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Volumn 987, Issue , 2003, Pages 188-198

Co-stimulatory blockade in the treatment of murine systemic lupus erythematosus (SLE)

Author keywords

B cells; Co stimulatory blockade; SLE

Indexed keywords

ANTIBODY; ANTIGEN; CD40 LIGAND; CYCLOPHOSPHAMIDE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DOUBLE STRANDED DNA; HYBRID PROTEIN; ICOS IMMUNOGLUBULIN; IMMUNOGLOBULIN G; PD 1 LIGAND IMMUNOGLOBULIN; REAGENT; TACI IMMUNOGLOBULIN; UNCLASSIFIED DRUG;

EID: 0038240916     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2003.tb06048.x     Document Type: Conference Paper
Times cited : (35)

References (45)
  • 1
    • 0033932756 scopus 로고    scopus 로고
    • CTLA4Ig inhibits T cell-dependent B-cell maturation in murine systemic lupus erythematosus
    • MIHARA, M. et al. 2000. CTLA4Ig inhibits T cell-dependent B-cell maturation in murine systemic lupus erythematosus. J. Clin. Invest. 106: 91-101.
    • (2000) J. Clin. Invest. , vol.106 , pp. 91-101
    • Mihara, M.1
  • 2
    • 0037083423 scopus 로고    scopus 로고
    • Mechanism of action of combined short term CTLA4Ig and anti-CD40L in murine SLE
    • WANG, X. et al. 2002. Mechanism of action of combined short term CTLA4Ig and anti-CD40L in murine SLE. J. Immunol. 168: 2046-2053.
    • (2002) J. Immunol. , vol.168 , pp. 2046-2053
    • Wang, X.1
  • 3
    • 0029052398 scopus 로고
    • Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers
    • HAN, S. et al. 1995. Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. J. Immunol. 155: 556-567.
    • (1995) J. Immunol. , vol.155 , pp. 556-567
    • Han, S.1
  • 4
    • 0034192092 scopus 로고    scopus 로고
    • The roles of CD28 and CD40 ligand in T cell activation and tolerance
    • HOWLAND, K.C. et al. 2000. The roles of CD28 and CD40 ligand in T cell activation and tolerance. J. Immunol. 164: 4465-4470.
    • (2000) J. Immunol. , vol.164 , pp. 4465-4470
    • Howland, K.C.1
  • 5
    • 0028298229 scopus 로고
    • gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory
    • FOY, T.M. et al. 1994. gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory. J. Exp. Med. 180: 157-163.
    • (1994) J. Exp. Med. , vol.180 , pp. 157-163
    • Foy, T.M.1
  • 6
    • 0033375952 scopus 로고    scopus 로고
    • CD154 (CD40L) induces human endothelial cell chemokine production and migration of leukocyte subsets
    • THIENEL, U., J. LOIKE & M.J. YELLIN. 1999. CD154 (CD40L) induces human endothelial cell chemokine production and migration of leukocyte subsets. Cell. Immunol. 198: 87-95.
    • (1999) Cell. Immunol. , vol.198 , pp. 87-95
    • Thienel, U.1    Loike, J.2    Yellin, M.J.3
  • 7
    • 0032530746 scopus 로고    scopus 로고
    • Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production
    • SCHWEITZER, A.N. & A.H. SHARPE. 1998. Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production. J. Immunol. 161: 2762-2771.
    • (1998) J. Immunol. , vol.161 , pp. 2762-2771
    • Schweitzer, A.N.1    Sharpe, A.H.2
  • 8
    • 0035957189 scopus 로고    scopus 로고
    • The effect of CD28/B7 blockade on alloreactive T and B cells after liver cell transplantation
    • REDDY, B. et al. 2001. The effect of CD28/B7 blockade on alloreactive T and B cells after liver cell transplantation. Transplantation 71: 801-811.
    • (2001) Transplantation , vol.71 , pp. 801-811
    • Reddy, B.1
  • 9
    • 0036214017 scopus 로고    scopus 로고
    • The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
    • CARRENO, B.M. & M. COLLINS. 2002. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu. Rev. Immunol. 20: 29-53.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 29-53
    • Carreno, B.M.1    Collins, M.2
  • 10
    • 0035871758 scopus 로고    scopus 로고
    • ICOS costimulation requires IL-2 and can be prevented by CTLA-4 engagement
    • RILEY, J.L. et al. 2001. ICOS costimulation requires IL-2 and can be prevented by CTLA-4 engagement. J. Immunol. 166: 4943-4948.
