Novel peptidyl α-keto amide inhibitors of calpains and other cysteine proteases

Journal of Medicinal Chemistry

Volumn 39, Issue 20, 1996, Pages 4089-4098

  Li, Zhaozhao ^a   Ortega Vilain, Anne Cécile ^a   Patil, Girish S ^a   Chu, Der Lun ^a   Foreman, J E ^b   Eveleth, David D ^b   Powers, James C ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b Cortex Pharmaceuticals Inc ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; CATHEPSIN B; CYSTEINE PROTEINASE INHIBITOR; DIPEPTIDE; SPECTRIN;

ANIMAL CELL; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG PENETRATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; NEUROPROTECTION; NONHUMAN; RAT; THROMBOCYTE MEMBRANE;

ANIMALS; BLOOD PLATELETS; CALPAIN; CATHEPSIN B; CELL MEMBRANE PERMEABILITY; CYSTEINE PROTEINASE INHIBITORS; MOLECULAR STRUCTURE; OLIGOPEPTIDES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029815897     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950541c     Document Type: Article

References (27)

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