Pyridoxal-phosphate-6-azophenyl-2',4'-disulfonate (PPADS), a putative P2Y1 receptor antagonist, blocks signaling at a site distal to the receptor in Madin-Darby canine kidney-D1 cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 292, Issue 1, 2000, Pages 346-350

  Shehnaz, Darakhshanda ^a   Torres, Brian ^a   Balboa, Maria A ^a   Insel, Paul A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYLTHIOADENOSINE TRIPHOSPHATE; ARACHIDONIC ACID; BRADYKININ; CALCIUM ION; CYCLIC AMP; IONOMYCIN; MELITTIN; NUCLEOTIDE; PHENYLEPHRINE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE A2; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE C; PURINE P2Y RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; THAPSIGARGIN; URIDINE TRIPHOSPHATE;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; BINDING SITE; BIOACCUMULATION; CALCIUM CELL LEVEL; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ARACHIDONIC ACID; BINDING SITES; CALCIUM; CELLS, CULTURED; CYCLIC AMP; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GTP-BINDING PROTEIN REGULATORS; KIDNEY; MELITTEN; PHOSPHOLIPASES A; PLATELET AGGREGATION INHIBITORS; PROTEIN KINASE C; PYRIDOXAL PHOSPHATE; RECEPTORS, PURINERGIC P2; URIDINE TRIPHOSPHATE;

EID: 0033962501     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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