    • (2001) J. Immunol. , vol.166 , pp. 4943-4948
    • Riley, J.L.1
  • 11
    • 12644262358 scopus 로고    scopus 로고
    • CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
    • KIRK, A.D. et al. 1997. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc. Natl. Acad. Sci. USA 94: 8789-8794.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8789-8794
    • Kirk, A.D.1
  • 12
    • 0029862933 scopus 로고    scopus 로고
    • The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells
    • GRIGGS, N.D. et al. 1996. The relative contribution of the CD28 and gp39 costimulatory pathways in the clonal expansion and pathogenic acquisition of self-reactive T cells. J. Exp. Med. 183: 801-810.
    • (1996) J. Exp. Med. , vol.183 , pp. 801-810
    • Griggs, N.D.1
  • 13
    • 0035555161 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: An autoimmune disease of B cell hyperactivity
    • LIPSKY, P.E. 2001. Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity. Nat. Immunol. 2: 764-766.
    • (2001) Nat. Immunol. , vol.2 , pp. 764-766
    • Lipsky, P.E.1
  • 14
    • 0028483990 scopus 로고
    • Treatment of murine lupus with CTLA4Ig
    • FINCK, B.K., P.S. LINSLEY & D. WOFSY. 1994. Treatment of murine lupus with CTLA4Ig. Science 265: 1225-1227.
    • (1994) Science , vol.265 , pp. 1225-1227
    • Finck, B.K.1    Linsley, P.S.2    Wofsy, D.3
  • 15
    • 0028852328 scopus 로고
    • Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
    • MOHAN, C. et al. 1995. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J. Immunol. 154: 1470-1480.
    • (1995) J. Immunol. , vol.154 , pp. 1470-1480
    • Mohan, C.1
  • 16
    • 0031253956 scopus 로고    scopus 로고
    • Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways
    • DAIKH, D.I. et al. 1997. Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways. J. Immunol. 159: 3104-3108.
    • (1997) J. Immunol. , vol.159 , pp. 3104-3108
    • Daikh, D.I.1
  • 17
    • 0035284737 scopus 로고    scopus 로고
    • Cutting edge: Reversal of murine lupus nephritis with CTLA4Ig and cyclophosphamide
    • DAIKH, D.I. & D. WOFSY. 2001. Cutting edge: reversal of murine lupus nephritis with CTLA4Ig and cyclophosphamide. J. Immunol. 166: 2913-2916.
    • (2001) J. Immunol. , vol.166 , pp. 2913-2916
    • Daikh, D.I.1    Wofsy, D.2
  • 18
    • 0031726050 scopus 로고    scopus 로고
    • B cell receptor-induced apoptosis in primary transitional murine B cells: Signaling requirements and modulation by T cell help
    • SATER, R.A., P.C. SANDEL & J.G. MONROE. 1998. B cell receptor-induced apoptosis in primary transitional murine B cells: signaling requirements and modulation by T cell help. Int. Immunol. 10: 1673-1682.
    • (1998) Int. Immunol. , vol.10 , pp. 1673-1682
    • Sater, R.A.1    Sandel, P.C.2    Monroe, J.G.3
  • 19
    • 0029838992 scopus 로고    scopus 로고
    • Intrinsic B cell defects in NZB and NZW mice contribute to systemic lupus erythematosus in (NZB x NZW)F1 mice
    • REININGER, L. et al. 1996. Intrinsic B cell defects in NZB and NZW mice contribute to systemic lupus erythematosus in (NZB x NZW)F1 mice. J. Exp. Med. 184: 853-861.
    • (1996) J. Exp. Med. , vol.184 , pp. 853-861
    • Reininger, L.1
  • 20
    • 0032541486 scopus 로고    scopus 로고
    • Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells
    • RATHMELL, J.C. et al. 1998. Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells. J. Exp. Med. 188: 651-659.
    • (1998) J. Exp. Med. , vol.188 , pp. 651-659
    • Rathmell, J.C.1
  • 21
    • 0031859661 scopus 로고    scopus 로고
    • Germinal centers: Form and function
    • TARLINTON, D. 1998. Germinal centers: form and function. Curr. Opin. Immunol. 10: 245-251.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 245-251
    • Tarlinton, D.1
  • 22
    • 0032006177 scopus 로고    scopus 로고
    • Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development
