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Volumn 5, Issue 3, 2003, Pages 178-185

Targeting signaling pathways in heart failure by gene transfer

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CARIPORIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; NEUROHORMONE; PHOSPHOLAMBAN; POTASSIUM CHANNEL HERG;

EID: 0038258990     PISSN: 15233804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11883-003-0021-2     Document Type: Review
Times cited : (5)

References (84)
  • 1
    • 0036083657 scopus 로고    scopus 로고
    • Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray
    • Barrans JD, Allen PD, Stamatiou D, et al.: Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray. Am J Pathol 2002, 160:2035-2043.
    • (2002) Am. J. Pathol. , vol.160 , pp. 2035-2043
    • Barrans, J.D.1    Allen, P.D.2    Stamatiou, D.3
  • 2
    • 85047677277 scopus 로고
    • Developmental changes in energy substrate use by the heart
    • Lopaschuk GD, Collins-Nakai RL, Itoi T: Developmental changes in energy substrate use by the heart. Cardiovasc Res 1992, 26(12):1172-1180.
    • (1992) Cardiovasc. Res. , vol.26 , Issue.12 , pp. 1172-1180
    • Lopaschuk, G.D.1    Collins-Nakai, R.L.2    Itoi, T.3
  • 3
    • 0025173947 scopus 로고
    • Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes
    • Parker TG, Packer SE, Schneider MD: Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes. J Clin Invest 1990, 85:507-514.
    • (1990) J. Clin. Invest. , vol.85 , pp. 507-514
    • Parker, T.G.1    Packer, S.E.2    Schneider, M.D.3
  • 4
    • 0035846554 scopus 로고    scopus 로고
    • Metabolic gene expression in fetal and failing human heart
    • Razeghi P, Young ME, Alcorn JL, et al.: Metabolic gene expression in fetal and failing human heart. Circulation 2001, 104:2923-2931.
    • (2001) Circulation , vol.104 , pp. 2923-2931
    • Razeghi, P.1    Young, M.E.2    Alcorn, J.L.3
  • 5
    • 0026599924 scopus 로고
    • Developmental regulation of GLUT-1 (erythroid/Hep G2) and GLUT-4 (muscle/fat) glucose transporter expression in rat heart, skeletal muscle, and brown adipose tissue
    • Santalucia T, Camps M, Castello A, et al.: Developmental regulation of GLUT-1 (erythroid/Hep G2) and GLUT-4 (muscle/fat) glucose transporter expression in rat heart, skeletal muscle, and brown adipose tissue. Endocrinology 1992, 130:837-846.
    • (1992) Endocrinology , vol.130 , pp. 837-846
    • Santalucia, T.1    Camps, M.2    Castello, A.3
  • 6
    • 0028919740 scopus 로고
    • Myocardial lipid turnover in dilated cardiomyopathy: A dual in vivo tracer approach
    • Feinendegen LE, Henrich MM, Kuikka JT, et al.: Myocardial lipid turnover in dilated cardiomyopathy: a dual in vivo tracer approach. J Nucl Cardiol 1995, 2:42-52.
    • (1995) J. Nucl. Cardiol. , vol.2 , pp. 42-52
    • Feinendegen, L.E.1    Henrich, M.M.2    Kuikka, J.T.3
  • 8
    • 0342445429 scopus 로고    scopus 로고
    • Mitochondrial function in heart muscle from patients with idiopathic dilated cardiomyopathy
    • Jarreta D, Orus J, Barrientos A, et al.: Mitochondrial function in heart muscle from patients with idiopathic dilated cardiomyopathy. Cardiovasc Res 2000, 45:860-865.
    • (2000) Cardiovasc. Res. , vol.45 , pp. 860-865
    • Jarreta, D.1    Orus, J.2    Barrientos, A.3
  • 9
    • 0026463567 scopus 로고
    • Inherited idiopathic dilated cardiomyopathy with multiple deletions of mitochondrial DNA
    • Suomalainen A, Paetau A, Leinonen H, et al.: Inherited idiopathic dilated cardiomyopathy with multiple deletions of mitochondrial DNA. Lancet 1992, 340:1319-1320.
    • (1992) Lancet , vol.340 , pp. 1319-1320
    • Suomalainen, A.1    Paetau, A.2    Leinonen, H.3
  • 10
    • 0034602839 scopus 로고    scopus 로고
    • β(2)-adrenergic receptor overexpression exacerbates development of heart failure after aortic stenosis
    • Du XJ, Autelitano DJ, Dilley RJ, et al.: β(2)-adrenergic receptor overexpression exacerbates development of heart failure after aortic stenosis. Circulation 2000, 101:71-77.
