Human T cells expressing an invariant Vα24-JαQ TCRα are CD4- and heterogeneous with respect to TCRβ expression

Human Immunology

Volumn 48, Issue 1-2, 1996, Pages 63-67

  Porcelli, Steven ^b   Gerdes, Dirk ^a   Fertig, Alexis M ^a   Balk, Steven P ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ARTICLE; BETA CHAIN; CELLULAR IMMUNITY; GENE AMPLIFICATION; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LYMPHOCYTE SUBPOPULATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

EID: 0011022039     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/0198-8859(96)00090-0     Document Type: Article

References (14)

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2. Shivakumar S, Tsokos GC, Datta SK: T cell receptor α/β expressing double-negative (CD4-/CD8-) T helper cells in humans augment the production of pathogenic anti-DNAautoantibodies associated with lupus nephritis. J Immunol 143:103, 1989.
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8. Dellabona P, Padovan E, Casorati G, Brockhaus M, Lanzavecchia A: An invariant Vα24-αQ/Vβ11 T cell receptoris expressed in all individuals by clonally expanded CD4-8- T cells. J Exp Med 180:1171, 1994.
9. Koseki H, Hidefumi A, Inaba T, Miyashita N, Moriwaki K, Fischer Lindahl K, Mizutani Y, Imai K, Taniguchi M: Dominant expression of a distinctive V14+ T-cell receptor a chain in mice. Proc Natl Acad Sci USA 88:7518, 1991.
10. Lantz O, Bendelac A: An invariant T cell receptor a chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-CD8- T cells in mice and humans. J Exp Med 180:1097, 1994.
11. Bendelac A, Killeen N, Littman DR, Schwartz RH: A subset of CD4+ thymocytes selected by MHC class I molecules. Science 263:1774, 1994.
12. Adachi Y, Koseki H, Zijlstra M, Taniguchi M: Positive selection of invariant Vα 14+ T cells by non-major histocompatibility complex-encoded class I-like molecules expressed on bone marrow-derived cells. Proc Natl Acad Sci USA 92:1200, 1995.
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