Demonstration by 13C NMR studies that tetrahydropyranone-based inhibitors bind to cysteine proteases by reversible formation of a hemithioketal adduct

Journal of Organic Chemistry

Volumn 63, Issue 7, 1998, Pages 2367-2370

  Conroy, J L ^a   Seto, C T ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; TETRAHYDROPYRAN DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DIASTEREOISOMER; ENZYME INHIBITOR INTERACTION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION;

EID: 0032478745     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo971834b     Document Type: Article

References (0)