    • (2000) Circulation , vol.101 , pp. 71-77
    • Du, X.J.1    Autelitano, D.J.2    Dilley, R.J.3
  • 11
    • 0036285606 scopus 로고    scopus 로고
    • Energy metabolism in the normal and failing heart: Potential for therapeutic interventions
    • Stanley WC, Chandler MP: Energy metabolism in the normal and failing heart: potential for therapeutic interventions. Heart Fail Rev 2002, 7:115-130.
    • (2002) Heart Fail. Rev. , vol.7 , pp. 115-130
    • Stanley, W.C.1    Chandler, M.P.2
  • 12
    • 0027312402 scopus 로고
    • Intracellular calcium homeostasis in cardiac myocytes
    • Barry WH, Bridge JH: Intracellular calcium homeostasis in cardiac myocytes. Circulation 1993, 87:1806-1815.
    • (1993) Circulation , vol.87 , pp. 1806-1815
    • Barry, W.H.1    Bridge, J.H.2
  • 13
    • 0029830352 scopus 로고    scopus 로고
    • Phospholamban: A prominent regulator of myocardial contractility
    • Koss KL, Kranias EG: Phospholamban: a prominent regulator of myocardial contractility. Circ Res 1996, 79:1059-1063.
    • (1996) Circ. Res. , vol.79 , pp. 1059-1063
    • Koss, K.L.1    Kranias, E.G.2
  • 14
    • 85047676620 scopus 로고
    • Relationship of abnormal intracellular calcium mobilisation to myocyte hypertrophy in human ventricular myocardium
    • Gwathmey JK, Bentivegna LA, Ransil BJ, et al.: Relationship of abnormal intracellular calcium mobilisation to myocyte hypertrophy in human ventricular myocardium. Cardiovasc Res 1993, 27:199-203.
    • (1993) Cardiovasc. Res. , vol.27 , pp. 199-203
    • Gwathmey, J.K.1    Bentivegna, L.A.2    Ransil, B.J.3
  • 15
    • 0027404510 scopus 로고
    • Sarcoplasmic reticulum calcium mobilization in right ventricular pressure-overload hypertrophy in the ferret: Relationships to diastolic dysfunction and a negative treppe
    • Gwathmey JK, Morgan JP: Sarcoplasmic reticulum calcium mobilization in right ventricular pressure-overload hypertrophy in the ferret: relationships to diastolic dysfunction and a negative treppe. Pflugers Arch 1993, 422:599-608.
    • (1993) Pflugers Arch. , vol.422 , pp. 599-608
    • Gwathmey, J.K.1    Morgan, J.P.2
  • 16
    • 0025169633 scopus 로고
    • Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure
    • Mercadier JJ, Lompre AM, Duc P, et al.: Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure. J Clin Invest 1990, 85:305-309.
    • (1990) J. Clin. Invest. , vol.85 , pp. 305-309
    • Mercadier, J.J.1    Lompre, A.M.2    Duc, P.3
  • 17
    • 0028101383 scopus 로고
    • Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium
    • Hasenfuss C, Reinecke H, Studer R, et al.: Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium. Circ Res 1994, 75:434-442.
    • (1994) Circ. Res. , vol.75 , pp. 434-442
    • Hasenfuss, C.1    Reinecke, H.2    Studer, R.3
  • 18
    • 0026542534 scopus 로고
    • Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure
    • Beuckelmann DJ, Nabauer M, Erdmann E: Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation 1992, 85:1046-1055.
    • (1992) Circulation , vol.85 , pp. 1046-1055
    • Beuckelmann, D.J.1    Nabauer, M.2    Erdmann, E.3
  • 19
    • 0034640113 scopus 로고    scopus 로고
    • PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): Defective regulation in failing hearts
    • Marx SO, Reiken S, Hisamatsu Y, et al.: PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 2000, 101:365-376.
    • (2000) Cell , vol.101 , pp. 365-376
    • Marx, S.O.1    Reiken, S.2    Hisamatsu, Y.3
  • 20
    • 0029932982 scopus 로고    scopus 로고
    • Functional relevance of an enhanced expression of the Na(+)-Ca2+ exchanger in the failing human heart
    • Flesch M, Putz F, Schwinger RH, Bohm M: Functional relevance of an enhanced expression of the Na(+)-Ca2+ exchanger in the failing human heart. Ann N Y Acad Sci 1996, 779:539-542.
    • (1996) Ann. N. Y. Acad. Sci. , vol.779 , pp. 539-542
    • Flesch, M.1    Putz, F.2    Schwinger, R.H.3    Bohm, M.4
  • 21
    • 0029809064 scopus 로고    scopus 로고
    • Evidence for functional relevance of an enhanced expression of the Na(+)-Ca2+ exchanger in failing human myocardium
    • Flesch M, Schwinger RH, Schiffer F, et al.: Evidence for functional relevance of an enhanced expression of the Na(+)-Ca2+ exchanger in failing human myocardium. Circulation 1996, 94:992-1002.
