메뉴 건너뛰기




Volumn 54, Issue 2, 2000, Pages 433-438

Lack of association of the α2-macroglobulin locus on chromosome 12 in AD

Author keywords

AD; Apolipoprotein E; Chromosome 12; Polymorphism; 2 Macroglobulin

Indexed keywords

ALPHA 2 MACROGLOBULIN; APOLIPOPROTEIN E4; APOLIPOPROTEIN E; MESSENGER RNA;

EID: 0034711618     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.54.2.433     Document Type: Article
Times cited : (48)

References (23)
  • 1
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
    • Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993;261:921-923.
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 2
    • 0027327267 scopus 로고
    • Association of apolipoprotein e allele ∈4 with late-onset familial and sporadic Alzheimer's disease
    • Saunders AM, Strittmatter WJ, Schmechel D, et al. Association of apolipoprotein E allele ∈4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993;43:1467-1472.
    • (1993) Neurology , vol.43 , pp. 1467-1472
    • Saunders, A.M.1    Strittmatter, W.J.2    Schmechel, D.3
  • 3
    • 0028173205 scopus 로고
    • Amyloid-associated proteins α-1 antichymotrypsin and apolipoprotein e promote assembly of Alzheimer β-protein into filaments
    • Ma J, Yee A, Brewer B Jr, Das S, Potter H. Amyloid-associated proteins α-1 antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments. Nature 1994;372:92-94.
    • (1994) Nature , vol.372 , pp. 92-94
    • Ma, J.1    Yee, A.2    Brewer B., Jr.3    Das, S.4    Potter, H.5
  • 4
    • 0027365822 scopus 로고
    • Increased amyloid β-peptide deposition as a consequence of apolipoprotein e genotype in late onset Alzheimer's disease
    • Schmechel DE, Saunders AM, Strittmatter WJ, et al. Increased amyloid β-peptide deposition as a consequence of apolipoprotein E genotype in late onset Alzheimer's disease. Proc Natl Acad Sci USA 1994;90:9649-9653.
    • (1994) Proc Natl Acad Sci USA , vol.90 , pp. 9649-9653
    • Schmechel, D.E.1    Saunders, A.M.2    Strittmatter, W.J.3
  • 5
    • 0028035306 scopus 로고
    • Isoform specific interactions of apolipoprotein e with microtubule-associated protein tau: Implications for Alzheimer's disease
    • Strittmatter WJ, Saunders AM, Goedert M, et al. Isoform specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer's disease. Proc Natl Acad Sci USA 1994;91:11183-11186.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11183-11186
    • Strittmatter, W.J.1    Saunders, A.M.2    Goedert, M.3
  • 6
    • 0028894661 scopus 로고
    • Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein e receptor, the α2-macroglobulin receptor/low-density-lipoprotein receptor-related protein
    • Rebeck GW, Harr SD, Strickland DK, Hyman BT. Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein E receptor, the α2-macroglobulin receptor/low-density-lipoprotein receptor-related protein. Ann Neurol 1995; 37:211-217.
    • (1995) Ann Neurol , vol.37 , pp. 211-217
    • Rebeck, G.W.1    Harr, S.D.2    Strickland, D.K.3    Hyman, B.T.4
  • 7
    • 0029128232 scopus 로고
    • LDL receptor-related protein, a multifunctional Apo e receptor, binds secreted β-amyloid precursor protein and mediates its degradation
    • Kounnas MZ, Moir RD, Rebeck GW, et al. LDL receptor-related protein, a multifunctional Apo E receptor, binds secreted β-amyloid precursor protein and mediates its degradation. Cell 1995;82:331-340.
    • (1995) Cell , vol.82 , pp. 331-340
    • Kounnas, M.Z.1    Moir, R.D.2    Rebeck, G.W.3
  • 8
    • 0026036004 scopus 로고
    • Sequence polymorphism in the human alpha-2-macroglobulin (A2M) gene
    • Poller W, Faber J-P, Olek K. Sequence polymorphism in the human alpha-2-macroglobulin (A2M) gene. Nucleic Acids Res 1992;19:198.
    • (1992) Nucleic Acids Res , vol.19 , pp. 198
    • Poller, W.1    Faber, J.-P.2    Olek, K.3
  • 9
    • 0025899129 scopus 로고
    • A deletion polymorphism in the human alpha-2-macroglobulin (A2M) gene
    • Matthijs G, Marynen P. A deletion polymorphism in the human alpha-2-macroglobulin (A2M) gene. Nucleic Acids Res 1991;19:5102.
    • (1991) Nucleic Acids Res , vol.19 , pp. 5102
    • Matthijs, G.1    Marynen, P.2
  • 10
    • 0030770726 scopus 로고    scopus 로고
    • Complete genomic screen in late onset familial Alzheimer's disease: Evidence for a new locus on chromosome 12
