Role of nitric oxide in inflammation-induced suppression of secretion in a mouse model of acute colitis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 275, Issue 6 38-6, 1998, Pages

  MacNaughton, Wallace K ^a,b   Lowe, Sonya S ^a   Cushing, Kelly ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Electrolyte transport; Enteric nervous system; Inducible nitric oxide synthase; Mice

Indexed keywords

MESSENGER RNA; MYELOPEROXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; COLON SECRETION; CONTROLLED STUDY; ELECTROLYTE TRANSPORT; ENZYME ACTIVITY; GENE EXPRESSION; INTESTINE INNERVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHORT CIRCUIT CURRENT;

EID: 0032444937     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1998.275.6.g1353     Document Type: Article

References (22)

1. Archampong, E. Q., J. Harris, and C. G. Clark. The absorption and secretion of water and electrolytes across the healthy and the diseased human colonic mucosa measured in vitro. Gut 13: 880-886, 1972.
2. Barry, M. K., J. D. Aloisi, S. P. Pickering, and C. J. Yeo. Nitric oxide modulates water and electrolyte transport in the ileum. Ann. Surg. 219: 382-388, 1994.
3. Bell, C. J., D. G. Gall, and J. L. Wallace. Disruption of colonic electrolyte transport in experimental colitis. Am. J. Physiol. 268 (Gastrointest. Liver Physiol. 31): G622-G630, 1995.
4. Boughton-Smith, N. K., S. M. Evans, and B. J. R. Whittle. Characterisation of nitric oxide synthase activity in the rat colonic mucosa and muscle after endotoxin and in a model of colitis. Agents Actions 2, Suppl. C: C223-C225, 1994.
5. Brown, D. R., and R. J. Miller. Neurohumoral control of fluid and electrolyte transport in intestinal mucosa. In: Handbook of Physiology. The Gastrointestinal System. Intestinal Absorption and Secretion. Bethesda, MD: Am. Physiol. Soc., 1991, sect. 6, vol. IV, chapt. 24, p. 527-590.
6. Brown, J. F., P. J. Hanson, and B. J. R. Whittle. Nitric oxide donors increase mucus gel thickness in rat stomach. Eur. J. Pharmacol. 223: 103-104, 1992.
7. Chin, K. W., and K. E. Barrett. Mast cells are not essential to inflammation in murine model of colitis. Dig. Dis. Sci. 39: 513-525, 1994.
8. Ciancio, M. J., and E. B. Chang. Epithelial secretory response to inflammation. Ann. NY Acad. Sci. 664: 210-221, 1992.
9. Connor, J. R., P. T. Manning, S. L. Settle, W. M. Moore, G. M. Jerome, R. K. Webber, F. S. Tjoeng, and M. G. Currie. Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur. J. Pharmacol. 273: 15-24, 1995.
10. Goldhill, J. M., R. Burakoff, V. Donovan, K. Rose, and W. H. Percy. Defective modulation of colonic secretomotor neurons in a rabbit model of colitis. Am. J. Physiol. 264 (Gastrointest. Liver Physiol. 27): G671-G677, 1993.
11. Guo, F. H., H. R. De Raeve, T. W. Rice, D. J. Stuehr, F. B. J. M. Thunnissen, and S. C. Erzurum. Continuous nitric oxide synthesis by inducible nitric oxide synthase in normal human airway epithelium in vivo. Proc. Natl. Acad. Sci. USA 92: 7809-7813, 1995.
12. Hawker, P. C., J. S. McKay, and L. A. Turnberg. Electrolyte transport across colonic mucosa from patients with inflammatory bowel disease. Gastroenterology 79: 508-511, 1980.
13. Hoffman, R. A., G. S. Zhang, N. C. Nüssler, S. L. Gleixner, H. R. Ford, R. L. Simmons, and S. C. Watkins. Constitutive expression of inducible nitric oxide synthase in the mouse ileal mucosa. Am. J. Physiol. 272 (Gastrointest. Liver Physiol. 35): G383-G392, 1997.
14. Holzer, P., I. T. Lippe, A. L. Tabrizi, L. Lénárd, Jr., and L. Barthó. Dual excitatory and inhibitory effect of nitric oxide on peristalsis in the guinea pig intestine. J. Pharmacol. Exp. Ther. 280: 154-161, 1997.
15. Howden, C. W., C. Robertson, A. Duncan, A. J. Morris, and R. I. Russell. Comparison of different measurements of intestinal permeability in inflammatory bowel disease. Am. J. Gastroenterol. 86: 1445-1449, 1991.
16. Hubel, K. A. The effects of electrical field stimulation and tetrodotoxin on ion transport by the isolated rabbit ileum. J. Clin. Invest. 62: 1039-1047, 1978.
17. Hubel, K. A. Electrical stimulus-secretion coupling in rabbit ileal mucosa. J. Pharmacol. Exp. Ther. 231: 577-582, 1984.
18. Hubel, K. A., and K. S. Renquist. Ion transport in normal and inflamed human jejunum in vitro. Changes with electrical field stimulation and theophylline. Dig. Dis. Sci. 35: 815-820, 1990.
19. Kimura, H., S. Miura, T. Shigematsu, N. Ohkubo, Y. Tsuzuki, I. Kurose, H. Higuchi, Y. Akiba, R. Hokari, M. Hirokawa, H. Serizawa, and H. Ishii. Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa of patients with active ulcerative colitis and Crohn's disease. Dig. Dis. Sci. 42: 1047-1054, 1997.
20. Kitagawa, H., F. Takeda, and H. Kohei. Effect of endothelium-derived relaxing factor on the gastric lesion induced by HCl in rats. J. Pharmacol. Exp. Ther. 253: 1133-1137, 1990.
21. Krawisz, J. E., P. Sharon, and W. F. Stenson. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 87: 1344-1350, 1984.
22. Lopez-Belmonte, J., B. J. R. Whittle, and S. Moncada. The actions of nitric oxide donors in the prevention or induction of injury to the rat gastric mucosa. Br. J. Pharmacol. 108: 73-78, 1993.