Vα24+ natural killer T cells are markedly decreased in atopic dermatitis patients

Human Immunology

Volumn 64, Issue 6, 2003, Pages 586-592

  Takahashi, Tsuyoshi ^a   Nakamura, Koichiro ^a   Chiba, Shigeru ^a   Kanda, Yoshinobu ^a   Tamaki, Kunihiko ^a   Hirai, Hisamaru ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Atopic dermatitis; Th1 Th2; V 24+ NKT

Indexed keywords

CD4 ANTIGEN; CYTOKINE; GALACTOSYLCERAMIDE; GAMMA INTERFERON; INTERLEUKIN 4;

ADULT; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HUMAN; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; NATURAL KILLER CELL; PRIORITY JOURNAL; SKIN INFLAMMATION; T LYMPHOCYTE; TH1 CELL; TH2 CELL; VALPHA24 NATURAL KILLER T CELL;

EID: 0038458960     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(03)00066-1     Document Type: Article

References (35)

1. Leung DYM: Pathogenesis of atopic dermatitis. J Allergy Clin Immunol 104:S99, 1999.
2. Ono SJ: Molecular genetics of allergic diseases. Annu Rev Immunol 18:347, 2000.
3. -T cells. J Exp Med 186:109, 1997.
4. Brossay L, Chioda M, Burdin N, Koezuka Y, Casorati G, Dellabona P, Kronenberg M: CD1d-mediated recognition of a α-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J Exp Med 188:1521, 1998.
5. Spada M, Koezuka Y, Porcelli SA: CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells. J Exp Med 188:1529, 1998.
6. Nieda M, Nicol A, Koezuka Y, Kikuchi A, Takahashi T, Nakamura H, Furukawa H, Yabe T, Ishikawa Y, Tadokoro K, Juji T: Activation of human Vα24NKT cells by α-glycosylceramide in a CD1d-restricted and Vα24TCR-mediated manner. Hum Immunol 60:10, 1999.
7. Davodeau F, Peyrat MA, Necker A, Dominici R, Blanchard F, Leget C, Gaschet J, Costa P, Jacques Y, Godard A, Vie H, Poggi A, Romagne F, Bonneville M: Close phenotypic and functional similarities between human and murine αβ T cells expressing invariant TCR α-chains. J Immunol 158:5603, 1997.
8. + NKT cells activated by α-glycosylceramide-pulsed monocyte-derived dendritic cells. J Immunol 164:4458, 2000.
9. - T cells. J Exp Med 180:1171, 1994.
10. - and heterogeneous with respect to TCRβ expression. Hum Immunol 48:63, 1996.
11. + T cells. Curr Opin Immunol 7:367, 1995.
12. + T cell receptor α/β cells: new clues to their origin, specificity, and function. J Exp Med 182:633, 1995.
13. Bix M, Locksley RM: Natural T cells: cells that co-express NKRP-1 and TCR. J Immunol 155:1020, 1995.
14. Fowlkes BJ, Kruisbeek AM, Ton-That H, Weston MA, Coligan JE, Schwartz RH, Pardoll DM: A novel population of T cell receptor αβ-bearing thymocytes which predominantly expresses a single αβ gene family. Nature 329:251, 1987.
15. Budd RC, Miescher GC, Howe RC, Lees RK, Bron C, MacDonald HR: Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes. J Exp Med 166:577, 1987.
16. - T cells in mice and humans. J Exp Med 180:1097, 1994.
17. + thymocytes selected by MHC class I molecules. Science 263:1774, 1994.
18. α14 NKT cells by glycosylceramides. Science 278:1626, 1997.
19. + NKT lymphocytes. J Immunol 161:3271, 1998.
20. Prussin C, Foster B: TCR Vα24 and Vβ11 coexpression defines a human NK1 T cell analog containing a unique Th0 subpopulation. J Immunol 159:5862, 1997.