    • (1996) Circulation , vol.94 , pp. 992-1002
    • Flesch, M.1    Schwinger, R.H.2    Schiffer, F.3
  • 22
    • 0034730809 scopus 로고    scopus 로고
    • Impaired contractile performance of cultured rabbit ventricular myocytes after adenoviral gene transfer of Na(+)-Ca(2+) exchanger
    • Schillinger W, Janssen PM, Emami S, et al.: Impaired contractile performance of cultured rabbit ventricular myocytes after adenoviral gene transfer of Na(+)-Ca(2+) exchanger. Circ Res 2000, 87:581-587.
    • (2000) Circ. Res. , vol.87 , pp. 581-587
    • Schillinger, W.1    Janssen, P.M.2    Emami, S.3
  • 23
    • 0036839002 scopus 로고    scopus 로고
    • Structural and functional implications of the phospholamban hinge domain: Impaired SR Ca2+ uptake as a primary cause of heart failure
    • Schmidt AC, Zhai J, Carr AN, et al.: Structural and functional implications of the phospholamban hinge domain: impaired SR Ca2+ uptake as a primary cause of heart failure. Cardiovasc Res 2002, 56:248-259.
    • (2002) Cardiovasc. Res. , vol.56 , pp. 248-259
    • Schmidt, A.C.1    Zhai, J.2    Carr, A.N.3
  • 24
    • 0027360573 scopus 로고
    • The development of positive inotropic agents for chronic heart failure: How have we gone astray?
    • Packer M: The development of positive inotropic agents for chronic heart failure: how have we gone astray? J Am Coll Cardiol 1993, 22(4 suppl A):119A-126A.
    • (1993) J. Am. Coll. Cardiol. , vol.22 , Issue.4 SUPPL. A
    • Packer, M.1
  • 25
    • 0023035106 scopus 로고
    • Assessment of the beta-adrenergic receptor pathway in the intact failing human heart: Progressive receptor down-regulation and subsensitivity to agonist response
    • Fowler MB, Laser JA, Hopkins GL, et al.: Assessment of the beta-adrenergic receptor pathway in the intact failing human heart: progressive receptor down-regulation and subsensitivity to agonist response. Circulation 1986, 74:1290-1302.
    • (1986) Circulation , vol.74 , pp. 1290-1302
    • Fowler, M.B.1    Laser, J.A.2    Hopkins, G.L.3
  • 26
    • 0034636080 scopus 로고    scopus 로고
    • Catecholamines, cardiac beta-adrenergic receptors, and heart failure
    • Lefkowitz RJ, Rockman HA, Koch WJ: Catecholamines, cardiac beta-adrenergic receptors, and heart failure. Circulation 2000, 101:1634-1637.
    • (2000) Circulation , vol.101 , pp. 1634-1637
    • Lefkowitz, R.J.1    Rockman, H.A.2    Koch, W.J.3
  • 27
    • 0031669941 scopus 로고    scopus 로고
    • Molecular aspects of adrenergic signal transduction in cardiac failure
    • Hajjar RJ, Muller FU, Schmitz W, et al.: Molecular aspects of adrenergic signal transduction in cardiac failure. J Mol Med 1998, 76:747-755.
    • (1998) J. Mol. Med. , vol.76 , pp. 747-755
    • Hajjar, R.J.1    Muller, F.U.2    Schmitz, W.3
  • 28
    • 0037050009 scopus 로고    scopus 로고
    • Seven-transmem brane-spanning receptors and heart function
    • Rockman HA, Koch WJ, Lefkowitz RJ: Seven-transmem brane-spanning receptors and heart function. Nature 2002, 415:206-212.
    • (2002) Nature , vol.415 , pp. 206-212
    • Rockman, H.A.1    Koch, W.J.2    Lefkowitz, R.J.3
  • 29
    • 0007436490 scopus 로고    scopus 로고
    • Why does the myocardium fail? Insights from basic science
    • Bristow MR: Why does the myocardium fail? Insights from basic science. Lancet 1998, 352(suppl 1):SI8-SI14.
    • (1998) Lancet , vol.352 , Issue.SUPPL. 1
    • Bristow, M.R.1
  • 30
    • 0030613761 scopus 로고    scopus 로고
    • Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A
    • Daaka Y, Luttrell LM, Lefkowitz RJ: Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A. Nature 1997, 390:88-91.
    • (1997) Nature , vol.390 , pp. 88-91
    • Daaka, Y.1    Luttrell, L.M.2    Lefkowitz, R.J.3
  • 31
    • 0035852634 scopus 로고    scopus 로고
    • Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes
    • Zhu WZ, Zheng M, Koch WJ, et al.: Dual modulation of cell survival and cell death by beta(2)-adrenergic signaling in adult mouse cardiac myocytes. Proc Natl Acad Sci U S A 2001, 98:1607-1612.
