Evaluation of reactive blue 2 derivatives as selective antagonists for P2Y receptors

Vascular Pharmacology

Volumn 39, Issue 6, 2002, Pages 309-315

  Brown, Julia ^a,b   Brown, Colin A ^a  

^a UNIVERSITY OF WOLVERHAMPTON   (United Kingdom)

^b KEELE UNIVERSITY   (United Kingdom)

Author keywords

Acid blue 129; Antagonists; Bovine aortic endothelial cells; P2Y1; P2Y2; Reactive blue 2

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; ACID BLUE 129; ACID BLUE 25; ACID BLUE 80; ACID VIOLET 34; CIBACRON BLUE F3GA; INOSITOL PHOSPHATE; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

ANIMAL CELL; AORTA; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0038309880     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1537-1891(03)00030-2     Document Type: Article

References (34)

1. Allsop D.J., Boarder M.R. Comparison of P2 purinergic receptors of aortic endothelial cells with those of adrenal medulla: Evidence for heterogeneity of receptor subtype and of inositol phosphate response. Mol. Pharmacol. 38:1990;84-91.
2. 2X-purinoceptors in rat urinary bladder. Br. J. Pharmacol. 112:1994;1151-1159.
3. Bo X., Schoepfer R., Burnstock G. Molecular cloning and characterization of a novel ATP P2X receptor subtype from embryonic chick skeletal muscle. J. Biol. Chem. 275:2000;14401-14407.
4. Boarder M.R., Hourani S.M.O. The regulation of vascular function by P2 receptors: multiple sites and multiple receptors. TIPS. 19:1998;99-107.
5. 1 receptor antagonist. Br. J. Pharmacol. 135:2002;2004-2010.
6. Brake A.J., Wagenbach M.J., Julius D. New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature. 371:1994;519-523.
7. 2U-purinoceptors. Br. J. Pharmacol. 116:1995;2413-2416.
8. Brown J., Reading S.J., Jones S., Fitchett C.J., Howl J., Martin A., Longland C.L., Michelangeli F., Dubrova Y.E., Brown C.A. Critical evaluation of ECV304 as a human endothelial cell model defined by genetic analysis and functional responses: a comparison with the human bladder cancer derived epithelial cell line T23/83. Lab. Invest. 80:2000;37-45.
9. 2-purinoceptor antagonists discriminate three contraction-mediating receptors for ATP in rat vas deferens. Naunyn-Schmiedeberg's Arch. Pharmacol. 349:1994;74-80.
10. 2-purinoceptor subtypes and ecto-nucleotidases by small aromatic isothiocyanato-sulphonates. Naunyn-Schmiedeberg's Arch. Pharmacol. 354:1996;481-490.
11. 2-purinoceptor subtypes and ecto-nucleotidases by compounds related to suramin. Naunyn-Schmiedeberg's Arch. Pharmacol. 354:1996;498-504.
12. 2 purinoceptors. Drug Dev. Res. 38:1996;67-71.
13. Burton S.J., Mcloughlin S.B., Stead C.V., Lowe C.R. Design and applications of biomimetic anthraquinone dyes: I. Synthesis and characterization of terminal isomers of C.I. reactive blue 2. J. Chromatogr. 435:1988;127-137.
14. 2 nucleotide receptor. J. Biol. Chem. 270:1995;26152-26158.
15. 2U-purinoceptors. Br. J. Pharmacol. 118:1996;704-710.
16. Chen B.C., Lee C.M., Lin W.W. Inhibition of ecto-ATPase by PPADS, suramin and reactive blue in endothelial cells, C6 glioma cells and RAW 264.7 macrophages. Br. J. Pharmacol. 119:1996;1628-1634.
17. 6 receptor. Biochem. Biophys. Res. Commun. 222:1996;303-308.
18. Communi D., Govaerts C., Parmentier M., Boeynaems J.-M. Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenyl cyclase. J. Biol. Chem. 272:1997;31969-31973.
19. 11 receptor. Br. J. Pharmacol. 128:1999;1199-1206.
20. Duchene A.D., Takeda K. P2Y and P2U mediated increases in internal calcium in single bovine aortic endothelial cells in primary culture. Endothelium. 5:1997;277-286.
21. Harden T.K., Barnard E.A., Boeynaems J.-M., Burnstock G., Dubyak G., Hourani S.M.O., Insel P.A. P2Y receptors. The IUPHAR Compendium of Receptor Characterization and Classification. 1998;209-217 IUPHAR Media, London.
22. Henderson D.J., Elliot D.G., Smith G.M., Webb T.E., Dainty I.A. Cloning and characterisation of a bovine P2Y receptor. Biochem. Biophys. Res. Commun. 212:1995;648-656.
23. Hollopeter G., Jantzen H.-M., Vincent D., Li G., England L., Ramakrishnan V., Yang R.-B., Nurden P., Nurden A., Julius D., Conley P.B. Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature. 409:2001;202-207.
24. 2T receptor: a novel approach to antithrombotic therapy. J. Med. Chem. 42:1999;213-220.
25. Michel A.D., Grahames C.B.A., Humphrey P.P.A. Functional characterization of P2 purinoceptors in PC12 cells by measurement of radiolabelled calcium influx. Naunyn-Schmiedeberg's Arch. Pharmacol. 354:1996;562-571.
26. 2U receptors in inositol phosphate response. Circ. Res. 72:1993;504-510.
27. Pirotton S., Communi D., Motte S., Janssens, Boeynaems J.M. Endothelial P2-purinoceptors: subtypes and signal transduction. J. Auton. Pharmacol. 16:1996;353-356.
28. 2X ATP receptor ion channel with widespread distribution in the brain. J. Neurosci. 15:1996;448-455.
29. 1 cells. J. Pharmacol. Exp. Ther. 292:2000;346-350.
30. 2Y purinoceptor. Eur. J. Pharmacol. 291:1995;281-289.
31. Tuluc F., Bültmann R., Glänzel M., Frahm A.W., Starke K. P2-receptor antagonists: IV. Blockade of P2-receptor subtypes and ecto-nucleotidases by compounds related to reactive blue 2. Naunyn Schmiedeberg's Arch. Pharmacol. 357:1998;111-120.
32. Webb T.E., Feolde E., Vigne P., Neary J.T., Runberg A., Frelin C., Barnard E.A. The P2Y purinoceptor in rat brain microvascular endothelial cells couple to inhibition of adenylate cyclase. Br. J. Pharmacol. 119:1996;1385-1392.
33. 2Y-purinoceptor and nucleotide receptor-induced relaxation of precontracted bovine aortic collateral artery rings: differential sensitivity to suramin and indomethacin. J. Exp. Ther. 268:1994;881-887.
34. 2-purinoceptor subtypes and ecto-nucleotidases by compounds related to Evans blue or trypan blue. Naunyn Schmiedeberg's Arch. Pharmacol. 354:1996;491-497.