Adenosine induces histamine release from human bronchoalveolar lavage mast cells

Clinical Science

Volumn 96, Issue 4, 1999, Pages 349-355

  Forsythe, P ^a   McGarvey, L P A ^a,b   Heaney, L G ^b   MacMahon, J ^b   Ennis, M ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b BELFAST CITY HOSPITAL   (United Kingdom)

Author keywords

Adenosine; Bronchoalveolar lavage; Histamine release; Mast cells

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 8 [4 (2 AMINOETHYLCARBAMOYL)METHOXYPHENYL] 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; ADENOSINE RECEPTOR STIMULATING AGENT; HISTAMINE;

ADULT; ARTICLE; ASTHMA; BRONCHOSCOPY; BRONCHOSPASM; CONTROLLED STUDY; FEMALE; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTAMINE RELEASE; HUMAN; HUMAN CELL; LUNG LAVAGE; MAJOR CLINICAL STUDY; MALE; MAST CELL; PRIORITY JOURNAL;

EID: 0032901246     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0960349     Document Type: Article

References (30)

1. 1 Marquardt, D. L., Gruber, H. E. and Wasserman, S. I. (1984) Adenosine release from stimulated mast cells. Proc. Natl. Acad. Sci. U.S.A. 81, 6192-6196
2. 2 Fredholm, B. B. (1981) Release of adenosine from rat lung by antigen and compound 48/80. Acta. Physiol. Scand. 111, 507-508
3. 3 Mentzer, Jr., R. M., Rubio, R. and Berne, R. M. (1975) Release of adenosine by hypoxic canine lung tissue and its possible role in pulmonary circulation. Am. J. Physiol. 229, 1625-1631
4. 4 Mann, J. S., Renwick, A. G. and Holgate, S. T. (1986) Release of adenosine and its metabolites from activated human leucocytes. Clin. Sci. 70, 461-468
5. 5 Driver, A. G., Kukoly, C. A., Ali, S. and Mustafa, S. J. (1993) Adenosine in bronchoalveolar lavage fluid in asthma. Am. Rev. Respir. Dis. 148, 91-97
6. 6 Okazaki, T. and Namae, A. (1972) Enhancement of anaphylaxis of isolated smooth muscle by adenosine phosphates and inhibition of anaphylactic mechanisms by adenosine 3′-5′-cyclic monophosphate. Experientia 28, 426-427
7. 7 Peachell, P. T., Columbo, M., Kagey-Sobotka, A., Lichtenstein, M. and Marone, G. (1988) Adenosine potentiates mediator release from human lung mast cells. Am. Rev. Respir. Dis. 138, 1143-1151
8. 2-receptor mediated mechanism. Br. J. Pharmacol. 80, 719-726
9. 9 Cushley, M. J., Tattersfield, A. E. and Holgate, S. T. (1983) Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. Br. J. Clin. Pharmacol. 15, 161-165
10. 10 Mann, J. S., Holgate, S. T., Renwick, A. G. and Cushley, M. J. (1986) Airway effects of purine nucleosides and nucleotides and release with bronchial provocation in asthma. J. Appl. Physiol. 61, 1667-1676
11. 11 Richards, R., Philips, G. D. and Holgate, S. T. (1989) Nedocromil sodium is more potent than sodium cromoglycate against AMP-induced bronchoconstriction in atopic asthmatic subjects. Clin. Exp. Allergy 19, 285-291
12. 12 Philips, G. D., Scott, V. L., Richards, R. and Holgate, S. T. (1989) Comparative protective effects of nedocromil sodium and sodium cromoglycate against bronchoconstriction induced by inhaled adenosine 5′-monophosphate in non-atopic asthma. Eur. Respir. J. 2, 210-217
13. 13 Rafferty, P., Beasley, R., Southgate, P. and Holgate, S. (1987) The role of histamine in allergen and adenosine-induced bronchoconstriction. Int. Arch. Allergy Appl. Immunol. 82, 292-294
14. 14 Polosa, R., Ng, W. H., Crimi, N. et al. (1995) Release of mast-cell-derived mediators after endobronchial adenosine challenge in asthma. Am. J. Respir. Crit. Care Med. 151, 624-629
15. 15 Bergstrand, H. (1980) Phosphodiesterase inhibition and theophylline. Eur. J. Respir. Dis. Suppl. 109, 37-44
16. 16 Pueringer, R. J. and Hunninghake, G. W. (1992) Inflammation and airway reactivity in asthma. Am. J. Med. 92, 32S-38S
17. 17 Ennis, M. (1991) Automated fluorometric assay. In Handbook of Histamine and Histamine Antagonists. Experimental Pharmacology, vol. 97 (Uvnäs, B., ed.), pp. 31-38, Springer-Verlag, Berlin
18. 18 Heaney, L. G., Cross, L. J., Stanford, C. F. and Ennis, M. (1995) Substance P induces histamine release from human pulmonary mast cells. Clin. Exp. Allergy 25, 179-186
19. 19 Marquardt, D. L., Parker, C. W. and Sullivan, T. J. (1978) Potentiation of mast cell mediator release by adenosine. J. Immunol. 120, 871-878
20. 2-purinoreceptor mediated mechanism. Biochem. Pharmacol. 23, 3847-3852
21. 21 Burt, D. S. and Stanworth, D. R. (1983) The effect of ribose and purine modified adenosine analogues on the secretion or histamine from rat mast cells induced by ionophore A23187. Biochem. Pharmacol. 32, 2729-2732
22. 22 Heaney, L. G., Cross, L. J. and Ennis, M. (1998) Histamine release from bronchoalveolar lavage cells from asthmatic subjects after allergen challenge and relationship to the late asthmatic response. Clin. Exp. Allergy 28, 196-204
23. 23 Reeves, J. J., Jones, C. A., Sheehan, M. J., Vardey, C. J. and Whelan, C. J. (1997) Adenosine A3 receptors promote degranulation of rat mast cells both in vitro and in vivo. Inflamm. Res. 46, 180-184
24. 3 receptor agonist 2-Cl-IB-MECA in conscious rats. Eur. J. Pharmacol. 308, 311-314
25. 3 adenosine receptor. Proc. Natl. Acad. Sci. U.S.A. 90, 10365-10369
26. 26 Daxun, Z., Rafferty, P., Richards, R., Summerell, S. and Holgate, S. T. (1989) Airway refractoriness to adenosine 5′-monophosphate after repeated inhalation. J. Allergy Clin. Immunol. 83, 152-158
27. 27 Phillips, G. D., Bagga, P. K., Djukanovic, R. and Holgate, S. T. (1989) The influence of refractoriness to adenosine 5′-monophosphate on allergen-provoked bronchoconstriction in asthma. Am. Rev. Respir. Dis. 140, 321-326
28. 28 Marquardt, D. L. and Walker, L. L. (1987) Inhibition of mast cell adenosine responsiveness by chronic exposure to adenosine receptor agonists. Biochem. Pharmacol. 36, 4297-4302
29. 29 Nyce, J. W. and Metzger, W. J. (1997) DNA antisense therapy for asthma in an animal model. Nature (London) 385, 721-725
30. 2B receptors: a novel therapeutic target in asthma? Trends Pharmacol. Sci. 19, 148-153