    • (2001) Proc. Natl. Acad. Sci. U S A , vol.98 , pp. 1607-1612
    • Zhu, W.Z.1    Zheng, M.2    Koch, W.J.3
  • 32
    • 0033535942 scopus 로고    scopus 로고
    • Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice
    • Engelhardt S, Hein L, Wiesmann F, Lohse MJ: Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice. Proc Natl Acad Sci U S A 1999, 96:7059-7064.
    • (1999) Proc. Natl. Acad. Sci. U S A , vol.96 , pp. 7059-7064
    • Engelhardt, S.1    Hein, L.2    Wiesmann, F.3    Lohse, M.J.4
  • 33
    • 0034636061 scopus 로고    scopus 로고
    • Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: Critical role for expression level
    • Liggett SB, Tepe NM, Lorenz JN, et al.: Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts: critical role for expression level. Circulation 2000, 101:1707-1714.
    • (2000) Circulation , vol.101 , pp. 1707-1714
    • Liggett, S.B.1    Tepe, N.M.2    Lorenz, J.N.3
  • 34
    • 17444439098 scopus 로고    scopus 로고
    • Polymorphisms of the beta(2)-adrenergic receptor determine exercise capacity in patients with heart failure
    • Wagoner LE, Craft LL, Singh B, et al.: Polymorphisms of the beta(2)-adrenergic receptor determine exercise capacity in patients with heart failure. Circ Res 2000, 86:834-840.
    • (2000) Circ. Res. , vol.86 , pp. 834-840
    • Wagoner, L.E.1    Craft, L.L.2    Singh, B.3
  • 35
    • 0032531426 scopus 로고    scopus 로고
    • The Ile 164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure
    • Liggett SB, Wagoner LE, Craft LL, et al.: The Ile 164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure. J Clin Invest 1998, 102:1534-1539.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1534-1539
    • Liggett, S.B.1    Wagoner, L.E.2    Craft, L.L.3
  • 36
    • 0031016557 scopus 로고    scopus 로고
    • Physiological effects of adenoviral gene transfer of sarcoplasmic reticulum calcium ATPase in isolated rat myocytes
    • Hajjal RJ, Kang JX, Gwathmey JK, Rosenzweig A: Physiological effects of adenoviral gene transfer of sarcoplasmic reticulum calcium ATPase in isolated rat myocytes. Circulation 1997, 95:423-429.
    • (1997) Circulation , vol.95 , pp. 423-429
    • Hajjal, R.J.1    Kang, J.X.2    Gwathmey, J.K.3    Rosenzweig, A.4
  • 37
    • 0033383744 scopus 로고    scopus 로고
    • Comparison of SERCA1 and SERCA2a expressed in COS-1 cells and cardiac myocytes
    • Sumbilla C, Cavagna M, Zhong L, et al.: Comparison of SERCA1 and SERCA2a expressed in COS-1 cells and cardiac myocytes. Am J Physiol 1999, 277(6 Pt 2):H2381-H2391.
    • (1999) Am. J. Physiol. , vol.277 , Issue.6 PART 2
    • Sumbilla, C.1    Cavagna, M.2    Zhong, L.3
  • 38
    • 0030767865 scopus 로고    scopus 로고
    • Adenoviral gene transfer of phospholamban in isolated rat cardiomyocytes. Rescue effects by concomitant gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase
    • Hajjar RJ, Schmidt U, Kang JX, et al.: Adenoviral gene transfer of phospholamban in isolated rat cardiomyocytes. Rescue effects by concomitant gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase. Circ Res 1997, 81:145-153.
    • (1997) Circ. Res. , vol.81 , pp. 145-153
    • Hajjar, R.J.1    Schmidt, U.2    Kang, J.X.3
  • 39
    • 0035908945 scopus 로고    scopus 로고
    • Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure
    • del Monte F, Williams E, Lebeche D, et al.: Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure. Circulation 2001, 104:1424-1429.
    • (2001) Circulation , vol.104 , pp. 1424-1429
    • del Monte, F.1    Williams, E.2    Lebeche, D.3
  • 40
    • 0035253781 scopus 로고    scopus 로고
    • Adenoviral SERCA1a gene transfer to adult rat ventricular myocytes induces physiological changes in calcium handling
    • Chossat N, Griscelli F, Jourdon P, et al.: Adenoviral SERCA1a gene transfer to adult rat ventricular myocytes induces physiological changes in calcium handling. Cardiovasc Res 2001, 49:288-297.