    • HANDE, S., E. NOTIDIS & T. MANSER. 1998. Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development. Immunity 8: 189-198.
    • (1998) Immunity , vol.8 , pp. 189-198
    • Hande, S.1    Notidis, E.2    Manser, T.3
  • 23
    • 0031784721 scopus 로고    scopus 로고
    • Epitope spreading: The role of self peptides and autoantigen processing by B lymphocytes
    • MAMULA, M.J. 1998. Epitope spreading: the role of self peptides and autoantigen processing by B lymphocytes. Immunol. Rev. 164: 231-239.
    • (1998) Immunol. Rev. , vol.164 , pp. 231-239
    • Mamula, M.J.1
  • 24
    • 0031895378 scopus 로고    scopus 로고
    • The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment
    • MANSER, T. et al. 1998. The roles of antibody variable region hypermutation and selection in the development of the memory B-cell compartment. Immunol. Rev. 162: 183-196.
    • (1998) Immunol. Rev. , vol.162 , pp. 183-196
    • Manser, T.1
  • 25
    • 0031861905 scopus 로고    scopus 로고
    • Long-lived plasma cells: A mechanism for maintaining persistent antibody production
    • SLIFKA, M.K. & R. AHMED. 1998. Long-lived plasma cells: a mechanism for maintaining persistent antibody production. Curr. Opin. Immunol. 10: 252-258.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 252-258
    • Slifka, M.K.1    Ahmed, R.2
  • 26
    • 0031204780 scopus 로고    scopus 로고
    • Expression of an anti-DNA-associated VII gene in immunized and autoimmune mice
    • ASH-LERNER, A. et al. 1997. Expression of an anti-DNA-associated VII gene in immunized and autoimmune mice. J. Immunol. 159: 1508-1519.
    • (1997) J. Immunol. , vol.159 , pp. 1508-1519
    • Ash-Lerner, A.1
  • 27
    • 0000124809 scopus 로고    scopus 로고
    • Short term costimulatory blockade combined with cyclophosphamide does not abrogate glomerular deposition of antibodies but attenuates the kidney inflammatory response
    • Abstract
    • SINHA J. et al. 2001. Short term costimulatory blockade combined with cyclophosphamide does not abrogate glomerular deposition of antibodies but attenuates the kidney inflammatory response. [Abstract.] Arthritis Rheum. 44: S397.
    • (2001) Arthritis Rheum. , vol.44
    • Sinha, J.1
  • 28
    • 0032769336 scopus 로고    scopus 로고
    • The central and multiple roles of B cells in lupus pathogenesis
    • CHAN, O.T., M.P. MADAIO & M.J. SHLOMCHIK. 1999. The central and multiple roles of B cells in lupus pathogenesis. Immunol. Rev. 169: 107-121.
    • (1999) Immunol. Rev. , vol.169 , pp. 107-121
    • Chan, O.T.1    Madaio, M.P.2    Shlomchik, M.J.3
  • 29
    • 0034949346 scopus 로고    scopus 로고
    • CpG-DNA derived from sera in systemic lupus erythematosus enhances ICAM-1 expression on endothelial cells
    • MIYATA, M. et al. 2001. CpG-DNA derived from sera in systemic lupus erythematosus enhances ICAM-1 expression on endothelial cells. Ann. Rheum. Dis. 60: 685-689.
    • (2001) Ann. Rheum. Dis. , vol.60 , pp. 685-689
    • Miyata, M.1
  • 30
    • 0033590502 scopus 로고    scopus 로고
    • ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
    • HUTLOFF, A. et al. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature 397: 263-266.
    • Nature , vol.397 , pp. 263-266
    • Hutloff, A.1
  • 31
    • 0035804254 scopus 로고    scopus 로고
    • ICOS co-stimulatory receptor is essential for T-cell activation and function
    • DONG, C. et al. 2001. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature 409: 97-101.
    • (2001) Nature , vol.409 , pp. 97-101
    • Dong, C.1
  • 32
    • 0034596948 scopus 로고    scopus 로고
    • Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
    • FREEMAN, G.J. et al. 2000. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192: 1027-1034.
    • (2000) J. Exp. Med. , vol.192 , pp. 1027-1034
    • Freeman, G.J.1
  • 33
    • 0034927194 scopus 로고    scopus 로고
    • PD-1: An inhibitory immunoreceptor involved in peripheral tolerance