    • Pericak-Vance MA, Bass MP, Yamaoka LH, et al. Complete genomic screen in late onset familial Alzheimer's disease: evidence for a new locus on chromosome 12. JAMA 1998;15-1237-1241.
    • (1998) JAMA
    • Pericak-Vance, M.A.1    Bass, M.P.2    Yamaoka, L.H.3
  • 11
    • 17344362232 scopus 로고    scopus 로고
    • Alpha-2 macroglobulin is genetically associated with Alzheimer's disease
    • Blacker D, Wilcox MA, Laird NM, et al. Alpha-2 macroglobulin is genetically associated with Alzheimer's disease. Nat Genet 1998;19:357-360.
    • (1998) Nat Genet , vol.19 , pp. 357-360
    • Blacker, D.1    Wilcox, M.A.2    Laird, N.M.3
  • 12
    • 7844252287 scopus 로고    scopus 로고
    • Genetic association of an alpha2-macroglobulin (Val1000Ile) polymorphism and Alzheimer's disease
    • Liao A, Nitsch RM, Greenberg SM, et al. Genetic association of an alpha2-macroglobulin (Val1000Ile) polymorphism and Alzheimer's disease. Hum Mol Genet 1998;7:1953-1956.
    • (1998) Hum Mol Genet , vol.7 , pp. 1953-1956
    • Liao, A.1    Nitsch, R.M.2    Greenberg, S.M.3
  • 13
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein e by gene amplification and cleavage with HhaI
    • Hixon JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 1990;31:545-548.
    • (1990) J Lipid Res , vol.31 , pp. 545-548
    • Hixon, J.E.1    Vernier, D.T.2
  • 14
    • 0025801744 scopus 로고
    • Apolipoprotein e geno-typing by one-stage PCR
    • Wenham PR, Price WH, Blundell G. Apolipoprotein E geno-typing by one-stage PCR. Lancet 1991;337:1158-1159.
    • (1991) Lancet , vol.337 , pp. 1158-1159
    • Wenham, P.R.1    Price, W.H.2    Blundell, G.3
  • 15
    • 0029657959 scopus 로고    scopus 로고
    • Molecular biology of APO e alleles in Alzheimer's and non-Alzheimer's dementias
    • Morris CM, Massey HM, Benjamin R, et al. Molecular biology of APO E alleles in Alzheimer's and non-Alzheimer's dementias. J Neural Transm Suppl 1996;47:205-218.
    • (1996) J Neural Transm Suppl , vol.47 , pp. 205-218
    • Morris, C.M.1    Massey, H.M.2    Benjamin, R.3
  • 16
    • 0032470875 scopus 로고    scopus 로고
    • A discordant-sibship test for disequilibrium and linkage: No need for parental data
    • Horvath S, Laird NM. A discordant-sibship test for disequilibrium and linkage: no need for parental data. Am J Hum Genet 1998;63:1886-1897.
    • (1998) Am J Hum Genet , vol.63 , pp. 1886-1897
    • Horvath, S.1    Laird, N.M.2
  • 17
    • 0032959789 scopus 로고    scopus 로고
    • An α-2-macroglobulin insertion-deletion polymorphism in Alzheimer's disease
    • Rogaeva EA, Premkumar S, Grubber J, et al. An α-2-macroglobulin insertion-deletion polymorphism in Alzheimer's disease. Nat Genet 1999;22:19-21.
    • (1999) Nat Genet , vol.22 , pp. 19-21
    • Rogaeva, E.A.1    Premkumar, S.2    Grubber, J.3
  • 18
    • 0032931685 scopus 로고    scopus 로고
    • α-2 Macroglobulin polymorphism and Alzheimer disease risk in the UK
    • Dow DJ, Lindsey N, Cairns NJ, et al. α-2 Macroglobulin polymorphism and Alzheimer disease risk in the UK. Nat Genet 1999;22:16-17.
    • (1999) Nat Genet , vol.22 , pp. 16-17
    • Dow, D.J.1    Lindsey, N.2    Cairns, N.J.3
  • 20
    • 19244362467 scopus 로고    scopus 로고
    • Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein e epsilon 4
    • Rao VS, Cupples A, van Duijn CM, et al. Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4. Am J Hum Genet 1996;59:664-675.
    • (1996) Am J Hum Genet , vol.59 , pp. 664-675
    • Rao, V.S.1    Cupples, A.2    Van Duijn, C.M.3
  • 21
    • 0023756802 scopus 로고
    • The polymorphic human α2-macroglobulin gene (A2M) is located in chromosome region 12p12.3-p13.3
    • Fukushima Y, Bell GI, Shows TB. The polymorphic human α2-macroglobulin gene (A2M) is located in chromosome region 12p12.3-p13.3. Cytogenet Cell Genet 1988;48:58-59.
    • (1988) Cytogenet Cell Genet , vol.48 , pp. 58-59
    • Fukushima, Y.1    Bell, G.I.2    Shows, T.B.3
  • 22
    • 0030752288 scopus 로고    scopus 로고
    • Genetic association of the low density lipoprotein receptor-related protein gene (LRP), an apolipoprotein e receptor, with late onset Alzheimer's disease
    • Kang DE, Saitoh T, Chen X, et al. Genetic association of the low density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late onset Alzheimer's disease. Neurology 1997;49:56-61.
    • (1997) Neurology , vol.49 , pp. 56-61
    • Kang, D.E.1    Saitoh, T.2    Chen, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.