Synthesis and antibacterial activity of a novel series of acylides: 3-O-(3-pyridyl)acetylerythromycin A derivatives

Journal of Medicinal Chemistry

Volumn 46, Issue 13, 2003, Pages 2706-2715

  Tanikawa, Tetsuya ^a,b   Asaka, Toshifumi ^a   Kashimura, Masato ^a   Suzuki, Keiko ^a   Sugiyama, Hiroyuki ^a   Sato, Masakazu ^a   Kameo, Kazuya ^a   Morimoto, Shigeo ^a   Nishida, Atsushi ^b  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

11,12 CARBAMATE ACYLIDE; 11,12 DICARBONATE ACYLIDE; 3 O (3 PYRIDYL)ACETYLERYTHROMYCIN A DERIVATIVE; AZITHROMYCIN; ERYTHROMYCIN DERIVATIVE; FMA 0122; LINCOSAMIDE; MACROLIDE; MIKAMYCIN B; TEA 0929; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; HAEMOPHILUS INFLUENZAE; MOUSE; NONHUMAN; PNEUMONIA; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ERYTHROMYCIN; HAEMOPHILUS INFLUENZAE; MACROLIDES; MICE; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; STEREOISOMERISM; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0038115310     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020568d     Document Type: Article

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