Hanzlik, J. Med. Chem. 35 (1992) 1067.
- (1992) J. Med. Chem. , vol.35 , pp. 1067
- Liu, S.¹ Hanzlik, R.P.²

22
- 0029099619
- (c) J.T. Palmer, D. Raznik, J.L. Klaus, D. Brömme, J. Med. Chem. 38 (1995) 3193.
- (1995) J. Med. Chem. , vol.38 , pp. 3193
- Palmer, J.T.¹ Raznik, D.² Klaus, J.L.³ Brömme, D.⁴

23
- 24844472734
- (d) D. Brömme, J.L. Klaus, K. Okamoto, D. Raznik, J.T. Palmer, Biochem. J. 85 (1996) 315.
- (1996) Biochem. J. , vol.85 , pp. 315
- Brömme, D.¹ Klaus, J.L.² Okamoto, K.³ Raznik, D.⁴ Palmer, J.T.⁵

24
- 0033602268
- (e) T. Schirmeister, J. Med. Chem. 42 (1999) 560.
- (1999) J. Med. Chem. , vol.42 , pp. 560
- Schirmeister, T.¹

25
- 0035830510
- M. Demarcus, M.L. Ganadu, G.M. Mura, A. Porcheddu, L. Quaranta, G. Reginato, M. Taddei, J. Org. Chem. 66 (2001) 697.
- (2001) J. Org. Chem. , vol.66 , pp. 697
- Demarcus, M.¹ Ganadu, M.L.² Mura, G.M.³ Porcheddu, A.⁴ Quaranta, L.⁵ Reginato, G.⁶ Taddei, M.⁷

26
- 0034715481
- Y. Nakao, M. Fujita, K. Warabi, S. Matsunaga, N. Fusetani, J. Am. Chem. Soc. 122 (2000) 10462.
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 10462
- Nakao, Y.¹ Fujita, M.² Warabi, K.³ Matsunaga, S.⁴ Fusetani, N.⁵

27
- 0031744850
- N. Fusetani, J. Nat. Prod. 61 (1998) 671.
- (1998) J. Nat. Prod. , vol.61 , pp. 671
- Fusetani, N.¹

28
- 0000159773
- R. Adams, A.H. Blatt, V. Boekelheide, A.C. Cope, D.Y. Curtin, F.C. McGrew, C. Niemann (Eds.), Wiley, New York
- E.D. Bergman, D. Ginsburg, R. Pappo, in: R. Adams, A.H. Blatt, V. Boekelheide, A.C. Cope, D.Y. Curtin, F.C. McGrew, C. Niemann (Eds.), Organic Reactions, vol. 10, Wiley, 1959, pp. 179-555, New York.
- (1959) Organic Reactions , vol.10 , pp. 179-555
- Bergman, E.D.¹ Ginsburg, D.² Pappo, R.³

29
- 0029099619
- J.T. Palmer, D. Rasnik, J.L. Klaus, D. Brömme, J. Med. Chem. 38 (1995) 3193.
- (1995) J. Med. Chem. , vol.38 , pp. 3193
- Palmer, J.T.¹ Rasnik, D.² Klaus, J.L.³ Brömme, D.⁴

30
- 0000189906
- M. Friedman, J.F. Cavins, J.S. Wall, J. Am. Chem. Soc. 87 (1965) 3672.
- (1965) J. Am. Chem. Soc. , vol.87 , pp. 3672
- Friedman, M.¹ Cavins, J.F.² Wall, J.S.³

31
- 0348209279
- Hypercube, Inc
- HyperChem™ Release 5.02 for Windows 95/NT Molecular Model System. Hypercube, Inc., 1997.
- (1997) HyperChem™ Release 5.02 for Windows 95/NT Molecular Model System

32
- 0038251036
- J.J.P. Stewart, MOPAC 6.0. Manual QCPE #581.
- MOPAC 6.0. Manual QCPE #581
- Stewart, J.J.P.¹

33
- 0025390935
- J.J.P. Stewart, J. Comp. Aid. Mol. Des. 4 (1990) 1.
- (1990) J. Comp. Aid. Mol. Des. , vol.4 , pp. 1
- Stewart, J.J.P.¹

34
- 85031175463
- March 1997, Windows 95 and NT environments. Universidad de La Habana, Cuba
- MOPAC v.6 for 3/486/Pentium PC's. Release 1.02, March 1997, Windows 95 and NT environments. Universidad de La Habana, Cuba, 1994-1997.
- (1994) MOPAC V.6 for 3/486/Pentium PC's. Release 1.02

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.