Close Phenotypic and Functional Similarities Between Human and Murine αβ T Cells Expressing Invariant TCR α-Chains

Journal of Immunology

Volumn 158, Issue 12, 1997, Pages 5603-5611

  Davodeau, François ^a   Peyrat, Marie Alix ^a   Necker, Antje ^b   Dominici, Roberto ^a   Blanchard, Frédéric ^a   Leget, Corinne ^b   Gaschet, Joelle ^a,d   Costa, Paola ^c   Jacques, Yannick ^a   Godard, Anne ^a   Vié, Henri ^a   Poggi, Alessandro ^c   Romagné, François ^b   Bonneville, Marc ^a  

^a INSTITUT DE BIOLOGIE   (France)

^b Immunotech   (France)

^c UNIVERSITY OF GENOA   (Italy)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 4; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY;

ANIMAL; ARTICLE; BIOSYNTHESIS; HUMAN; IMMUNOLOGY; MOUSE; NATURAL KILLER CELL; PHENOTYPE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; ANTIGENS, CD8; HUMANS; INTERLEUKIN-4; KILLER CELLS, NATURAL; MICE; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 0031570534     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. + T cell receptor α/β cells: new clues to their origin, specificity, and function. J. Exp. Med. 182:633.
2. + T cells. Curr. Opin. Immunol. 7:367.
3. Bix, M., and R. M. Locksley. 1995. Natural T cells: cells that co-express NKRP-1 and TCR. J. Immunol. 155:1020.
4. Fowlkes, B. J., A. M. Kruisbeek, H. Ton-That, M. A. Weston, J. E. Coligan, R. H. Schwartz, and D. M. Pardoll. 1987. A novel population of T cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ8 gene family. Nature 329:251.
5. Budd, R. C., G. C. Miescher, R. C. Howe, R. K. Lees, C. Bron, and H. R. MacDonald. 1987. Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes. J. Exp. Med. 166:577.
6. - single-positive thymocyte subpopulation that expresses a highly skewed T cell antigen receptor family. Proc. Natl. Acad. Sci. USA 89:6506.
7. + thymocytes selected by MHC class I molecules. Science 263:1774.
8. - T cells in mice and humans. J. Exp. Med 180:1097.
9. + thymocytes. J. Exp. Med. 180:395.
10. + T cell receptor α/β cells in the liver of mice. J. Exp. Med. 180:699.
11. + T lymphocytes. Science 268:863.
12. Yoshimoto, T., and W. E. Paul. 1994. CD4pos NK1.1pos T cells promptly produce IL-4 in response to in vivo challenge with anti-CD3. J. Exp Med 179:1285.
13. + T cells in a Th2 response and in immunoglobulin E production. Science 270:1845.
14. Koseki, H., K. Inai, T. Ichikawa, I. Hayata, and M. Taniguchi. 1989. Predominant use of a particular α chain suppressor T cell hybridomas specific for keyhole limpet hemocyanin. Int. Immunol. 1:557.
15. - subset. J. Exp. Med. 177:1763.
16. - α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain. J. Exp. Med. 178:1.
17. - T cells. J. Exp. Med. 180:1171.
18. - and heterogeneous with respect to TCRβ expression. Hum. Immunol. 48:63.
19. Posnett, D. N., F. Romagné, A. Necker, B. L. Kotzin, and R. P. Sekaly. 1996. First human TcR monoclonal antibody workshop. Immunologist 4:5.
20. + immature thymocytes: NKRP1A-mediated regulation of proliferation and cytolytic activity. Eur. J. Immunol. 26:1266.
21. Moretta, A., M. Vitale, S. Sivori, C. Bottino, L. Morelli, R. Augugliaro, M. Barbaresi, D. Pende, E. Ciccone, M. Lopez-Botet, and L. Moretta. 1994. Human natural killer cell receptors for HLA class I molecules. Evidence that the Kp43 (CD94) molecule functions as receptor for HLA-B alleles. J. Exp. Med. 180:545.
22. + natural killer cells. Role in cell activation and regulation of cytolytic function. J. Exp. Med. 177:695.
23. + NK cells by the expression of clonally distributed functional surface molecules. Correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. J. Exp. Med. 172:1589.
24. + T lymphocyte subsets that express HLA class-I inhibitory receptors represent oligoclonally or monoclonally expanded cell populations. Proc. Natl. Acad. Sci. USA. In press.