    • NISHIMURA, H. & T. HONJO. 2001. PD-1: an inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol. 22: 265-268.
    • (2001) Trends Immunol. , vol.22 , pp. 265-268
    • Nishimura, H.1    Honjo, T.2
  • 34
    • 5944227779 scopus 로고    scopus 로고
    • APRIL and TALL-I and receptors BCMA and TACI: System for regulating humoral immunity
    • YU, G. et al. 2000. APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. Nat. Immunol. 1: 252-256.
    • (2000) Nat. Immunol. , vol.1 , pp. 252-256
    • Yu, G.1
  • 35
    • 0035860466 scopus 로고    scopus 로고
    • BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF
    • THOMPSON, J.S. et al. 2001. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 293: 2108-2111.
    • (2001) Science , vol.293 , pp. 2108-2111
    • Thompson, J.S.1
  • 36
    • 0034694088 scopus 로고    scopus 로고
    • BAFF mediates survival of peripheral immature B lymphocytes
    • BATTEN, M. et al. 2000. BAFF mediates survival of peripheral immature B lymphocytes. J. Exp. Med. 192: 1453-1466.
    • (2000) J. Exp. Med. , vol.192 , pp. 1453-1466
    • Batten, M.1
  • 37
    • 0033532634 scopus 로고    scopus 로고
    • BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
    • SCHNEIDER, P. et al. 1999. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J. Exp. Med. 189: 1747-1756.
    • (1999) J. Exp. Med. , vol.189 , pp. 1747-1756
    • Schneider, P.1
  • 38
    • 0036533385 scopus 로고    scopus 로고
    • BAFFled B cells survive and thrive: Roles of BAFF in B-cell development
    • ROLINK, A.G. & F. Melchers. 2002. BAFFled B cells survive and thrive: roles of BAFF in B-cell development. Curr. Opin. Immunol. 14: 266-275.
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 266-275
    • Rolink, A.G.1    Melchers, F.2
  • 39
    • 0034596831 scopus 로고    scopus 로고
    • Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response
    • DO, R.K. et al. 2000. Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response. J. Exp. Med. 192: 953-964.
    • (2000) J. Exp. Med. , vol.192 , pp. 953-964
    • Do, R.K.1
  • 40
    • 0035167632 scopus 로고    scopus 로고
    • Cutting edge: A role for B lymphocyte stimulator in systemic lupus erythematosus
    • ZHANG, J. et al. 2001. Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. J. Immunol. 166: 6-10.
    • (2001) J. Immunol. , vol.166 , pp. 6-10
    • Zhang, J.1
  • 41
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • MACKAY, F. et al. 1999. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190: 1697-1710.
    • (1999) J. Exp. Med. , vol.190 , pp. 1697-1710
    • Mackay, F.1
  • 42
    • 0037080036 scopus 로고    scopus 로고
    • Ox40 costimulation enhances the development of T cell responses induced by dendritic cells in vivo
    • DE SMEDT, T. et al. 2002. Ox40 costimulation enhances the development of T cell responses induced by dendritic cells in vivo. J. Immunol. 168: 661-670.
    • (2002) J. Immunol. , vol.168 , pp. 661-670
    • De Smedt, T.1
  • 43
    • 0034100170 scopus 로고    scopus 로고
    • CD27/CD70 interactions regulate T dependent B cell differentiation
    • JACQUOT, S. 2000. CD27/CD70 interactions regulate T dependent B cell differentiation. Immunol. Res. 21: 23-30.
    • (2000) Immunol. Res. , vol.21 , pp. 23-30
    • Jacquot, S.1
  • 44
    • 0035660806 scopus 로고    scopus 로고
    • The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT
    • WANG, J. et al. 2001. The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT. J. Clin. Invest. 108: 1771-1780.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1771-1780
    • Wang, J.1
  • 45
    • 0036467421 scopus 로고    scopus 로고
    • Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis
    • SUN, Y. et al. 2002. Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis. J. Immunol. 168: 1457-1465.
    • (2002) J. Immunol. , vol.168 , pp. 1457-1465
    • Sun, Y.1


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