21. Karadimitris A, Gadola S, Altamirano M, Brown D, Woolfson A, Klenerman P, Chen JL, Koezuka Y, Roberts IA, Price DA, Dusheiko G, Milstein C, Fersht A, Luzzatto L, Cerundolo V: Human CD1d-glycolipid tetramers generated by in vitro oxidative refolding chromatography. Proc Natl Acad Sci USA 98:3294, 2001.
22. Tahir SM, Cheng O, Shaulov A, Koezuka Y, Bubley GJ, Wilson SB, Balk SP, Exley MA: Loss of IFN-γ production by invariant NK T cells in advanced cancer. J Immunol 167:4046, 2001.
23. Sumida T, Sakamoto A, Murata H, Makino Y, Takahashi H, Yoshida S, Nishioka K, Iwamoto I, Taniguchi M: Selective reduction of T cells bearing invariant Valpha24JalphaQ antigen receptor in patients with systemic sclerosis. J Exp Med 182:1163, 1995.
24. Wilson SB, Kent SC, Patton KT, Orban T, Jackson RA, Exley M, Porcelli S, Schatz DA, Atkinson MA, Balk SP, Strominger JL, Hafler DA: Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes. Nature 391:177, 1998.
25. Kojo S, Adachi Y, Keino H, Taniguchi M, Sumida T: Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases. Arthritis Rheum 44:1127, 2001.
26. Sandberg JK, Fast NM, Palacios EH, Fennelly G, Dobroszycki J, Palumbo P, Wiznia A, Grant RM, Bhardwaj N, Rosenberg MG, Nixon DF: Selective loss of innate CD4+ V{alpha}24 natural killer T cells in human immunodeficiency virus infection. J Virol 76:7528, 2002.
27. Motsinger A, Haas DW, Stanic AK, Van Kaer L, Joyce S, Unutmaz D: CDldrestricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection. J Exp Med 195:869, 2002.
28. van der Vliet HJ, von Blomberg BM, Hazenberg MD, Nishi N, Otto SA, van Benthem BH, Prins M, Claessen FA, van den Eertwegh AJ, Giaccone G, Miedema F, Scheper RJ, Pinedo HM: Selective decrease in circulating V alpha 24+V beta 11+ NKT cells during HIV type 1 infection. J Immunol 168:1490, 2002.
29. + NK T cells activated by α-galactosylceramide-pulsed monocyte-derived dendritic cells. J Immunol 168:3140, 2002.
30. - T cells bearing invariant Vα24JαQ TCR α-chain are decreased in patients with atopic diseases. Clin Exp Immunol 119:404, 2000.
31. Magnan A, Mely L, Prato S, Vervloet D, Romagne F, Camilla C, Necker A, Casano B, Montero-Jullian F, Fert V, Malissen B, Bongrand P: Relationships between natural T cells, atopy, IgE levels, and IL-4 production. Allergy 55:286, 2000.
32. Cui J, Watanabe N, Kawano T, Yamashita M, Kamata T, Shimizu C, Kimura M, Shimizu E, Koike J, Koseki H, Tanaka Y, Taniguchi M, Nakayama T: Inhibition of T helper cell type 2 cell differentiation and immunoglobulin E response by ligand-activated Vα14 natural killer T cells. J Exp Med 190:783, 1999.
33. Spergel JM, Mizoguchi E, Oettgen H, Bhan AK, Geha RS: Roles of TH1 and Th2 cytokine in a murine model of allergic dermatitis. J Clin Invest 103:1103, 1999.
34. Konishi H, Tsutsui H, Murakami T, Yumikura-Futatsugi S, Yamanaka K, Tanaka M, Iwakura Y, Suzuki N, Takeda K, Akira S, Nakanishi K, Mizutani H: IL-18 contributes to the spontaneous development of atopic dermatitis-like inflammatory skin lesion independently of IgE/stat6 under specific pathogen-free conditions. Proc Natl Acad Sci USA 99:11340, 2002.
35. Illes Z, Kondo T, Newcombe J, Oka N, Tabira T, Yamamura T: Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. J Immunol 164:4375, 2000.