25. Vié, H., S. Chevalier, R. Garand, J. P. Moisan, V. Praloran, M. C. Devilder, J. F. Moreau, and J. P. Soulillou. 1989. Clonal expansion of lymphocytes bearing the gamma/delta receptor in a patient with a large granular lymphocyte disorder. Blood 74:285.
26. Moreau, J. F., M. Bonneville, M. A. Peyrat, A. Godard, V. Jacques, C. Desgranges, and J. P. Soulillou. 1986. T lymphocyte cloning from rejected human kidney allografts. Frequency and functional/phenotypic analysis. J. Clin. Invest. 78:874.
27. Romagné, F., O. Kanagawa, J. David-Ameline, M. A. Peyrat, M. Bonneville, and A. Necker. 1995. TCRBV23 specificity of two monoclonal antibodies revealed by a panel of human Vβ chains expressed in mouse cells. J. Immunol. Methods 186:313.
28. Jung, T., U. Schauer, C. Heusser, C. Neumann, and C. Rieger. 1993. Detection of intracellular cytokines by flow cytometry. J. Immunol. Methods 159:197.
29. Davodeau, F., M. A. Peyrat, I. Houde, M. M. Hallet, H. Vié, and M. Bonneville. 1993. Peripheral selection of antigen receptor junctional features in a major human γδ T cell subset. Eur. J. Immunol. 23:804.
30. Davodeau, F., M. A. Peyrat, J. Gaschet, M. M. Hallet, F. Triebel, H. Vié, D. Kabelitz, and M. Bonneville. 1994. Surface expression of functional T cell receptor chains formed by interlocus recombination on human T lymphocytes. J. Exp. Med. 180:1685.
31. Charmley, P., K. Wang, L. Hood, and D. A. Nickerson. 1993. Identification and physical mapping of a polymorphic human TCR V beta gene with a frequent null allele. J. Exp. Med. 177:135.
32. Luyrink, L., C. A. Gabriel, S. D. Thompson, A. A. Grom, W. P. Maksymowych, E. Choi, and D. N. Glass. 1993. Reduced expression of a human V beta 6.1 T cell receptor allele. Proc. Natl. Acad. Sci. USA 90:4369.
33. Donahue, J. P., N. S. Ricalton, C. E. Behrendt, C. Rittershaus, S. Calaman, J. W. Kappler, B. L. Kotzin, and P. Marrack. 1994. Genetic analysis of low V beta 3 expression in humans. J. Exp. Med. 179:1701.
34. Lanier, L. L., C. Chang, and J. H. Phillips. 1994. Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J. Immunol. 153:2417.
35. Gaschet, J., M. A. Trevino, M. Cherel, R. Vivien, A. Garcia Sahuquillo, M. M. Hallet, M. Bonneville, R. Bragado, N. Milpied, and H. Vié. 1996. HLA-target antigens and TCR diversity of activated T cells invading the skin during acute GVH disease. Blood. 87:2345.
36. Bendelac, A., R. D. Hunziker, and O. Lantz. 1996. Increased interleukin-4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells. J. Exp. Med. 184:1285.
37. + cells in mouse liver. J. Exp. Med. 183:1277.
38. + thymocytes: a model based on T cell receptor avidity. Immunol. Today 16:428.
39. - T cells express oligoclonal TCRs, share junctional motifs across TCR Vβ gene families and phenotypically resemble memory T cells. Prof. Natl. Acad. Sci. USA 90: 11787.
40. + T cells selected by specific class I MHC antigen. Immunity 3:427.
41. + T cells upon NKR-P1 cross-linking. J. Exp. Med. 183: 2191.
42. Ryan, J. C., E. C. Niemi, M. C. Nakamura, and W. E. Seaman. 1995. NICR-P1A is a target-specific receptor that activates natural killer cell cytotoxioty. J. Exp. Med. 181:1911.
43. + T cells. Annu. Rev. Immunol. 12:635.
44. + T cells are not essential for T helper cell 2 immune responses. J. Exp. Med. 184:1295.
45. 2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses. J. Exp. Med. 184:1507.
46. + effector function against intracellular infection. J. Exp. Med. 184:131.
47. Haas, W., P. Pereira, and S. Tonegawa. 1993. Gamma/delta cells. Annu. Rev. Immunol. 11:637.
48. Mombaerts, P., J. Arnoldi, F. Russ, S. Tonegawa, and S. H. E. Kaufmann. 1993. Different roles of αβ and γδ T cells in immunity against an intracellular bacterial pathogen. Nature 365:53.