    • (2001) Cardiovasc. Res. , vol.49 , pp. 288-297
    • Chossat, N.1    Griscelli, F.2    Jourdon, P.3
  • 41
    • 12944332074 scopus 로고    scopus 로고
    • Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure
    • Miyamoto MI, del Monte F, Schmidt U, et al.: Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure. Proc Natl Acad Sci U S A 2000, 97:793-798.
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , pp. 793-798
    • Miyamoto, M.I.1    del Monte, F.2    Schmidt, U.3
  • 42
    • 0033621151 scopus 로고    scopus 로고
    • Effects of mutant and antisense RNA of phospholamban on SR Ca(2+)- ATPase activity and cardiac myocyte contractility
    • He H, Meyer M, Martin JL, et al.: Effects of mutant and antisense RNA of phospholamban on SR Ca(2+)- ATPase activity and cardiac myocyte contractility. Circulation 1999, 100:974-980.
    • (1999) Circulation , vol.100 , pp. 974-980
    • He, H.1    Meyer, M.2    Martin, J.L.3
  • 43
    • 0036341380 scopus 로고    scopus 로고
    • Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery
    • Hoshijima M, Ikeda Y, Iwanaga Y, et al.: Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med 2002, 8:864-871.
    • (2002) Nat. Med. , vol.8 , pp. 864-871
    • Hoshijima, M.1    Ikeda, Y.2    Iwanaga, Y.3
  • 44
    • 0035254550 scopus 로고    scopus 로고
    • Adenovirus gene transfer of SERCA in heart failure. A promising therapeutic approach?
    • Baartscheer A: Adenovirus gene transfer of SERCA in heart failure. A promising therapeutic approach? Cardiovasc Res 2001, 49:249-252.
    • (2001) Cardiovasc. Res. , vol.49 , pp. 249-252
    • Baartscheer, A.1
  • 45
    • 0026516483 scopus 로고
    • Role of cardiac angiotensin II in isoproterenol-induced left ventricular hypertrophy
    • Nagano M, Higaki J, Nakamura F, et al.: Role of cardiac angiotensin II in isoproterenol-induced left ventricular hypertrophy. Hypertension 1992, 19(6 Pt 2):708-712.
    • (1992) Hypertension , vol.19 , Issue.6 PART 2 , pp. 708-712
    • Nagano, M.1    Higaki, J.2    Nakamura, F.3
  • 46
    • 0027945391 scopus 로고
    • Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats
    • Golomb E, Abassi ZA, Coca G, et al.: Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats. Am J Physiol 1994, 267(4 Pt 2):H1496-H1506.
    • (1994) Am. J. Physiol. , vol.267 , Issue.4 PART 2
    • Golomb, E.1    Abassi, Z.A.2    Coca, G.3
  • 47
    • 0035665486 scopus 로고    scopus 로고
    • Isoproterenol-induced cardiac hypertrophy: Role of circulatory versus cardiac renin-angiotensin system
    • Leenen FH, White R, Yuan B: Isoproterenol-induced cardiac hypertrophy: role of circulatory versus cardiac renin-angiotensin system. Am J Physiol Heart Circ Physiol 2001, 281:H2410-H2416.
    • (2001) Am. J. Physiol. Heart Circ. Physiol. , vol.281
    • Leenen, F.H.1    White, R.2    Yuan, B.3
  • 48
    • 0037134401 scopus 로고    scopus 로고
    • Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice
    • Engelhardt S, Hein L, Keller U, et al.: Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice. Circ Res 2002, 90:814-819.
    • (2002) Circ. Res. , vol.90 , pp. 814-819
    • Engelhardt, S.1    Hein, L.2    Keller, U.3
  • 49
    • 0033559392 scopus 로고    scopus 로고
    • Overexpression of a human potassium channel suppresses cardiac hyperexcitability in rabbit ventricular myocytes
    • Nuss HB, Marban E, Johns DC: Overexpression of a human potassium channel suppresses cardiac hyperexcitability in rabbit ventricular myocytes. J Clin Invest 1999, 103:889-896.
    • (1999) J. Clin. Invest. , vol.103 , pp. 889-896
    • Nuss, H.B.1    Marban, E.2    Johns, D.C.3
  • 50
    • 0032574746 scopus 로고    scopus 로고
    • Modulation of ventricular function through gene transfer in vivo
    • Hajjar RJ, Schmidt U, Matsui T, et al.: Modulation of ventricular function through gene transfer in vivo. Proc Natl Acad Sci U S A 1998, 95:5251-5256.
    • (1998) Proc. Natl. Acad. Sci. U S A , vol.95 , pp. 5251-5256
    • Hajjar, R.J.1    Schmidt, U.2    Matsui, T.3
  • 51
    • 0032745831 scopus 로고    scopus 로고
    • Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery
    • Maurice JP, Hata JA, Shah AS, et al.: Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery. J Clin Invest 1999, 104:21-29.
