Rapid in vivo functional analysis of transgenes in mice using whole body imaging of luciferase expression

Transgenic Research

Volumn 10, Issue 5, 2001, Pages 423-434

  Zhang, Weisheng ^a   Feng, Jian Q ^b   Harris, Stephen E ^c   Contag, Pamela R ^d   Stevenson, David K ^a   Contag, Christopher H ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d Xenogen Corporation   (United States)

Author keywords

Bone morphogenic protein; Functional; Heme oxygenase; In vivo molecular imaging; Luciferase; Photoprotein; Reporter gene; Transgene

Indexed keywords

BACKCROSSING; BIOLUMINESCENCE; BIOMEDICAL ENGINEERING; CHEMICAL ANALYSIS; GENE FUNCTION; GENETIC LINE; GENETIC SCREENING; HEME OXYGENASE; HOMOZYGOTE; LUCIFERASE; POLYMERASE CHAIN REACTION; PROMOTER REGION; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; BONE MORPHOGENETIC PROTEINS; FEMALE; GENE EXPRESSION PROFILING; GENETIC ENGINEERING; HEME OXYGENASE (DECYCLIZING); HOMOZYGOTE; LUCIFERASES; LUMINESCENT MEASUREMENTS; MALE; MICE; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); TRANSGENES;

ANIMALIA; MUS MUSCULUS; RODENTIA;

EID: 0034783681     PISSN: 09628819     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012042506002     Document Type: Article

References (38)

1. Multiple elements within the 5′ distal enhancer of the mouse heine oxygenase-1 gene mediate induction by heavy metals
2. Developmental expression of heme oxygenase-1 (HSP32) in rat brain: An immunocytochemical study
3. A transgenic model of transactivation by the tax protein of HTLV-I
4. Molecular approaches involved in mammalian gene transfer: Evaluation of transgene expression
5. Novel features of Drosophila period transcription revealed by real-time luciferase reporting
6. Optical investigations of physiology: A study of intrinsic and extrinsic biomedical contrast
7. Bioluminescent reporters in living mammals
8. Visualizing gene expression in living mammals using a bioluminescent reporter
9. Photonic detection of bacterial pathogens in living hosts
10. Use of reporter genes for optical measurements of neoplastic disease in vivo
11. Noninvasive assessment of tumor cell proliferation in animal models
12. Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): Comparison of the structures and promoter regions of BMP-2 and BMP-4 genes
13. Genetic analysis of dorsoventral pattern formation in the zebrafish: Requirement of a BMP-like ventralizing activity and its dorsal repressor
14. Chemistries and colors of bioluminescent reactions: A review
15. Muscle creatine kinase sequence elements regulating skeletal and cardiac muscle expression in transgenic mice
16. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm
17. Utero delivery of adeno-associated viral vectors: Intraperitoneal gene transfer produces long-term expression
18. Expression and regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice
19. Transcriptional regulation of BMP-4 in the Xenopus embryo: Analysis of genomic BMP-4 and its promoter
20. A novel circadian phenotype based on firefly luciferase expression in transgenic plants
21. HIV-1 LTR activation model: Evaluation of various agents in skin of transgenic mice
22. In vivo activation of human immunodeficiency virus type 1 long terminal repeat by UV type A (UV-A) light plus psoralen and UV-B light in the skin of transgenic mice
23. In vivo analysis of the murine beta-myosin heavy chain gene promoter
24. Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging
25. Developmental biology of heme oxygenase
26. Cis-dominance of rat atrial natriuretic factor gene regulatory sequences in transgenic mice
27. Multiple circadian-regulated elements contribute to cycling period gene expression in Drosophila
28. Molecular approaches involved in mammalian gene transfer: Analysis of transgene integration
29. Thyroid hormone regulates expression of a transfected human alpha-myosin heavy chain fusion gene in fetal rat heart cells
30. Intestinal expression of the human apo A-I gene in transgenic mice is controlled by a DNA region 3′ to the gene in the promoter of adjacent convergently transcribed apo C-II gene
31. High levels of human apolipoprotein A-I in transgenic mice result in increased plasma levels of small high density lipoprotein (HDL) particles comparable to human HDL3
32. A role for BMP-4 in the development of subcutaneous cartilage
33. Bioluminescent and doxycycline-regulatable HO-1 expression in type II pneumocytes via transpulmonary delivery
34. Novel regulators of bone formation: Molecular clones and activities