Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase gene

Experimental Neurology

Volumn 167, Issue 2, 2001, Pages 456-459

  Crawford, Fiona C ^a   Freeman, Melissa J ^a   Schinka, John A ^a   Morris, Mark D ^a   Abdullah, Laila I ^a   Richards, Dan ^a   Sevush, Steven ^b   Duara, Ranjan ^c   Mullan, Michael J ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c Mount Sinai Memory Disorder Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; CAUCASIAN; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ETHNIC DIFFERENCE; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL;

EID: 0035130460     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2000.7560     Document Type: Article

References (16)

1. Substantially reduced risk of cancer of the aerodigestive tract in subjects with variant - 463A of the myeloperoxidase gene
2. Gender-specific association of the angiotensin converting enzyme gene with Alzheimer's disease
3. Association between angiotensin-converting enzyme and Alzheimer disease
4. Apolipoprotein E is highly susceptible to oxidation by myeloperoxidase, an enzyme present in the brain
5. Differential oxidation of apolipoprotein E isoforms and interaction with phospholipids
6. Association of a myeloperoxidase promoter polymorphism with multiple sclerosis
7. Association of the myeloperoxidase-463G⇒A polymorphism with lung cancer risk
8. Myeloperoxidase genetic polymorphism and lung cancer risk
9. A thrombin cleavage fragment of apolipoprotein E exhibits isoform-specific neurotoxicity
10. Familial and population-based studies of apolipoprotein E and Alzheimer's disease
11. Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosis
12. An allelic association implicates myeloperoxidase in the etiology of acute promyelocytic leukemia
13. Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease
14. Binding of human apolipoprotein E to synthetic amyloid beta peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
15. Apolipoprotein E genotyping by one-stage PCR
16. Is Alzheimer's disease an apolipoprotein E amyloidosis?