    • (1999) J. Clin. Invest. , vol.104 , pp. 21-29
    • Maurice, J.P.1    Hata, J.A.2    Shah, A.S.3
  • 52
    • 17344389993 scopus 로고    scopus 로고
    • Intracoronary adenovirus-mediated delivery and overexpression of the beta (2)-adrenergic receptor in the heart: Prospects for molecular ventricular assistance
    • Shah AS, Lilly RE, Kypson AP, et al.: Intracoronary adenovirus-mediated delivery and overexpression of the beta (2)-adrenergic receptor in the heart: prospects for molecular ventricular assistance. Circulation 2000, 101:408-414.
    • (2000) Circulation , vol.101 , pp. 408-414
    • Shah, A.S.1    Lilly, R.E.2    Kypson, A.P.3
  • 53
    • 0029061324 scopus 로고
    • Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor
    • Koch WJ, Rockman HA, Samama P, et al.: Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science 1995, 268:1350-1353.
    • (1995) Science , vol.268 , pp. 1350-1353
    • Koch, W.J.1    Rockman, H.A.2    Samama, P.3
  • 54
    • 0032499733 scopus 로고    scopus 로고
    • Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice
    • Rockman HA, Chien KR, Choi DJ, et al.: Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Proc Natl Acad Sci U S A 1998, 95:7000-7005.
    • (1998) Proc Natl. Acad. Sci. U S A , vol.95 , pp. 7000-7005
    • Rockman, H.A.1    Chien, K.R.2    Choi, D.J.3
  • 55
    • 0030726783 scopus 로고    scopus 로고
    • Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer
    • Akhter SA, Skaer CA, Kypson AP, et al.: Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer. Proc Natl Acad Sci U S A 1997, 94:12100-12105.
    • (1997) Proc. Natl. Acad. Sci. U S A , vol.94 , pp. 12100-12105
    • Akhter, S.A.1    Skaer, C.A.2    Kypson, A.P.3
  • 56
    • 0034625008 scopus 로고    scopus 로고
    • Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
    • White DC, Hata JA, Shah AS, et al.: Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction. Proc Natl Acad Sci U S A 2000, 97:5428-5433.
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , pp. 5428-5433
    • White, D.C.1    Hata, J.A.2    Shah, A.S.3
  • 57
    • 0035814968 scopus 로고    scopus 로고
    • In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction
    • Shah AS, White DC, Emani S, et al.: In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction. Circulation 2001, 103:1311-1316.
    • (2001) Circulation , vol.103 , pp. 1311-1316
    • Shah, A.S.1    White, D.C.2    Emani, S.3
  • 58
    • 0034681226 scopus 로고    scopus 로고
    • Gβγ-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy
    • Naga Prasad SV, Esposito G, Mao L, et al.: Gβγ-dependent phosphoinositide 3-kinase activation in hearts with in vivo pressure overload hypertrophy. J Biol Chem 2000, 275:4693-4698.
    • (2000) J. Biol. Chem. , vol.275 , pp. 4693-4698
    • Naga Prasad, S.V.1    Esposito, G.2    Mao, L.3
  • 59
    • 17144439543 scopus 로고    scopus 로고
    • Enhanced cardiac contractility after gene transfer of V2 vasopressin receptors in vivo by ultrasound-guided injection or transcoronary delivery
    • Weig HJ, Laugwitz KL, Moretti A, et al.: Enhanced cardiac contractility after gene transfer of V2 vasopressin receptors in vivo by ultrasound-guided injection or transcoronary delivery. Circulation 2000, 101:1578-1585.
    • (2000) Circulation , vol.101 , pp. 1578-1585
    • Weig, H.J.1    Laugwitz, K.L.2    Moretti, A.3
  • 60
    • 0345120936 scopus 로고    scopus 로고
    • Cardiac-directed adenylyl cyclase expression improves heart function in murine cardiomyopathy
    • Roth DM, Gao MH, Lai NC, et al.: Cardiac-directed adenylyl cyclase expression improves heart function in murine cardiomyopathy. Circulation 1999, 99:3099-3102.
    • (1999) Circulation , vol.99 , pp. 3099-3102
    • Roth, D.M.1    Gao, M.H.2    Lai, N.C.3
  • 61
    • 0030048713 scopus 로고    scopus 로고
    • Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure
    • Sharov VG, Sabbah HN, Shimoyama H, et al.: Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure. Am J Pathol 1996, 148:141-149.
    • (1996) Am. J. Pathol. , vol.148 , pp. 141-149
    • Sharov, V.G.1    Sabbah, H.N.2    Shimoyama, H.3
  • 62
    • 0029778441 scopus 로고    scopus 로고
    • Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction
    • Misao J, Hayakawa Y, Ohno M, et al.: Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation 1996, 94:1506-1512.
