Analysis of human IL-2/IL-2 receptor β chain interactions: Monoclonal antibody H2-8 and new IL-2 mutants define the critical role of α helix-A of IL-2

Cytokine

Volumn 9, Issue 7, 1997, Pages 488-498

  Eckenberg, Ralph ^a   Xu, Di ^b   Moreau, Jean Louis ^a   Bossus, Marc ^c   Mazié, Jean Claude ^a   Tartar, André ^c   Liu, Xin Yuan ^d   Alzari, Pedro M ^a   Bertoglio, Jacques ^b   Thèze, Jacques ^a  

^a INSTITUT PASTEUR   (France)

^b INSERM   (France)

^c INSTITUT PASTEUR DE LILLE   (France)

^d INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Function; IL 2 muteins; IL 2 receptors; IL 2 structure

Indexed keywords

CYTOKINE ANTIBODY; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; MONOCLONAL ANTIBODY; MUTANT PROTEIN;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BETA CHAIN; CONTROLLED STUDY; FEMALE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

EID: 0031194917     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.1996.0192     Document Type: Article

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