    • (1996) Circulation , vol.94 , pp. 1506-1512
    • Misao, J.1    Hayakawa, Y.2    Ohno, M.3
  • 63
    • 0001844965 scopus 로고    scopus 로고
    • Rescue of dialted cardiomyopathy by caspase inhibition in FKBP-caspase-8 transgenic mice
    • Wencker D, Chandra M, Armstrong R, et al.: Rescue of dialted cardiomyopathy by caspase inhibition in FKBP-caspase-8 transgenic mice. Circulation 1999, 102:II-28.
    • (1999) Circulation , vol.102
    • Wencker, D.1    Chandra, M.2    Armstrong, R.3
  • 64
    • 0032526374 scopus 로고    scopus 로고
    • Apoptosis: Basic mechanisms and implications for cardiovascular disease
    • Haunstetter A, Izumo S: Apoptosis: basic mechanisms and implications for cardiovascular disease. Circ Res 1998, 82:1111-1129.
    • (1998) Circ. Res. , vol.82 , pp. 1111-1129
    • Haunstetter, A.1    Izumo, S.2
  • 65
    • 0030870555 scopus 로고    scopus 로고
    • The bcl-2 gene product prevents programmed cell death of ventricular myocytes
    • Kirshenbaum LA, de Moissac D: The bcl-2 gene product prevents programmed cell death of ventricular myocytes. Circulation 1997, 96:1580-1585.
    • (1997) Circulation , vol.96 , pp. 1580-1585
    • Kirshenbaum, L.A.1    de Moissac, D.2
  • 66
    • 0010034895 scopus 로고    scopus 로고
    • Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury
    • Brocheriou V, Hagege AA, Oubenaissa A, et al.: Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury. J Gene Med 2000, 2:326-333.
    • (2000) J. Gene Med. , vol.2 , pp. 326-333
    • Brocheriou, V.1    Hagege, A.A.2    Oubenaissa, A.3
  • 67
    • 0033534088 scopus 로고    scopus 로고
    • Adenoviral gene transfer of activated phosphatidylinositol 3′-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro
    • Matsui T, Li L, del Monte F, et al.: Adenoviral gene transfer of activated phosphatidylinositol 3′-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro. Circulation 1999, 100:2373-2379.
    • (1999) Circulation , vol.100 , pp. 2373-2379
    • Matsui, T.1    Li, L.2    del Monte, F.3
  • 68
    • 0034651983 scopus 로고    scopus 로고
    • Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart
    • Fujio Y, Nguyen T, Wencker D, et al.: Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. Circulation 2000, 101:660-667.
    • (2000) Circulation , vol.101 , pp. 660-667
    • Fujio, Y.1    Nguyen, T.2    Wencker, D.3
  • 69
    • 0031568949 scopus 로고    scopus 로고
    • Angiotensin II activates programmed myocyte cell death in vitro
    • Cigola E, Kajstura J, Li B, et al.: Angiotensin II activates programmed myocyte cell death in vitro. Exp Cell Res 1997, 231:363-371.
    • (1997) Exp. Cell Res. , vol.231 , pp. 363-371
    • Cigola, E.1    Kajstura, J.2    Li, B.3
  • 70
    • 0030817798 scopus 로고    scopus 로고
    • Angiotensin II induces apoptosis of human endothelial cells Protective effect of nitric oxide
    • Dimmeler S, Rippmann V, Weiland U, et al.: Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide. Circ Res 1997, 81:970-976.
    • (1997) Circ. Res. , vol.81 , pp. 970-976
    • Dimmeler, S.1    Rippmann, V.2    Weiland, U.3
  • 71
    • 0001739436 scopus 로고    scopus 로고
    • Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell
    • Leri A, Claudio PP, Li Q, el al.: Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest 1998, 101:1326-1342.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1326-1342
    • Leri, A.1    Claudio, P.P.2    Li, Q.3
  • 72
    • 0028905583 scopus 로고
    • Bradykinin antagonism inhibits the antigrowth effect of converting enzyme inhibition in the dog myocardium after discrete transmural myocardial necrosis
    • McDonald KM, Mock J, D'Aloia A, et al.: Bradykinin antagonism inhibits the antigrowth effect of converting enzyme inhibition in the dog myocardium after discrete transmural myocardial necrosis. Circulation 1995, 91:2043-2048.
    • (1995) Circulation , vol.91 , pp. 2043-2048
    • McDonald, K.M.1    Mock, J.2    D'Aloia, A.3
  • 73
    • 0030948469 scopus 로고    scopus 로고
    • Differential effects of kinins on cardiomyocyte hypertrophy and interstitial collagen matrix in the surviving myocardium after myocardial infarction in the rat
    • Wollert KC, Studer R, Doerfer K, et al.: Differential effects of kinins on cardiomyocyte hypertrophy and interstitial collagen matrix in the surviving myocardium after myocardial infarction in the rat. Circulation 1997, 95:1910-1917.
    • (1997) Circulation , vol.95 , pp. 1910-1917
    • Wollert, K.C.1    Studer, R.2    Doerfer, K.3
  • 74
    • 0031003230 scopus 로고    scopus 로고
    • Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. Role of kinins and angiotensin II type 2 receptors
    • Liu YH, Yang XP, Sharov VG, et al.: Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. Role of kinins and angiotensin II type 2 receptors. J Clin Invest 1997, 99:1926-1935.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1926-1935
    • Liu, Y.H.1    Yang, X.P.2    Sharov, V.G.3
  • 75
    • 0033958237 scopus 로고    scopus 로고
    • Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion
    • Yoshida H, Zhang JJ, Chao L, Chao J: Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion. Hypertension 2000, 35(1 Pt 1):25-31.
    • (2000) Hypertension , vol.35 , Issue.1 PART 1 , pp. 25-31
    • Yoshida, H.1    Zhang, J.J.2    Chao, L.3    Chao, J.4
  • 76
    • 0036841281 scopus 로고    scopus 로고
    • Kallikrein gene delivery improves cardiac reserve and attenuates remodeling after myocardial infarction
    • Agata J, Chao L, Chao J: Kallikrein gene delivery improves cardiac reserve and attenuates remodeling after myocardial infarction. Hypertension 2002, 40:653-659.
    • (2002) Hypertension , vol.40 , pp. 653-659
    • Agata, J.1    Chao, L.2    Chao, J.3
  • 77
    • 0036215654 scopus 로고    scopus 로고
    • Effective gene transfer to solid tumors using different nonviral gene delivery techniques: Electroporation, liposomes, and integrin-targeted vector
    • Cemazar M, Sersa G, Wilson J, et al.: Effective gene transfer to solid tumors using different nonviral gene delivery techniques: electroporation, liposomes, and integrin-targeted vector. Cancer Gene Ther 2002, 9:399-406.
    • (2002) Cancer Gene Ther. , vol.9 , pp. 399-406
    • Cemazar, M.1    Sersa, G.2    Wilson, J.3
  • 78
    • 0034567667 scopus 로고    scopus 로고
    • Production of recombinant adeno-associated virus
    • Gao GP, Wilson JM, Wivel NA: Production of recombinant adeno-associated virus. Adv Virus Res 2000, 55:529-543.
    • (2000) Adv. Virus Res. , vol.55 , pp. 529-543
    • Gao, G.P.1    Wilson, J.M.2    Wivel, N.A.3
  • 79
    • 0037049981 scopus 로고    scopus 로고
    • Myocardial gene therapy
    • Isner JM: Myocardial gene therapy. Nature 2002, 415:234-239.
    • (2002) Nature , vol.415 , pp. 234-239
    • Isner, J.M.1
  • 81
    • 0030912001 scopus 로고    scopus 로고
    • Adeno-associated virus vectors for vascular gene delivery
    • Lynch CM, Hara PS, Leonard JC, et al.: Adeno-associated virus vectors for vascular gene delivery. Circ Res 1997, 80:497-505.
    • (1997) Circ. Res. , vol.80 , pp. 497-505
    • Lynch, C.M.1    Hara, P.S.2    Leonard, J.C.3
  • 82
    • 0035988801 scopus 로고    scopus 로고
    • Highly purified recombinant adeno-associated virus vectors. Preparation and quantitation
    • Schnepp B, Clark KR: Highly purified recombinant adeno-associated virus vectors. Preparation and quantitation. Methods Mol Med 2002, 69:427-443.
    • (2002) Methods Mol. Med. , vol.69 , pp. 427-443
    • Schnepp, B.1    Clark, K.R.2
  • 83
    • 0035988792 scopus 로고    scopus 로고
    • Development of replication-defective herpes simplex virus vectors
    • Goins WF, Krisky DM, Wolfe DP, et al.: Development of replication-defective herpes simplex virus vectors. Methods Mol Med 2002, 69:481-507.
    • (2002) Methods Mol. Med. , vol.69 , pp. 481-507
    • Goins, W.F.1    Krisky, D.M.2    Wolfe, D.P.3
  • 84
    • 0343111918 scopus 로고    scopus 로고
    • Regional myocardial gene transfer using high efficency with selective pressure-regulated retroinfusion of coronary veins
    • Boeckstegers P, von Degenfeld G, Heinrich D, et al.: Regional myocardial gene transfer using high efficency with selective pressure-regulated retroinfusion of coronary veins. Circulation 1999, 100(suppl I):I-815.
    • (1999) Circulation , vol.100 , Issue.SUPPL. I
    • Boeckstegers, P.1    von Degenfeld, G.2    Heinrich, D.3


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